Chromatin/Epigenetics
Chromatin/epigenetics inhibitors are compounds that modulate the structure and function of chromatin or interfere with epigenetic modifications, such as DNA methylation and histone modification. These inhibitors are essential tools for studying gene expression regulation and the role of epigenetics in diseases like cancer, neurological disorders, and developmental abnormalities. By targeting epigenetic processes, these inhibitors can alter gene expression patterns and offer new therapeutic avenues. At CymitQuimica, we provide a wide selection of high-quality chromatin/epigenetics inhibitors to support your research in molecular biology, genetics, and epigenetics.
Subcategories of "Chromatin/Epigenetics"
Products of "Chromatin/Epigenetics"
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ZLD1039
CAS:ZLD1039, an oral EZH2 inhibitor, shows strong PRC2 inhibition at low nanomolar IC50s, and halts breast cancer growth and spread.Formula:C36H48N6O3Purity:99.82%Color and Shape:SolidMolecular weight:612.8BMS-911543
CAS:BMS-911543 is a potent and selective inhibitor of JAK2 with IC50 of 1.1 nM, ~350-, 75- and 65-fold selective to JAK1, JAK3 and TYK2, respectively. Phase 1/2.Formula:C23H28N8OPurity:97.69% - 99.98%Color and Shape:SolidMolecular weight:432.52Adaptaquin
CAS:Adaptaquin is an inhibitor of the hypoxia-inducing factor prolyl hydroxylase (HIF-PH) [1] [2].Formula:C21H16ClN3O2Purity:98.35%Color and Shape:SolidMolecular weight:377.82PHD2-IN-4
CAS:PHD2-IN-4 (compound 1) is an inhibitor of PHD2, with an IC50 of 4 nM. It is utilized in research related to chronic kidney disease.Formula:C21H19N5O3Color and Shape:SolidMolecular weight:389.407Picolinamide
CAS:Picolinamide (Picolinoylamide) is found to be a strong inhibitor of poly (ADP-ribose) synthetase of nuclei from rat pancreatic islet cells.Formula:C6H6N2OPurity:99.60%Color and Shape:SolidMolecular weight:122.12IV-275
IV-275 is a dual inhibitor targeting the bromodomains of both BRG1 and BRM.Formula:C19H18F2N2O3Purity:98%Color and Shape:SolidMolecular weight:360.35Antidiabetic agent 7
Antidiabetic agent 7 (Compound 5m) functions as a potent hyperglycemia inhibitor. It effectively stimulates GLUT4 translocation in skeletal muscle cells by activating the AMPK-dependent pathway. Additionally, this compound is capable of reducing blood glucose levels and exhibits favorable pharmacokinetic properties. Antidiabetic agent 7 is suitable for research related to antihyperglycemic treatments.Formula:C27H21Cl2N5O3Color and Shape:SolidMolecular weight:534.39Ziftomenib
CAS:Ziftomenib (KO-539) is an inhibitor of menin-MLL interaction with antitumor activity and can be used to study leukemia.Formula:C33H42F3N9O2S2Purity:99.65%Color and Shape:SolidMolecular weight:717.871TM6089
CAS:TM6089 is an inhibitor of Prolyl Hydroxylase that stimulates HIF activity without iron chelation, induces angiogenesis, and protects organ against ischemia.Formula:C13H14N4O3SPurity:99.07%Color and Shape:SolidMolecular weight:306.34Ref: TM-T17105
1mg74.00€5mg164.00€10mg239.00€25mg430.00€50mg645.00€100mg940.00€200mg1,264.00€1mL*10mM (DMSO)170.00€Oltipraz
CAS:Oltipraz (RP 35972) is a synthetic dithiolethione with potential chemopreventive and anti-angiogenic properties.Formula:C8H6N2S3Purity:100% - 99.56%Color and Shape:SolidMolecular weight:226.34BET bromodomain inhibitor
CAS:BET bromodomain inhibitor is a potent BET inhibitor.Formula:C24H20ClN5O2Purity:98.22% - 99.26%Color and Shape:SolidMolecular weight:445.9PARP1/2-IN-4
CAS:PARP1/2-IN-4 (compound 3) is an inhibitor of PARP1/2.Formula:C23H30FN5O6Color and Shape:SolidMolecular weight:491.515-Fluoro-2'-deoxycytidine
CAS:5-Fluoro-2'-deoxycytidine (2'-DEOXY-5-FLUOROCYTIDINE) is an inhibitor of DNA methyltransferase (DNMT) .Formula:C9H12FN3O4Purity:97.91%Color and Shape:Fine White PowderMolecular weight:245.21Ref: TM-T7718
2mg35.00€5mg50.00€10mg67.00€25mg96.00€50mg145.00€100mg210.00€200mg313.00€500mg525.00€1mL*10mM (DMSO)52.00€GDC-0339
CAS:GDC-0339: oral Pim kinase inhibitor for multiple myeloma (Kis: Pim1 - 0.03 nM, Pim2 - 0.1 nM, Pim3 - 0.02 nM), well-tolerated.Formula:C20H22F3N7OSColor and Shape:SolidMolecular weight:465.5Decernotinib
CAS:Decernotinib (VRT-831509)(VX-509; VRT-831509) is a potent and selective Janus kinase 3 (JAK3) inhibitor with Ki of 2.5 nM; IC50 is 50-170 nM in cellular assays.Formula:C18H19F3N6OPurity:100% - 99.45%Color and Shape:SolidMolecular weight:392.38Ref: TM-T2636
1mg38.00€2mg52.00€5mg79.00€10mg110.00€25mg217.00€50mg329.00€100mg494.00€200mg705.00€1mL*10mM (DMSO)88.00€PROTAC SMARCA2 degrader-28
CAS:PROTAC SMARCA2 degrader-28 (Compound 158) is a potent SMARCA2 PROTAC degrader that achieves degradation of SMARCA2 in HiBiT A549 cells, exhibiting a DC50 of 3 nM.Formula:C50H51F7N10O10Color and Shape:SolidMolecular weight:1084.99CTPB
CAS:CTPB is a potent p300 histone acetyltransferase (HAT) activator that can be used in the preparation of hair growth promoters and/or hair loss treatments.Formula:C31H43ClF3NO2Purity:99.77%Color and Shape:SolidMolecular weight:554.13MRTX-1719
CAS:MRTX-1719 is a potent and selective inhibitor of the PRMT5/MTA complex with an IC50 value of <10 nM against PRMT5/MTAMTAPDELSDMA cell lines.Cost-effective and quality-assured.Formula:C23H18ClFN6O2Purity:98.27% - 99.18%Color and Shape:SolidMolecular weight:464.88Ref: TM-T40254
1mg379.00€5mg740.00€10mg1,005.00€25mg1,679.00€50mg2,355.00€100mg3,437.00€1mL*10mM (DMSO)758.00€FHD-286
CAS:FHD-286 is an inhibitor of BRM/BRG1 ATPase and can be used for studies on the treatment of BAF-related disorders such as acute myeloid leukemia.Formula:C24H30N6O6S2Purity:98.7%Color and Shape:SolidMolecular weight:562.66Ref: TM-T9749
1mg145.00€5mg354.00€10mg550.00€25mg747.00€50mg938.00€100mg1,293.00€500mg2,593.00€1mL*10mM (DMSO)378.00€dCBP-1
CAS:dCBP-1 selectively degrades p300/CBP via CRBN, killing multiple myeloma cells.Formula:C51H63F2N11O10Purity:98.21% - 99.12%Color and Shape:SolidMolecular weight:1028.11
