Sinalização Citoesquelética
Os inibidores de sinalização do citoesqueleto são compostos que interrompem as vias de sinalização que regulam o citoesqueleto, crucial para a forma celular, motilidade, divisão e transporte intracelular. Esses inibidores são usados para estudar a dinâmica das proteínas do citoesqueleto, como actina e tubulina, e seu papel em processos como migração celular, adesão e metástase do câncer. Os inibidores de sinalização do citoesqueleto são valiosos na pesquisa em biologia celular, câncer e neurobiologia. Na CymitQuimica, oferecemos uma ampla gama de inibidores de sinalização do citoesqueleto de alta qualidade para apoiar sua pesquisa nessas áreas.
Produtos da "Sinalização Citoesquelética"
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Lenaldekar
CAS:Lenaldekar (LDK) inhibits T-cell expansion and autoimmune encephalomyelitis.Fórmula:C18H14N4Pureza:99.25%Cor e Forma:SolidPeso molecular:286.33Ref: TM-T24398
1mg87,00€2mg124,00€5mg187,00€10mg284,00€25mg452,00€50mg645,00€100mg867,00€200mg1.159,00€1mL*10mM (DMSO)178,00€H2-Gamendazole
CAS:H2-Gamendazole: inhibits spermatogenesis, cancer therapy, targets heat shock proteins & EF1α, regulates Hsp90.Fórmula:C18H13Cl2F3N2O2Pureza:97.36%Cor e Forma:SolidPeso molecular:417.21Ref: TM-T72076
1mg78,00€5mg190,00€10mg284,00€25mg505,00€50mg677,00€100mg929,00€200mg1.225,00€1mL*10mM (DMSO)215,00€TAS-301
CAS:TAS-301, an inhibitor of smooth muscle cell migration and proliferation, inhibits intimal thickening after balloon injury to rat carotid arteries.Fórmula:C23H19NO3Pureza:99.69%Cor e Forma:SolidPeso molecular:357.4Tubulin/AKT1-IN-1
Tubulin/AKT1-IN-1 (Compound D1-1) serves as an inhibitor of both tubulin polymerization and AKT pathway activation, effectively suppressing proliferation andFórmula:C38H34ClNO11Pureza:98%Cor e Forma:SolidPeso molecular:716.13Sovilnesib
CAS:Sovilnesib is a kinesin-like protein KIF18A inhibitor. Sovilnesib can be used for the cancer research.Fórmula:C26H34F2N6O4SPureza:98.59%Cor e Forma:SolidPeso molecular:564.65Ref: TM-T39994
1mg96,00€5mg235,00€10mg376,00€25mg630,00€50mg898,00€100mg1.216,00€1mL*10mM (DMSO)259,00€Fasudil hydrochloride
CAS:Fasudil hydrochloride (HA-1077) is a potent inhibitor of ROCK1, PKA, PKC, and MLCK with Ki of 0.33 μM, 1.0 μM, 9.3 μM and 55 μM, respectively.Fórmula:C14H18ClN3O2SPureza:100% - ≥95%Cor e Forma:White SolidPeso molecular:327.83AKT-IN-3
CAS:AKT-IN-3: potent oral Akt inhibitor with low hERG blockage. IC50: 1.4-1.7 nM for Akt1-3. Inhibits AGC kinases like PKA, PKC.Fórmula:C23H23Cl2F2N5O3Pureza:98%Cor e Forma:SolidPeso molecular:526.36Empesertib
CAS:Empesertib (BAY 1161909) is an orally bioavailable and selective inhibitor Mps1(IC50 < 1 nM), with potential antineoplastic activity.Fórmula:C29H26FN5O4SPureza:97.45% - 98.44%Cor e Forma:SolidPeso molecular:559.61Ref: TM-T8487
1mg90,00€5mg183,00€10mg275,00€25mg449,00€50mg615,00€100mg848,00€200mg1.121,00€1mL*10mM (DMSO)245,00€CC-99677
CAS:CC-99677 (Gamcemetinib) is a MK2 inhibitor targeting autoimmune diseases; potent in rat assays with IC50=156.3 nM & EC50=89 nM.Fórmula:C22H20ClN5O3SPureza:99.51%Cor e Forma:SolidPeso molecular:469.94Ulacamten
