Ferroptosis
Ferroptosis is a form of regulated cell death characterized by the accumulation of lipid peroxides and iron-dependent oxidative stress. Unlike apoptosis, ferroptosis is not driven by caspases but rather by the failure of cellular antioxidant defenses, leading to cell death. Ferroptosis inhibitors and inducers are critical for studying this unique cell death pathway, which is implicated in various diseases, including cancer, neurodegeneration, and ischemia-reperfusion injury. At CymitQuimica, we offer a wide range of high-quality ferroptosis modulators to support your research in cell death mechanisms, oxidative stress, and disease pathology.
Products of "Ferroptosis"
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Siramesine hydrochloride
CAS:Siramesine hydrochloride (Lu 28-179 hydrochloride) is a selective sigma-2 receptor agonist, which has been shown to trigger cell death of Y cells and to exhibitFormula:C30H32ClFN2OPurity:100% - 99.75%Color and Shape:SolidMolecular weight:491.04Ref: TM-T1885
1mg60.00€2mg88.00€5mg111.00€10mg173.00€25mg354.00€50mg528.00€100mg743.00€1mL*10mM (DMSO)120.00€Lapatinib Ditosylate
CAS:Lapatinib Ditosylate (Tykerb ditosylate) is an effective EGFR and ErbB2 inhibitor (IC50: 10.8/9.2 nM for EGFR/ErbB2).Formula:C29H26ClFN4O4S·2C7H8O3SPurity:99.41%Color and Shape:Yellow SolidMolecular weight:925.46PD146176
CAS:PD146176 (NSC-168807) is an inhibitor of 15-Lipoxygenase (15-LO) , it inhibits rabbit reticulocyte 15-LO with Ki of 197 nM and IC50 of 0.54 μM.Formula:C15H11NSPurity:98.00%Color and Shape:SolidMolecular weight:237.32Lovastatin
CAS:Lovastatin (MK-803) is an HMG-CoA reductase inhibitor. Lovastatin lowers cholesterol and is used as a lipid-lowering agent. Cost-effective and quality-assured.Formula:C24H36O5Purity:99.59% - 99.72%Color and Shape:The Substance Is A White-Yellowish To Yellow Powder Solid PowderMolecular weight:404.54Cisplatin
CAS:Cisplatin (CDDP) is a DNA cross-linking agent.Formula:Cl2H6N2PtPurity:97.13% - 99.63%Color and Shape:Orange-Yellow To Deep Yellow Solid Or PowderMolecular weight:300.04SP600125
CAS:SP600125 (JNK Inhibitor II) is a JNK inhibitor that inhibits JNK1, JNK2, and JNK3 (IC50=40/40/90 nM) with oral potency, reversibility, and ATP-competitiveFormula:C14H8N2OPurity:97.63% - 99.58%Color and Shape:SolidMolecular weight:220.23Coenzyme Q10
CAS:Formula:C59H90O4Purity:>98.0%(HPLC)Color and Shape:Light yellow to Yellow to Orange powder to crystalMolecular weight:863.37Trolox
CAS:Trolox is a vitamin E analogue, used in reducing oxidative stress or damage.Formula:C14H18O4Purity:98.84% - 99.80%Color and Shape:White To Fainly Beige Crystalline PowderMolecular weight:250.29Ferroptosis-IN-12
Ferroptosis-IN-12 (Cpd-A1) is an inhibitor of ferroptosis. It effectively suppresses ferroptosis in mouse renal tubular epithelial cells (mTECs) treated with Erastin and improves renal function in dose-dependent manners in mouse models of acute kidney injury (AKI) induced by ischemia/reperfusion (I/R) or cecal ligation and puncture (CLP). This compound also reduces renal tubular damage and eliminates inflammation. Exhibiting good plasma stability and high distribution in renal tissues during pharmacokinetic studies in mice, Ferroptosis-IN-12 shows promising potential for research in the field of AKI.Color and Shape:Odour SolidHDAC-IN-77
HDAC-IN-77 (HL-5s), an HDAC inhibitor, has the capability to induce ferroptosis and suppress the Nrf2/HO-1 signaling pathway. This compound is utilized in cancer research.Formula:C22H26N4O2SColor and Shape:SolidMolecular weight:410.53Rosiglitazone hydrochloride
CAS:Rosiglitazone hydrochloride (BRL-49653 HCl) is a blood glucose-lowering drugs, stimulating insulin secretion by binding to the PPAR receptors in fat cells.Formula:C18H19N3O3S·HClPurity:99.63% - 99.79%Color and Shape:SolidMolecular weight:393.89NADPH tetracyclohexanamine
CAS:NADPH tetracyclohexanamine (NADPH (tetracyclohexanamine)) is a cofactor and biological reducing agent.Formula:C45H82N11O17P3Purity:98.73% - 99.05%Color and Shape:SolidMolecular weight:1142.12Pifithrin-α hydrobromide
CAS:Pifithrin-α hydrobromide (Pifithrin-α hydrobromide) is a p53 inhibitor, inhibiting p53-dependent transactivation of p53-responsive genes.Formula:C16H18N2OS·HBrPurity:100% - 98.54%Color and Shape:SolidMolecular weight:367.3DL-α-Tocopherol
CAS:DL-alpha-Tocopherol (Ephanyl) is a synthetic vitamin E that protects skin fibroblasts from the cytotoxic effects of UV light and has antioxidant properties.Formula:C29H50O2Purity:99.60%Color and Shape:Light Yellow Liquid ViscousMolecular weight:430.71SRS16-86
CAS:SRS16-86 is a novel third-generation ferrostatin, is an inhibitor of ferroptosis.Formula:C26H32N4O2Purity:99.85%Color and Shape:SolidMolecular weight:432.56Ref: TM-T9073
1mg37.00€2mg52.00€5mg77.00€10mg114.00€25mg215.00€50mg324.00€100mg484.00€1mL*10mM (DMSO)94.00€CuATSP
CAS:CuATSP is a potent free radical trapping antioxidant (RTA) and ferroptosis inhibitor inhibit lipid peroxidation, for (ALS) and Parkinson's disease.Formula:C18H18CuN6S2Purity:97.09%Color and Shape:SolidMolecular weight:446.05UAMC-3203 hydrochloride
CAS:UAMC-3203 hydrochloride is a potent and selective Ferroptosis inhibitor with an IC50 of 12 nM.Formula:C25H38ClN5O2SPurity:99.62%Color and Shape:SolidMolecular weight:508.12Ref: TM-T8662
2mg49.00€5mg79.00€10mg111.00€25mg170.00€50mg202.00€100mg283.00€200mg420.00€1mL*10mM (DMSO)88.00€Deferasirox
CAS:Deferasirox (CGP-72670) is an oral iron chelating agent used to treat chronic iron overload.Formula:C21H15N3O4Purity:98.79% - 99.4%Color and Shape:SolidMolecular weight:373.36Lepadin H
CAS:Lepadin H, a marine alkaloid and ferroptosis inducer, exhibits significant cytotoxicity by promoting p53 expression, escalating ROS production, and enhancingFormula:C26H45NO3Purity:98%Color and Shape:SolidMolecular weight:419.64FIN56
CAS:FIN56 is a specific inducer of ferroptosis.Formula:C25H31N3O5S2Purity:98.39% - 99.78%Color and Shape:SolidMolecular weight:517.66
