Ferroptosis
Ferroptosis is a form of regulated cell death characterized by the accumulation of lipid peroxides and iron-dependent oxidative stress. Unlike apoptosis, ferroptosis is not driven by caspases but rather by the failure of cellular antioxidant defenses, leading to cell death. Ferroptosis inhibitors and inducers are critical for studying this unique cell death pathway, which is implicated in various diseases, including cancer, neurodegeneration, and ischemia-reperfusion injury. At CymitQuimica, we offer a wide range of high-quality ferroptosis modulators to support your research in cell death mechanisms, oxidative stress, and disease pathology.
Products of "Ferroptosis"
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Anticancer agent 147
CAS:Compound 6j (Anticancer agent 147), a sophoridine derivative and ferroptosis inducer, promotes intracellular accumulation of Fe2+, reactive oxygen species (ROSFormula:C32H40BrN3O2Purity:98%Color and Shape:SolidMolecular weight:578.58BAY 87-2243
CAS:BAY 87-2243 is a potent and selective inhibitor of hypoxia-inducible factor-1 (HIF-1).Formula:C26H26F3N7O2Purity:98% - 99.77%Color and Shape:SolidMolecular weight:525.53Lapatinib
CAS:Lapatinib (GW572016) is an inhibitor of ErbB2 and EGFR (IC50=9.2/10.8 nM) with oral activity.Formula:C29H26ClFN4O4SPurity:99.00% - 99.81%Color and Shape:PowderMolecular weight:581.06JKE-1674
CAS:JKE-1674 is an orally active glutathione peroxidase 4 (GPX4) inhibitor and the active metabolite of ML-210.Cost-effective and quality-assured.Formula:C20H20Cl2N4O4Purity:97.12% - 98.72%Color and Shape:SolidMolecular weight:451.3Ref: TM-T37314
1mg52.00€5mg111.00€10mg173.00€25mg298.00€50mg464.00€100mg747.00€200mg1,017.00€1mL*10mM (DMSO)124.00€Artesunate
CAS:Artesunate (WR-256283) is part of the artemisinin group of drugs that treat malaria.Formula:C19H28O8Purity:99.53% - 99.91%Color and Shape:White Crystalline PowderMolecular weight:384.42ML-210
CAS:ML-210 (CID 49766530) is a glutathione peroxidase 4 (GPX4) inhibitor. ML-210 has antitumor activity and induces ferroptosis. Cost-effective and quality-assured.Formula:C22H20Cl2N4O4Purity:96.7% - 99.03%Color and Shape:SolidMolecular weight:475.32Ref: TM-T8375
1mg40.00€2mg52.00€5mg87.00€10mg140.00€25mg246.00€50mg415.00€100mg597.00€200mg847.00€500mg1,254.00€1mL*10mM (DMSO)90.00€2-(10-hydroxydecyl)-6-methoxy-3-methyl-5-(trideuteriomethoxy)cyclohexa-2,5-diene-1,4-dione
CAS:Formula:C19H30O5Purity:98%Color and Shape:SolidMolecular weight:338.4385Ref: IN-DA00396N
1g29.00€5g45.00€15g93.00€1kgTo inquire25g112.00€2kgTo inquire5kgTo inquire100g177.00€Coenzyme Q10
CAS:Coenzyme Q10 (CoQ10) (ubiquinone) is a naturally occurring compound, acting as the electron carrier in the mitochondrial respiratory chain.Formula:C59H90O4Purity:99.62% - 99.88%Color and Shape:DrypowderMolecular weight:863.34Ammonium iron(III) citrate
CAS:Ammonium iron(III) citrate (Ferric ammonium citrate) is a physiological form of non-ferritin-bound iron that causes intracellular iron overload and iron death.Formula:C24H32Fe3N3O28Purity:98%Color and Shape:Ferric Ammonium Citrate Is A Yellowish Brown To Red Solid With A Faint Odor Of AmmoniaMolecular weight:978.05Butylhydroxyanisole
CAS:BHA is an antioxidant with two isomers: 2-tert-butyl-4-hydroxyanisole and 3-tert-butyl-4-hydroxyanisole.Formula:C11H16O2Purity:99.42% - 99.63%Color and Shape:White Solid WaxyMolecular weight:180.25iFSP1
CAS:iFSP1, a potent, selective, and glutathione-independent ferroptosis suppressor protein 1 (FSP1) (AIFM2) inhibitor with an EC50 of 103 nM, sensitizes diverseFormula:C20H13N5Purity:98.74% - 99.74%Color and Shape:SolidMolecular weight:323.35GPX4-IN-13
CAS:GPX4-IN-13 (compound 16), a GPX4 inhibitor, exhibits anticancer properties by diminishing the expression of GPX4, thereby reducing thyroid cell proliferation and inducing ferroptosis. Additionally, this compound effectively inhibits the growth of three distinct thyroid cancer cell lines: N-thy-ori-3-1 (IC 50 =8.39 μM), MDA-T32 (IC 50 =10.28 μM), and MDA-T41 (IC 50 =8.18 μM).Formula:C23H15NO3Color and Shape:SolidMolecular weight:353.37(-)-Apomorphine hydrochloride hydrate
CAS:(-)-Apomorphine hydrochloride hydrate is a broad-spectrum dopamine agonist and ferroptosis inhibitor.Formula:C17H17NO2HClXH2OColor and Shape:SolidMolecular weight:303.8MMRi62
CAS:MMRi62, a MDM2-MDM4 inhibitor, induces ferroptosis and autophagy in PDAC, degrades FTH1 and mutant p53, and inhibits KRAS/TP53 mutant PDAC in mice.Formula:C21H15Cl2N3OPurity:99.7%Color and Shape:SoildMolecular weight:396.27Ref: TM-T60202
1mg35.00€5mg70.00€10mg104.00€25mg202.00€50mg329.00€100mg525.00€500mg1,121.00€1mL*10mM (DMSO)78.00€Curcumin
CAS:Curcumin (Natural Yellow 3) is a phenolic natural product, an inhibitor of histone acetyltransferase p300/CREB (IC50=25 μM) with specificity.Formula:C21H20O6Purity:95% - 98.98%Color and Shape:Orange-Yellow Crystal Powder; Gives Brownish-Red Color With Alkali; Light-Yellow Color With Acids Physical Description Orange-Yellow Needles (Ntp 1992)Molecular weight:368.3799Erastin
CAS:View and buy Erastin from TargetMol.Erastin is a ferroptosis activator acting on mitochondrial VDAC.Formula:C30H31ClN4O4Purity:98% - 99.75%Color and Shape:SolidMolecular weight:547.04Matrine
CAS:Matrine (Vegard), an alkaloid isolated from the Sophora genus, acts as a kappa opioid receptor agonist.Formula:C15H24N2OPurity:100% - 97.16%Color and Shape:SolidMolecular weight:248.36Butylated hydroxytoluene
CAS:Butylated hydroxytoluene (BHT FCC/NF) is an organic chemical composed of 4-methylphenol modified with tert-butyl groups at positions 2 and 6.Formula:C15H24OPurity:99.72%Color and Shape:Colourless Solid PowderMolecular weight:220.35
