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Ferroptosis

Ferroptosis

Ferroptosis is a form of regulated cell death characterized by the accumulation of lipid peroxides and iron-dependent oxidative stress. Unlike apoptosis, ferroptosis is not driven by caspases but rather by the failure of cellular antioxidant defenses, leading to cell death. Ferroptosis inhibitors and inducers are critical for studying this unique cell death pathway, which is implicated in various diseases, including cancer, neurodegeneration, and ischemia-reperfusion injury. At CymitQuimica, we offer a wide range of high-quality ferroptosis modulators to support your research in cell death mechanisms, oxidative stress, and disease pathology.

Products of "Ferroptosis"

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products per page.Found 170 products on this category.
  • SRS11-92

    CAS:
    SRS11-92 (AA9) is a ferroptosis inhibitor and a derivative of ferrostatin-1
    Formula:C22H28N2O2
    Purity:98.58%
    Color and Shape:Solid
    Molecular weight:352.47

    Ref: TM-T8922

    1mg
    46.00€
    5mg
    80.00€
    10mg
    116.00€
    25mg
    227.00€
    50mg
    359.00€
    100mg
    550.00€
    500mg
    1,159.00€
    1mL*10mM (DMSO)
    105.00€
  • FSEN1

    CAS:
    FSEN1 is a novel and highly effective non-competitive FSP1 inhibitor with an IC50 value of 313 nM.
    Formula:C22H22BrN5OS
    Purity:98.56%
    Color and Shape:Solid
    Molecular weight:484.41

    Ref: TM-T77765

    1mg
    52.00€
    5mg
    97.00€
    10mg
    160.00€
    25mg
    311.00€
    50mg
    502.00€
    100mg
    777.00€
  • Pro-GA

    CAS:
    Pro-GA is a γ-glutamyl cyclotransferase (GGCT) inhibitor with cell permeability, acting as a diester prodrug with anticancer properties. GGCT is a key enzyme in glutathione metabolism and is involved in the ferroptosis pathway. Pro-GA exhibits an IC50 value of 57 μM against the bladder cancer cell line T24, making it useful for cancer research.
    Formula:C12H19NO7
    Color and Shape:Solid
    Molecular weight:289.28

    Ref: TM-T203386

    10mg
    To inquire
    50mg
    To inquire
  • NYY-6a


    NYY-6a is a ferroptosis (Ferroptosis) inhibitor, demonstrating significant suppression of RSL3-induced ferroptosis in 786-O and HT-1080 cells, with EC50 values of 52 nM and 50 nM, respectively. As a radical-trapping antioxidant (RTA), NYY-6a effectively reduces lipid peroxidation, comparable to ferrostatin-1 and liproxstatin-1, making it useful for research into ferroptosis-related pathologies.
    Formula:C23H22N2O3
    Color and Shape:Solid
    Molecular weight:374.43

    Ref: TM-T205503

    10mg
    To inquire
    50mg
    To inquire
  • DL-Buthionine-(S,R)-sulfoximine

    CAS:
    DL-Buthionine-(S,R)-sulfoximine (Butionine sulfoximine) is an inhibitor of γ-glutamylcysteine synthetase for the treatment of solid tumors.
    Formula:C8H18N2O3S
    Purity:98% - 98.32%
    Color and Shape:White Fine Powder
    Molecular weight:222.31

    Ref: TM-T7708

    25mg
    39.00€
    50mg
    50.00€
  • Rosiglitazone maleate

    CAS:
    Rosiglitazone maleate (BRL 49653) is an oral antidiabetic and potential anticancer agent.
    Formula:C22H23N3O7S
    Purity:99.33% - 99.51%
    Color and Shape:Off-White Solid
    Molecular weight:473.5

    Ref: TM-T1622

    50mg
    34.00€
    100mg
    52.00€
    500mg
    144.00€
    1mL*10mM (DMSO)
    34.00€
  • Zileuton

    CAS:
    Zileuton (A 64077) inhibits 5-lipoxygenase, reduces leukotrienes, aids bronchodilation, lessens mucus/edema, and helps manage asthma symptoms.
    Formula:C11H12N2O2S
    Purity:98.72% - 99.43%
    Color and Shape:Crystalline Solid
    Molecular weight:236.29

    Ref: TM-T0477

    10mg
    35.00€
    25mg
    52.00€
    50mg
    66.00€
    100mg
    95.00€
    200mg
    125.00€
    500mg
    198.00€
    1mL*10mM (DMSO)
    55.00€
  • Pravastatin sodium

    CAS:
    Pravastatin sodium (CS-514 (sodium)), an HMG-CoA reductase inhibitor, inhibits sterol synthesis with IC50 of 5.6 μM.
    Formula:C23H35NaO7
    Purity:97.14%
    Color and Shape:White Crystalline Powder
    Molecular weight:446.52

    Ref: TM-T0672

    10mg
    48.00€
    25mg
    60.00€
    50mg
    72.00€
    100mg
    99.00€
    200mg
    128.00€
    500mg
    205.00€
    1mL*10mM (DMSO)
    44.00€
  • Nordihydroguaiaretic acid

    CAS:
    Nordihydroguaiaretic acid (NDGA) is a natural lipoxygenase (5-LOX) inhibitor. Nordihydroguaiaretic acid has antioxidant effect. Cost-effective and quality-assured.
    Formula:C18H22O4
    Purity:97.82% - 99.91%
    Color and Shape:Solid
    Molecular weight:302.36

    Ref: TM-TJS2190

    50mg
    39.00€
    100mg
    49.00€
    500mg
    131.00€
    1mL*10mM (DMSO)
    57.00€
  • Hemin

