Ferroptosis
Ferroptosis is a form of regulated cell death characterized by the accumulation of lipid peroxides and iron-dependent oxidative stress. Unlike apoptosis, ferroptosis is not driven by caspases but rather by the failure of cellular antioxidant defenses, leading to cell death. Ferroptosis inhibitors and inducers are critical for studying this unique cell death pathway, which is implicated in various diseases, including cancer, neurodegeneration, and ischemia-reperfusion injury. At CymitQuimica, we offer a wide range of high-quality ferroptosis modulators to support your research in cell death mechanisms, oxidative stress, and disease pathology.
Products of "Ferroptosis"
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Deferiprone
CAS:Deferiprone (Deferidone) is an Iron Chelator. The mechanism of action of deferiprone is as an Iron Chelating Activity.Formula:C7H9NO2Purity:99.58% - ≥95%Color and Shape:White NeedlesMolecular weight:139.15α-Vitamin E
CAS:α-Vitamin E (Dexrabeprazole Sodium) is a naturally-occurring form of vitamin E, a fat-soluble vitamin with potent antioxidant properties.Formula:C29H50O2Purity:98% - 99.89%Color and Shape:Light Yellow LiquidMolecular weight:430.71GPX4-IN-14
GPX4-IN-14 (compound 2c) acts as a GPX4 inhibitor, exhibiting both free radical scavenging activity (with a maximum scavenging rate of 72.52%) and anti-tumor proliferation activity in vitro. This compound targets GPX4 protein, elevating lipid peroxide and intracellular Reactive Oxygen Species (ROS) levels, which induces ferroptosis and contributes to its anti-tumor proliferation effects.Formula:C26H39NO8SeColor and Shape:SolidMolecular weight:572.55Alogliptin
CAS:Alogliptin (SYR-322)(SYR-322) is a potent, selective inhibitor of DPP-4 with IC50 of <10 nM, exhibits greater than 10, 000-fold selectivity over DPP-8 and DPP-9Formula:C18H21N5O2Purity:99.63%Color and Shape:SolidMolecular weight:339.39Ref: TM-T6192
2mg35.00€5mg50.00€10mg66.00€25mg89.00€50mg97.00€100mg144.00€200mg207.00€1mL*10mM (DMSO)56.00€Ferroptosis inducer-6
CAS:Ferroptosisinducer 6 (6d) is an inducer of ferroptosis (ferroptosis) that exhibits potent potential for Type I/II photodynamic therapy by inducing ROS production, oxidative stress, and mitochondrial damage. Additionally, it demonstrates antitumor activity.Formula:C69H78F12N12P2RuColor and Shape:SolidMolecular weight:1466.44ML162
CAS:ML162 is a covalent glutathione peroxidase 4 (GPX4) inhibitor that induces ferroptosis. ML162 has antitumor activity. Cost-effective and quality-assured.Formula:C23H22Cl2N2O3SPurity:98.42% - 99.78%Color and Shape:SolidMolecular weight:477.4TOFA-Plasmalogen
TOFA-Plasmalogen (compound 1), a derivative of glyceraldehyde, exhibits ferroptosis-inducing properties. This compound promotes lipid peroxidation in cell membranes, leading to cytotoxic effects with an inhibition concentration (IC 50 = 32.87 μM).Formula:C33H62NO7PColor and Shape:SolidMolecular weight:615.82Baicalein
CAS:Baicalein (5,6,7-Trihydroxyflavone) is a xanthine oxidase inhibitor.Formula:C15H10O5Purity:95.79% - 97.25%Color and Shape:Yellow Crystalline SolidMolecular weight:270.24DL-Glutamine
CAS:DL-Glutamine, a non-essential amino acid, is abundant in the body, aids metabolism, carries nitrogen, and fuels cells.Formula:C5H10N2O3Purity:99.89%Color and Shape:White Crystalline Powder White Crystalline PowderMolecular weight:146.14Troglitazone
CAS:Troglitazone (Romglizone) is a PPARγ agonist with anti-inflammatory and anti-tumor activity.Formula:C24H27NO5SPurity:98% - 99.62%Color and Shape:Yellow SolidMolecular weight:441.54Ref: TM-T3170
2mg42.00€5mg62.00€10mg88.00€25mg172.00€50mg305.00€100mg558.00€500mg1,169.00€1mL*10mM (DMSO)85.00€(-)-Epicatechin
CAS:(-)-Epicatechin (Epicatechin) is an inhibitor of cyclooxygenase-1 (COX-1), inhibiting the IL-1β-induced expression of iNOS by blocking the nuclear localizationFormula:C15H14O6Purity:97.34% - 98.55%Color and Shape:SolidMolecular weight:290.27Eprenetapopt
CAS:Eprenetapopt (PRIMA-1Met) restores wild-type conformation and function to mutant p53, and triggers apoptosis in tumor cells.Formula:C10H17NO3Purity:98.75% - 99.57%Color and Shape:SolidMolecular weight:199.25Ref: TM-T4414
5mg73.00€10mg105.00€25mg207.00€50mg368.00€100mg652.00€500mg1,320.00€1mL*10mM (DMSO)81.00€Ferroptosis-IN-1
Ferroptosis-IN-1, a diterpene derived from A.Formula:C22H34O5Purity:98%Color and Shape:SolidMolecular weight:378.5Levobupivacaine
CAS:Levobupivacaine is an amino-amide local anaesthetic drug belonging to the family of n-alkylsubstituted pipecoloxylidide.Formula:C18H28N2OPurity:99.72%Color and Shape:SolidMolecular weight:288.43Ref: TM-T1787
5mg48.00€10mg63.00€25mg93.00€50mg136.00€100mg188.00€200mg283.00€500mg487.00€1mL*10mM (DMSO)49.00€Coenzyme Q9
CAS:Formula:C54H82O4Purity:>98.0%(HPLC)Color and Shape:Light yellow to Yellow to Orange powder to crystalMolecular weight:795.25PRIMA-1
CAS:PRIMA-1 (NSC-281668) is a mutant p53 reactivator. It induces apoptosis and inhibits growth of human tumors with mutant p53.Formula:C9H15NO3Purity:99.22%Color and Shape:SolidMolecular weight:185.22Ref: TM-T6954
5mg51.00€10mg73.00€25mg140.00€50mg207.00€100mg368.00€200mg547.00€500mg877.00€1mL*10mM (DMSO)57.00€Baicalein
CAS:Formula:C15H10O5Purity:>98.0%(T)Color and Shape:Light yellow to Amber to Dark green powder to crystalMolecular weight:270.24CAR-2
CAS:CAR-2 is a BODIPY-based photosensitizer that induces ferroptosis in photodynamic therapy (PDT) by targeting the endoplasmic reticulum (ER) and lipid droplets (LD). It exhibits phototoxicity against breast cancer cells with an IC50 of 0.01-0.02 μM and demonstrates antitumor efficacy in a 4T1 xenograft mouse model.Formula:C27H23BF2I2N4O2Color and Shape:SolidMolecular weight:738.114RSL3
CAS:View and buy RSL3 from TargetMol.RSL3 is a VDAC-independent ferroptosis activator.Cited in 10 publications.Formula:C23H21ClN2O5Purity:98% - 99.96%Color and Shape:SolidMolecular weight:440.88Ref: TM-T3646
1g1,359.00€1mg39.00€2mg51.00€5mg79.00€10mg126.00€25mg258.00€50mg349.00€100mg459.00€500mg1,026.00€1mL*10mM (DMSO)74.00€
