Ferroptosis
Ferroptosis is a form of regulated cell death characterized by the accumulation of lipid peroxides and iron-dependent oxidative stress. Unlike apoptosis, ferroptosis is not driven by caspases but rather by the failure of cellular antioxidant defenses, leading to cell death. Ferroptosis inhibitors and inducers are critical for studying this unique cell death pathway, which is implicated in various diseases, including cancer, neurodegeneration, and ischemia-reperfusion injury. At CymitQuimica, we offer a wide range of high-quality ferroptosis modulators to support your research in cell death mechanisms, oxidative stress, and disease pathology.
Products of "Ferroptosis"
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ZX782
ZX782 acts as a GPX4 protein degrader and an inducer of ferroptosis (Ferroptosis), targeting GPX4 for destruction via both the ubiquitin-proteasome system and the autophagy-lysosome pathway. Following the degradation of GPX4 induced by ZX782, there is a significant increase in the accumulation of lipid reactive oxygen species (ROS) in HT1080 cells.Formula:C39H48ClN5O8Color and Shape:SolidMolecular weight:750.28Linagliptin
CAS:Linagliptin (BI 1356) is a potent, orally bioavailable dihydropurinedione-based inhibitor of dipeptidyl peptidase 4 (DPP-4), with hypoglycemic activity.Formula:C25H28N8O2Purity:99.15% - 99.95%Color and Shape:SolidMolecular weight:472.54Simvastatin
CAS:Formula:C25H38O5Purity:>97.0%(HPLC)Color and Shape:White to Almost white powder to crystalMolecular weight:418.57Artemisinin
CAS:Artemisinin (Qinghaosu) is a natural sesquiterpene lactone. Artemisinin has anti-malarial, neuroprotective and anti-tumor effects. Cost-effective and quality-assured.Formula:C15H22O5Purity:100% - 99.87%Color and Shape:Crystalline SolidMolecular weight:282.33Vildagliptin
CAS:Vildagliptin (LAF237), an oral DPP-4 inhibitor with hypoglycemic effects, is metabolized and excreted in urine.Formula:C17H25N3O2Purity:100% - 99.03%Color and Shape:White Crystalline PowderMolecular weight:303.4Gallic Acid Monohydrate
CAS:Gallic Acid Monohydrate, a natural polyhydroxyphenol, which inhibits the free radical scavenging effect of COX-2,antioxidant, anti-tumor, and antibacterial.Formula:C7H8O6Purity:98.02%Color and Shape:SolidMolecular weight:188.14Pioglitazone
CAS:Pioglitazone (U 72107) is an insulin sensitizing agent and thiazolidinedione that is indicated for the treatment of type 2 diabetes.Formula:C19H20N2O3SPurity:95% - 99.57%Color and Shape:White PowderMolecular weight:356.44D-glutamine
CAS:D-glutamine, an D type stereoisomer of glutamine, is one of the 20 amino acids which is encoded by the standard genetic code.Formula:C5H10N2O3Purity:99.99%Color and Shape:White Or Off-White PowderMolecular weight:146.14WITHAFERIN A
CAS:WITHAFERIN A is a novel class of NFkappaB inhibitors, which hold promise as novel anti-inflammatory agents for treatment of various inflammatory disorders and/Formula:C28H38O6Purity:97.41% - 99.83%Color and Shape:SolidMolecular weight:470.6Ref: TM-T5687
1mg85.00€5mg265.00€10mg393.00€25mg653.00€50mg929.00€100mg1,254.00€500mg2,517.00€1mL*10mM (DMSO)304.00€Ebselen
CAS:Formula:C13H9NOSePurity:>98.0%(GC)Color and Shape:Light orange to Yellow to Green powder to crystalMolecular weight:274.18DihydroarteMisinic acid
CAS:DihydroarteMisinic acid (Dihydro-Artmisinic Acid) is a natural product from Artemisia annua and the main direct precursor of artemisinin, which is a medicinalFormula:C15H24O2Purity:99.06% - 99.17%Color and Shape:SolidMolecular weight:236.3584-B10
CAS:84-B10 provides protection in cisplatin-induced acute kidney injury, reversing lipid peroxidation accumulation and downregulation of key ferroptosis inhibitors.Formula:C25H22F3NO5Purity:99.76%Color and Shape:SolidMolecular weight:473.44Ref: TM-T75268
1mg52.00€5mg97.00€10mg169.00€25mg321.00€50mg494.00€100mg742.00€200mg1,008.00€1mL*10mM (DMSO)105.00€BODIPY 581/591 C11
CAS:BODIPY 581/591 C11 is a fluorescent radioactive probe used to indicate lipid peroxidation and antioxidant efficacy in model membrane systems and living cells.Formula:C30H35BF2N2O2Purity:98.83% - 98.90%Color and Shape:SolidMolecular weight:504.42L-Glutamic acid monosodium salt
CAS:L-Glutamic acid monosodium salt (MSG) (Monosodium glutamate) is an activator of mGlu1 receptor.Formula:C5H8NO4·NaPurity:99.93%Color and Shape:White Solid CrystallineMolecular weight:169.11Ferrostatin-1
CAS:View and buy Ferrostatin-1 from TargetMol.Ferrostatin-1 is a potent ferroptosis inhibitor (EC50: 60 nM).Cited in 49 publications.Formula:C15H22N2O2Purity:96.1% - 99.68%Color and Shape:SolidMolecular weight:262.35Simvastatin
CAS:Simvastatin (MK 733) is an HMG-CoA reductase inhibitor (Ki=0.2 nM) with oral activity.Formula:C25H38O5Purity:98.54% - 99.13%Color and Shape:SolidMolecular weight:418.57Ref: TM-T0687
10mg43.00€25mg58.00€50mg69.00€100mg106.00€200mg140.00€500mg270.00€1mL*10mM (DMSO)47.00€PRLX-93936 HCL
CAS:PRLX-93936 HCL is an analog of erastin and demonstrated synergistic effects against non-small cell lung cancer (NSCLC) cells with cisplatin.Formula:C21H26Cl2N4O2Purity:100% - 99.78%Color and Shape:SolidMolecular weight:437.37Sorafenib tosylate
CAS:Sorafenib tosylate (Bay 43-9006) is a potent multikinase inhibitor (IC50s: 6/20/22 nM for Raf-1/VEGFR-3/B-Raf).Formula:C21H16ClF3N4O3·C7H8O3SPurity:99.2% - 99.94%Color and Shape:White To Off-White Crystalline PowderMolecular weight:637.03Piperazine Erastin
CAS:Piperazine erastin is an analog of erastin. It causes an iron-dependent form of non-apoptotic cell death termed ferroptosis.Formula:C35H41ClN6O4Purity:97.74%Color and Shape:SolidMolecular weight:645.19Ref: TM-T16540
1mg96.00€5mg168.00€10mg283.00€25mg567.00€50mg929.00€100mg1,225.00€200mg1,681.00€500mg2,498.00€1mL*10mM (DMSO)240.00€