    CAS:
    Hemin (Hemin chloride) is a chlorinated iron-containing porphyrin, a heme oxygenase (HO)-1 inducer.
    Formula:C34H32ClFeN4O4
    Purity:98.29% - 99.59%
    Color and Shape:Dark Purple Crystalline Powder
    Molecular weight:651.94

    Ref: TM-T5515

    1g
    48.00€
    5g
    55.00€
    500mg
    35.00€
  • Photosensitizer-5


    Photosensitizer-5, a photodynamic agent, exhibits cytotoxicity towards HeLa and HepG2 cells, with IC50 values of 10.4 nM and 6.9 nM, respectively. It induces cell death through lipid peroxidation via an iron-independent ferroptosis pathway. Additionally, Photosensitizer-5 displays antitumor activity in HeLa-tumor-bearing mice.
    Formula:C35H26BF2IN4O2
    Color and Shape:Solid
    Molecular weight:710.32

    Ref: TM-T200131

    10mg
    To inquire
    50mg
    To inquire
  • Ferrostatin-1

    CAS:
    Formula:C15H22N2O2
    Purity:>98.0%(HPLC)
    Color and Shape:White to Amber to Dark purple powder to crystal
    Molecular weight:262.35

    Ref: 3B-F1302

    25mg
    74.00€
    100mg
    195.00€
  • Roxadustat

    CAS:
    Roxadustat (FG-4592) is an orally bioavailable, hypoxia-inducible factor prolyl hydroxylase inhibitor (HIF-PHI), with potential anti-anemic activity.
    Formula:C19H16N2O5
    Purity:99% - 99.82%
    Color and Shape:Solid
    Molecular weight:352.34

    Ref: TM-T2515

    5mg
    35.00€
    10mg
    52.00€
    25mg
    73.00€
    50mg
    96.00€
    100mg
    116.00€
    500mg
    273.00€
    1mL*10mM (DMSO)
    49.00€
  • CIL56

    CAS:
    CIL56 (CA3) is a small molecule that induces cellular ferroptosis through the production of iron-dependent reactive oxygen species (ROS).
    Formula:C23H27N3O5S2
    Purity:99.46% - 99.91%
    Color and Shape:Solid
    Molecular weight:489.61

    Ref: TM-T4309

    1mg
    37.00€
    2mg
    52.00€
    5mg
    79.00€
    10mg
    115.00€
    25mg
    188.00€
    50mg
    299.00€
    100mg
    459.00€
    1mL*10mM (DMSO)
    86.00€
  • Cetzole

    CAS:
    Cetzole (Compound 1) acts as an inducer of ferroptosis (iron-dependent cell death) through the accumulation of ROS, leading to cell death. The compound exhibits varying half-maximal cytotoxic concentrations (CC50) against several cell lines: 2.56 μM in NCI-H522, 10.31 μM in NCI-H522 GFP-SCL7A11 #8, 2.71 μM in NCI-H522 RV-GFP, 3.07 μM in HT-1080, 14.9 μM in NARF2, and 6.28 μM in MDA-MB-231. This highlights Cetzole's potential for research in cancer therapeutics.
    Formula:C11H11NOS
    Color and Shape:Solid
    Molecular weight:205.28

    Ref: TM-T200746

    25mg
    1,539.00€
    50mg
    1,941.00€
    100mg
    2,451.00€
  • Dopamine hydrochloride

    CAS:
    Dopamine hydrochloride (ASL279) is a naturally occurring catecholamine formed by decarboxylation of dihydroxyphenylalanine and a precursor of norepinephrine and
    Formula:C8H12ClNO2
    Purity:99.56% - 99.76%
    Color and Shape:Solid
    Molecular weight:189.639

    Ref: TM-T1644

    50mg
    35.00€
    100mg
    49.00€
    1mL*10mM (DMSO)
    35.00€
  • Arteannuin B

    CAS:
    1. Arteannuin B has potent antimalarial activity.
    Formula:C15H20O3
    Purity:98% - 99.8%
    Color and Shape:Solid
    Molecular weight:248.32

    Ref: TM-T3S1447

    2mg
    43.00€
    5mg
    80.00€
    10mg
    116.00€
    25mg
    225.00€
    50mg
    376.00€
    100mg
    550.00€
  • L-Cystine

    CAS:
    L-Cystine (Cystine Acid) is not considered one of the 20 amino acids, L-Cystine (Cystine Acid) is a sulfur-containing derivative obtained from oxidation of
    Formula:C6H12N2O4S2
    Purity:99.59% - 99.85%
    Color and Shape:White Solid Powder
    Molecular weight:240.3

    Ref: TM-T2O2733

    1g
    52.00€
    500mg
    48.00€
    1mL*10mM (DMSO)
    52.00€
  • Sorafenib

    CAS:
    Sorafenib (Bay 43-9006) is a multikinase inhibitor that inhibits Raf-1, B-Raf, VEGFR2, VEGFR3, VEGFR4, PDGFRβ, FLT3, c-Kit, and others (IC50=6/22/90/15/20/20/57
    Formula:C21H16ClF3N4O3
    Purity:98% - 99.89%
    Color and Shape:Solid
    Molecular weight:464.82

    Ref: TM-T0093L

    1g
    89.00€
    50mg
    40.00€
    100mg
    52.00€
    500mg
    69.00€
    1mL*10mM (DMSO)
    35.00€
  • Sulfasalazine

    CAS:
    Formula:C18H14N4O5S
    Purity:98%
    Color and Shape:Solid
    Molecular weight:398.3925599999999

    Ref: IN-DA003U6O

    1g
    21.00€
    5g
    21.00€
    10g
    26.00€
    25g
    36.00€
    100g
    79.00€
    500g
    190.00€