Ferroptosis
Ferroptosis is a form of regulated cell death characterized by the accumulation of lipid peroxides and iron-dependent oxidative stress. Unlike apoptosis, ferroptosis is not driven by caspases but rather by the failure of cellular antioxidant defenses, leading to cell death. Ferroptosis inhibitors and inducers are critical for studying this unique cell death pathway, which is implicated in various diseases, including cancer, neurodegeneration, and ischemia-reperfusion injury. At CymitQuimica, we offer a wide range of high-quality ferroptosis modulators to support your research in cell death mechanisms, oxidative stress, and disease pathology.
Products of "Ferroptosis"
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Liproxstatin-1
CAS:Liproxstatin-1 is a potent and selective inhibitor of iron death (IC50=22 nM).Formula:C19H21ClN4Purity:97.11% - 99.9%Color and Shape:SolidMolecular weight:340.85Ref: TM-T2376
2mg52.00€5mg88.00€10mg137.00€25mg255.00€50mg411.00€100mg522.00€200mg750.00€1mL*10mM (DMSO)88.00€ML385
CAS:ML385 is an NRF2 inhibitor (IC50=1.9 μM) with novelty and specificity.Formula:C29H25N3O4SPurity:100% - 99.98%Color and Shape:SolidMolecular weight:511.59Ref: TM-T4360
5mg51.00€10mg79.00€25mg153.00€50mg243.00€100mg376.00€200mg562.00€500mg899.00€1mL*10mM (DMSO)59.00€Cerivastatin sodium
CAS:Cerivastatin sodium (BAY W 6228 sodium) is an HMG-CoA reductase inhibitor with lipid-lowering activity that reduces LDL cholesterol levels.Formula:C26H33FNNaO5Purity:98%Color and Shape:SolidMolecular weight:481.53Ref: TM-T10767
1mg52.00€5mg136.00€10mg235.00€25mg565.00€50mg1,045.00€100mg1,890.00€1mL*10mM (DMSO)612.00€Dp44mT
CAS:Dp44mT, a effective iron chelator, has selective antitumor activity.Formula:C14H15N5SPurity:100% - 98.68%Color and Shape:SolidMolecular weight:285.37FINO2
CAS:FINO2, a strong ferroptosis trigger, blocks GPX4, oxidizes Fe2+, stable in different pH, causes lipid peroxidation.Formula:C15H28O3Purity:97.27%Color and Shape:SoildMolecular weight:256.38Imidazole ketone erastin
CAS:View and buy Imidazole ketone erastin from TargetMol.Imidazole ketone erastin (IKE) is an inducer of ferroptosis. It has inhibition of the system Xc- cystine/glutamate transporter.Cited in 22 publications.Formula:C35H35ClN6O5Purity:98.98% - 99.87%Color and Shape:SolidMolecular weight:655.14Ref: TM-T5523
1mg78.00€2mg97.00€5mg169.00€10mg216.00€25mg373.00€50mg567.00€100mg747.00€1mL*10mM (DMSO)182.00€Chrysosplenetin
CAS:Chrysosplenetin is a metabolic inhibitor of artemisinin.Formula:C19H18O8Purity:97.43% - 98.53%Color and Shape:SolidMolecular weight:374.34Ref: TM-TJS1159
1mg60.00€5mg127.00€10mg188.00€25mg348.00€50mg512.00€100mg730.00€500mg1,483.00€1mL*10mM (DMSO)226.00€Ethylenediaminetetraacetic acid trisodium salt
CAS:Ethylenediaminetetraacetic acid trisodium salt (EDTA Trisodium) used to bind metal ions in the chelation therapy.Formula:C10H13N2Na3O8Purity:99.92% - 99.96%Color and Shape:White CrystalsMolecular weight:358.19Ciclopirox olamine
CAS:Ciclopirox olamine is a broad-spectrum antifungal agent with additional antibacterial and anti-inflammatory activities.Formula:C14H24N2O3Purity:100% - 99.16%Color and Shape:White To Yellow Solid Solid Particulate/PowderMolecular weight:268.35Alogliptin Benzoate
CAS:Alogliptin Benzoate, a potent DPP-4 inhibitor with >10,000-fold selectivity over DPP-8/9, may also curb TLR-4-induced inflammation.Formula:C25H27N5O4Purity:100% - 99.94%Color and Shape:White PowderMolecular weight:461.51Ferrostatin-1 diyne
CAS:Ferrostatin-1 diyne (Fer-1 diyne) (compound 2) serves as an inhibitor of ferroptosis, accumulating in cellular lysosomes, mitochondria, and the endoplasmic reticulum. It notably inhibits ferroptosis independently of lysosomal and mitochondrial activity.Formula:C18H22N2O2Color and Shape:SolidMolecular weight:298.38Brusatol
CAS:Brusatol (NSC-172924) is a natural product isolated from the Brucea javanica plant. It inhibits Nrf2.Formula:C26H32O11Purity:99.35% - 99.82%Color and Shape:SolidMolecular weight:520.53Ref: TM-TQ0211
1mg39.00€5mg94.00€10mg160.00€25mg311.00€50mg502.00€100mg715.00€200mg938.00€1mL*10mM (DMSO)107.00€BCP-T.A
CAS:BCP-T.A is an iron death inducer that acts by binding to GPX4.Formula:C23H19Cl2N3OSPurity:99.49%Color and Shape:SolidMolecular weight:456.39L-Glutamine
CAS:L-Glutamine (L-Glutamic acid 5-amide) , a non-essential amino acid, is synthesized from glutamic acid and ammonia.Formula:C5H10N2O3Purity:99.66% - 99.98%Color and Shape:Solid CrystallineMolecular weight:146.14Erastin
CAS:Formula:C30H31ClN4O4Purity:>98.0%(HPLC)(qNMR)Color and Shape:White to Light yellow powder to crystalMolecular weight:547.056-Hydroxy-2,5,7,8-tetramethylchroman-2-carboxylic Acid
CAS:Formula:C14H18O4Purity:>98.0%(GC)(T)Color and Shape:White to Orange to Green powder to crystalineMolecular weight:250.29Sulfasalazine
CAS:Sulfasalazine (Azulfidine) is a synthetic salicylic acid derivative. Sulfasalazine induces ferroptosis and inhibits NF-κB. Cost effective and quality assured.Formula:C18H14N4O5SPurity:98.00% - 99.28%Color and Shape:Minute Brownish-Yellow CrystalsMolecular weight:398.39Sulfasalazine
CAS:Formula:C18H14N4O5SPurity:>95.0%(T)(HPLC)Color and Shape:Light yellow to Amber to Dark green powder to crystalMolecular weight:398.39Ferroptosis inducer-4
Ferroptosisinducer-4 (Compound 5) is a phospholipid-based ferroptosis inducer featuring a terminal double bond at the sn-2 position. It exhibits significant cytotoxicity towards HT-1080 cells with an IC50 value of 18 μM. The toxicity mechanism involves the generation of lipid peroxides and oxidative damage to the cell membrane induced by the terminal double bond. Ferroptosisinducer-4 can be utilized in studies pertaining to the regulation of ferroptosis.Formula:C33H64NO7PColor and Shape:SolidMolecular weight:617.84L-Glutamic acid
CAS:L-Glutamic acid (Glutaminol) acts as an excitatory transmitter, shows a direct activating effect on the release of DA from dopaminergic terminals.Formula:C5H9NO4Purity:99.14% - 99.55%Color and Shape:White Solid CrystallineMolecular weight:147.13
