Chromatin/Epigenetics
Chromatin/epigenetics inhibitors are compounds that modulate the structure and function of chromatin or interfere with epigenetic modifications, such as DNA methylation and histone modification. These inhibitors are essential tools for studying gene expression regulation and the role of epigenetics in diseases like cancer, neurological disorders, and developmental abnormalities. By targeting epigenetic processes, these inhibitors can alter gene expression patterns and offer new therapeutic avenues. At CymitQuimica, we provide a wide selection of high-quality chromatin/epigenetics inhibitors to support your research in molecular biology, genetics, and epigenetics.
Subcategories of "Chromatin/Epigenetics"
Products of "Chromatin/Epigenetics"
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Panaxadiol
CAS:Panaxadiol (20(R)-Panaxadiol) is a novel antitumor agent extracted from the Chinese medical herb Panax ginseng.Formula:C30H52O3Purity:98% - 99.9%Color and Shape:SolidMolecular weight:460.73CFT8634
CAS:CFT8634 degrades BRD9, for synovial sarcoma and SMARCB1 tumor research, from patent WO2021178920A1.Formula:C37H45F3N6O5Color and Shape:SolidMolecular weight:710.79OXFBD04
CAS:OXFBD04: Potent BRD4 inhibitor, IC50=166nM, acts on BET bromodomains; moderate CREBBP affinity; anti-cancer properties.Formula:C17H16N2O3Purity:98.84%Color and Shape:SolidMolecular weight:296.32Ref: TM-T12338
1mg64.00€5mg140.00€10mg221.00€25mg411.00€50mg610.00€100mg827.00€200mg1,103.00€1mL*10mM (DMSO)156.00€P300-IN-4
P300-IN-4 (compound 6) is a histone acetyltransferase p300 inhibitor with an IC50 value of 12.2 μM.Formula:C29H28ClIN4O5Color and Shape:SolidMolecular weight:674.91ZM39923 hydrochloride
CAS:ZM39923 hydrochloride (JAK3 Inhibitor IV) is an JAK1/3 inhibitor, almost no activity to JAK2 and modestly potent to EGFR; also is sensitive to transglutaminase.Formula:C23H25NO·HClPurity:98.05%Color and Shape:SolidMolecular weight:367.91MC4171
MC4171 is a selective KAT8 inhibitor with antiproliferative activity and can be used to study cancer.Formula:C21H15N3O3Purity:98.77%Color and Shape:SolidMolecular weight:357.36PROTAC BRD4 Degrader-5
CAS:PROTAC BRD4 Degrader-5 is a PROTAC that degrades BRD4 in HER2 positive and negative breast cancer cell lines.Formula:C50H62ClN9O8S2Color and Shape:SolidMolecular weight:1016.67OUL232
CAS:OUL232 is a potent single ARTs PARP7, PARP10, PARP11, PARP12, PARP14 and PARP15 inhibitor for cancer and tumour research.Formula:C10H10N4O2SPurity:99.04%Color and Shape:SolidMolecular weight:250.28Niraparib hydrochloride
CAS:Niraparib hydrochloride (MK-4827) is a PARP inhibitor with potential cancer treatment effects, causing DNA damage and apoptosis.Formula:C19H21ClN4OPurity:99.26%Color and Shape:SolidMolecular weight:356.85ABBV-712
CAS:ABBV-712 is a selective Tyrosine Kinase 2 (TYK2) inhibitor, demonstrating an IC50 value of 0.195 μM, and is implicated in the regulation of autoimmune diseasesFormula:C24H28N4O5Purity:98%Color and Shape:SolidMolecular weight:452.5Bromosporine
CAS:Bromosporine is a broad spectrum inhibitor for bromodomains for BRD2/4/9 and CECR2 (IC50: 0.41/0.29/0.122/0.017 μM), respectively.Formula:C17H20N6O4SPurity:99.4% - 99.65%Color and Shape:SolidMolecular weight:404.44Ref: TM-T6255
1mg52.00€5mg97.00€10mg180.00€25mg330.00€50mg560.00€100mg810.00€500mg1,605.00€1mL*10mM (DMSO)111.00€AS8351
CAS:AS8351 inhibits histone demethylase, used with various compounds to turn human lung fibroblasts into cardiomyocytes.Formula:C17H13N3O2Purity:99.54% - 99.72%Color and Shape:SolidMolecular weight:291.3Ref: TM-T4100
5mg50.00€10mg70.00€25mg116.00€50mg188.00€100mg350.00€200mg455.00€500mg745.00€1mL*10mM (DMSO)51.00€4-amino-1,8-Naphthalimide
CAS:4-amino-1,8-Naphthalimide (4-ANI) is a PARP inhibitor with IC50 of 180 nMFormula:C12H8N2O2Purity:95.13%Color and Shape:Yellow Solid PowderMolecular weight:212.2WHI-P97
CAS:WHI-P97 is a rationally designed potent inhibitor of JAK-3.Formula:C16H13Br2N3O3Purity:99.93%Color and Shape:SolidMolecular weight:455.1GS-626510
CAS:GS-626510 is an orally bioavailable inhibitor of BET family bromodomains (Kd: 0.59-3.2 nM for BRD2/3/4; IC50: 83 nM and 78 nM for BD1 and BD2).Formula:C25H22N4OColor and Shape:SolidMolecular weight:394.47Pim-1 kinase inhibitor 11
Pim-1 kinase inhibitor 11 (10f) is an inhibitor of PIM-1 with an IC50 value of 0.18 μM. It exhibits anticancer activity by inducing apoptosis and causing cell cycle arrest.Color and Shape:Odour SolidLin281632
CAS:Lin281632 is an inhibitor of RNA binding protein Lin28 and bromodomain. Lin281632 promotes mESC differentiation.Formula:C15H15N5OPurity:99.8%Color and Shape:SolidMolecular weight:281.31Ref: TM-T27835
1mg35.00€5mg74.00€10mg106.00€25mg224.00€50mg359.00€100mg565.00€500mg1,206.00€1mL*10mM (DMSO)84.00€AURKA against 1
Compound Ac13, also termed AURKA against 1, acts as an inhibitor of the Aurora kinase (AURKA) with an IC50 of less than 0.5 nM, targeting the acetylation of endogenous lysine (K162) and exhibiting anti-tumor cell proliferation activity. The kinase activity of AURKA, acetylated at K162 and induced by AURKA against 1, is reversibly restored in HCT116 cells transfected with SIRT3.Formula:C28H32FN9O2Color and Shape:SolidMolecular weight:545.61Tazemetostat trihydrochloride
CAS:Tazemetostat trihydrochloride, an EZH2 inhibitor, orally active, IC50: 4nM (rat), Ki: 2.5nM (human), effective in peptide and nucleosome assays.Formula:C34H47Cl3N4O4Purity:98%Color and Shape:SolidMolecular weight:682.125-Hydroxy-7-acetoxy-8-methoxyflavone
CAS:5-Hydroxy-7-acetoxy-8-methoxyflavone is a flavonoid compound that inhibits lipid peroxidation and may have anti-influenza virus activity.Formula:C18H14O6Purity:≥98%Color and Shape:SolidMolecular weight:326.3