CAS:Ulacamten is an effective inhibitor of cardiac myosin (cardiacmyosin).Fórmula:C21H25F2N3O3Cor e Forma:SolidPeso molecular:405.44Enzastaurin
CAS:Enzastaurin (LY317615) (LY317615) is an effective PKCβ selective inhibitor (IC50: 6 nM), 6- to 20-fold selectivity against PKCα/γ/ε.Fórmula:C32H29N5O2Pureza:100% - 99.24%Cor e Forma:SolidPeso molecular:515.6BT100
BT100, an aptamer, impedes the interaction of von Willebrand factor (VWF) with platelet glycoprotein GPIb, thus obstructing arterial thrombosis [1].Pureza:98%Cor e Forma:Odour SolidCilengitide
CAS:Cilengitide (EMD 121974) is a potent integrin inhibitor for the αvβ3/5 receptor (IC50: 4.1/79 nM, in cell-free assays); ~10-fold selectivity against gpIIbIIIa.Fórmula:C27H40N8O7Pureza:98% - 99.8%Cor e Forma:SolidPeso molecular:588.66Ref: TM-T2494
1mg49,00€2mg70,00€5mg96,00€10mg160,00€25mg274,00€50mg439,00€100mg632,00€1mL*10mM (DMSO)137,00€NMS-E973
CAS:NMS-E973 is a potent and selective Hsp90 inhibitor with DC50 of <10 nM for Hsp90 binding, no activiy against a panel of 52 diverse protein kinases.Fórmula:C22H22N4O7Pureza:99.82%Cor e Forma:SolidPeso molecular:454.43Ref: TM-T6609
2mg42,00€5mg64,00€10mg97,00€25mg197,00€50mg310,00€100mg442,00€200mg622,00€1mL*10mM (DMSO)70,00€Hypericin
CAS:Hypericin (Cyclosan) is a natural anthraquinone compound. Hypericin exhibits antimicrobial, antiviral, antitumor, and antidepressant effects. Cost-effective and quality-assured.Fórmula:C30H16O8Pureza:99.05% - ≥98%Cor e Forma:Red-Coloured Anthraquinone-DerivativePeso molecular:504.44Ref: TM-T6S0923
1mg57,00€5mg127,00€10mg182,00€25mg360,00€50mg532,00€100mg743,00€500mg1.510,00€1mL*10mM (DMSO)140,00€Ispinesib
CAS:Ispinesib (SB-715992), a selective, effectvie and reversible inhibitor of kinesin spindle protein (KSP), is derived from quinazolinone, with antineoplasticFórmula:C30H33ClN4O2Pureza:98% - 98.59%Cor e Forma:SolidPeso molecular:517.06Ref: TM-T2103
1mg39,00€2mg50,00€5mg79,00€10mg118,00€25mg210,00€50mg339,00€100mg557,00€500mg1.216,00€1mL*10mM (DMSO)89,00€NCT-58
CAS:NCT-58 is a potent HSP90 inhibitor that blocks Akt, downregulates HER family, and induces apoptosis in HER2+ breast cancer without triggering HSR.Fórmula:C27H34N2O5Pureza:98.75%Cor e Forma:SolidPeso molecular:466.57Ref: TM-T9996
2mg46,00€5mg85,00€10mg126,00€25mg259,00€50mg415,00€100mg662,00€200mg889,00€1mL*10mM (DMSO)207,00€Trimethyloctadecylammonium bromide
CAS:Trimethyloctadecylammonium bromide is an inhibitor of Dynamin I(IC50 : 1.9 μM) and also inhibits Dynamin Ⅱ.Fórmula:C21H46N·BrPureza:99.09%Cor e Forma:Solid SolidPeso molecular:392.5cis-trismethoxy Resveratrol
CAS:cis-trismethoxy Resveratrol ((Z)-3,5,4'-Trimethoxystilbene) inhibits tubulin polymerization (IC50 = 4 μM) and has anti-mitotic effects.Fórmula:C17H18O3Pureza:97.55%Cor e Forma:SolidPeso molecular:270.32Vinflunine Tartrate
CAS:Vinflunine Tartrate, a uniquely fluorinated vinca alkaloid, exhibits mitotic-arresting and tubulin-interacting properties.Fórmula:C45H54F2N4O8·xC4H6O6Pureza:98%Cor e Forma:SolidPeso molecular:967.02Ref: TM-T6722
2mgA consultar5mgA consultar10mgA consultar25mgA consultar50mgA consultar1mL*10mM (DMSO)A consultar
