HSP
HSP (Heat Shock Protein) inhibitors target HSPs, a family of molecular chaperones that assist in protein folding, stability, and protection against stress-induced damage. HSPs are often upregulated in cancer cells, helping them survive under stressful conditions such as hypoxia and chemotherapy. Inhibiting HSPs can disrupt these protective mechanisms, leading to cell death. HSP inhibitors are therefore valuable in cancer therapy and research into stress responses. At CymitQuimica, we provide a comprehensive range of high-quality HSP inhibitors to support your research in protein homeostasis, stress responses, and oncology.
Products of "HSP"
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Ganetespib
CAS:Ganetespib (STA-9090) is a synthetic small-molecule inhibitor of heat shock protein 90 (Hsp90) with potential antineoplastic activity.Formula:C20H20N4O3Purity:97.29% - 99.95%Color and Shape:SolidMolecular weight:364.4Ref: TM-T2309
5mg66.00€10mg87.00€25mg133.00€50mg166.00€100mg250.00€200mg424.00€500mg702.00€1mL*10mM (DMSO)74.00€Teprenone
CAS:Teprenone (Geranylgeranylacetone) is a anti-ulcer drug, and works as an inducer of heat shock proteins (HSPs).Formula:C23H38OPurity:99.76% - 99.96%Color and Shape:SolidMolecular weight:330.55SMTIN-T140
CAS:SMTIN-T140: strong TRAP1 inhibitor, IC50=1.646μM, anticancer; disrupts mitochondria, boosts ROS, activates AMPK, shrinks PC3 tumors, no in vivo toxicity.Formula:C36H34BrClFN5OPPurity:98%Color and Shape:SolidMolecular weight:718.02Arimoclomol maleate
CAS:Arimoclomol maleate (BRX-220) (BRX-220) is a heat shock protein (HSP) co-inducer.Formula:C18H24ClN3O7Purity:99.9% - 99.98%Color and Shape:SolidMolecular weight:429.85Alvespimycin hydrochloride
CAS:Alvespimycin hydrochloride (BMS 826476) is a potent HSP90 inhibitor with IC50 of 62 nM. Phase 2.Formula:C32H48N4O8·HClPurity:99.94%Color and Shape:SolidMolecular weight:653.21JG-231
CAS:JG-231, a JG-98 analog, shows anticancer properties by blocking Hsp70-BAG3 interaction and hindering TNBC in MDA-MB-231 models.Formula:C22H18BrCl2N3OS4Purity:99.21%Color and Shape:SolidMolecular weight:619.47DDO-5936
CAS:DDO-5936 is a potent and specific HSP90-Cdc37 PPI inhibitor.Formula:C25H29N5O4SPurity:99.81%Color and Shape:SolidMolecular weight:495.59Ref: TM-T9202
1mg37.00€5mg80.00€10mg126.00€25mg264.00€50mg389.00€100mg553.00€200mg750.00€1mL*10mM (DMSO)88.00€HM03
CAS:HM03 is a potent and selective inhibitor of HSPA5, and has anticancer activity.Formula:C26H27ClN4O2Purity:97.15%Color and Shape:SolidMolecular weight:462.97L-Alanyl-L-glutamine
CAS:L-Alanyl-L-glutamine (Ala-Gln), a dipeptide composed of alanine and Gln, is an alternative supplement to L-glutamine in the production of biopharmaceuticals.Formula:C8H15N3O4Purity:99.71% - 99.97%Color and Shape:SolidMolecular weight:217.22Palmitic acid
CAS:Palmitic acid (Cetylic acid) is a natural product, a common saturated fatty acid found in animals, plants and microorganisms.Formula:C16H32O2Purity:99.17% - 99.67%Color and Shape:White Crystalline Scales SolidMolecular weight:256.42C086
CAS:C086 is a novel and potent Hsp90 inhibitor that suppresses cell cycle progression, induces apoptosis, and exhibits anti-metastatic properties by modulating various mechanisms in different cell types.Formula:C29H28O8Color and Shape:SolidMolecular weight:504.53HSP90-IN-27
CAS:HSP90-IN-27, also known as compound 19, is an inhibitor of HSP90 [1].Formula:C18H21N3O2SPurity:98%Color and Shape:SolidMolecular weight:343.44Alvespimycin
CAS:Alvespimycin (17-DMAG) is a potent Hsp90 inhibitor with potential anticancer activity, which acts by binding to Hsp90.Formula:C32H48N4O8Purity:100%Color and Shape:SolidMolecular weight:616.75NPX800
CAS:NPX800 is an inhibitor of heat shock factor 1 (HSF1) and can be used in studies about the treatment of cancer.Formula:C32H32FN5O4Purity:99.26%Color and Shape:SolidMolecular weight:569.63Ref: TM-T9804
1mg96.00€5mg240.00€10mg375.00€25mg627.00€50mg893.00€100mg1,216.00€1mL*10mM (DMSO)300.00€Radicicol
CAS:Radicicol is an antifungal antibiotic, a inhibitor of Hsp90 & FTO, Anti-malarial , inhibits iNOS gene expression by blocking the p38 kinase and NF-κB/Rel.Formula:C18H17ClO6Purity:98%Color and Shape:White/Yellow PowderMolecular weight:364.78Azadiradione
CAS:Azadiradione (AZD) (AZD) from the methanolic extract of seeds of Azadirachta indicaFormula:C28H34O5Purity:99.52% - 99.52%Color and Shape:SolidMolecular weight:450.57Ref: TM-TN6729
1mg131.00€5mg286.00€10mg515.00€25mg777.00€50mg1,074.00€100mg1,454.00€1mL*10mM (DMSO)354.00€GRP78-IN-3
CAS:GRP78-IN-3: Potent Hsp70 blocker, selective Grp78 (HSPA5) inhib., IC50 0.59 μM, 7x more vs HspA9, 20x vs HspA2.Formula:C17H18N4O2SPurity:99.11%Color and Shape:SoildMolecular weight:342.42IPI-493
CAS:IPI-493 is a bioactive chemical.Formula:C28H39N3O8Purity:100%Color and Shape:SolidMolecular weight:545.62VER-49009
CAS:VER-49009 (CCT 129397) is a potent Hsp90 inhibitor(IC50 of 25 nM and Kd of 78 nM).Formula:C19H18ClN3O4Purity:99.36% - 99.99%Color and Shape:SolidMolecular weight:387.82Ref: TM-T3454
2mg46.00€5mg64.00€10mg92.00€25mg164.00€50mg259.00€100mg354.00€200mg500.00€1mL*10mM (DMSO)52.00€Pimitespib
CAS:Pimitespib (TAS-116) is an ATP-competitive and highly specific HSP90α/HSP90β inhibitor (Kis: 34.7 nM and 21.3 nM, respectively).Formula:C25H26N8OPurity:99.22% - 99.49%Color and Shape:SolidMolecular weight:454.53
