Chromatin/Epigenetics
Chromatin/epigenetics inhibitors are compounds that modulate the structure and function of chromatin or interfere with epigenetic modifications, such as DNA methylation and histone modification. These inhibitors are essential tools for studying gene expression regulation and the role of epigenetics in diseases like cancer, neurological disorders, and developmental abnormalities. By targeting epigenetic processes, these inhibitors can alter gene expression patterns and offer new therapeutic avenues. At CymitQuimica, we provide a wide selection of high-quality chromatin/epigenetics inhibitors to support your research in molecular biology, genetics, and epigenetics.
Subcategories of "Chromatin/Epigenetics"
Products of "Chromatin/Epigenetics"
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BETd-260
CAS:BETd-260, a PROTAC linked by a Cereblon ligand and a BET ligand, has an inhibitory effect on BRD4 protein in leukemic cell lines.Formula:C43H46N10O6Purity:96.76%Color and Shape:SolidMolecular weight:798.89AU-15330
CAS:AU-15330 is a proteolytic targeting chimera (PROTAC) that simultaneously targets SMARCA4, SMARCA2, and PBRM1 for degradation and exhibits cytotoxicity in H3.3K27M cells but not in H3 wild-type cells. Cost-effective and quality-assured.Formula:C39H49N9O5SPurity:100% - 98.21%Color and Shape:SolidMolecular weight:755.93Albendazole
CAS:Albendazole (SKF-62979) is used as a drug indicated for the treatment of a variety of worm infestations.Formula:C12H15N3O2SPurity:98.21% - 98.76%Color and Shape:Colorless Crystals SolidMolecular weight:265.33CPI-169 racemate
CAS:CPI-169 racemate (CPI 169) is a potent, and selective EZH2 inhibitor with IC50 of 0.24 nM, 0.51 nM, and 6.1 nM for EZH2 WT, EZH2 Y641N, and EZH1, respectively.Formula:C27H36N4O5SPurity:99.59%Color and Shape:SolidMolecular weight:528.66Ref: TM-T6809
1mg56.00€2mg79.00€5mg125.00€10mg172.00€25mg376.00€50mg560.00€100mg797.00€1mL*10mM (DMSO)145.00€S-Ruxolitinib
CAS:S-Ruxolitinib can be used in related research in the field of life sciences. Its product number is T3066 and CAS number is 1160597-27-2.Formula:C17H18N6Purity:98%Color and Shape:SolidMolecular weight:306.37MAT2A inhibitor 2
CAS:MAT2A inhibitor 2 is an inhibitor of methionine adenosyltransferase 2A (MAT2A).Formula:C18H24ClN3O3Purity:99.52%Color and Shape:SolidMolecular weight:365.85Ref: TM-T11950
1mg51.00€5mg106.00€10mg169.00€25mg298.00€50mg445.00€100mg655.00€500mg1,359.00€1mL*10mM (DMSO)119.00€Venadaparib
CAS:Venadaparib, a PARP inhibitor (IC50: 1.4/1.0 nM for PARP1/2), is orally active, selective, not affecting PARP-5, used in tumor studies.Formula:C23H23FN4O2Purity:98.47%Color and Shape:SolidMolecular weight:406.45Ref: TM-T9430
1mg48.00€2mg63.00€5mg96.00€10mg144.00€25mg283.00€50mg464.00€100mg680.00€1mL*10mM (DMSO)96.00€PROTAC BRD9 Degrader-6
CAS:PROTAC BRD9 Degrader-6, with an IC50 value of 0.13 nM, is a potent degrader of BRD9 suitable for research on BAF complex-related disorders [1].Formula:C47H56N8O6Purity:98%Color and Shape:SolidMolecular weight:829(Rac)-BAY1238097
CAS:(Rac)-BAY1238097 is a inhibitor of BET(IC50 of 1.02 μM for BRD4),used in cancer research.Formula:C25H33N5O3Purity:98%Color and Shape:SolidMolecular weight:451.56MS023 dihydrochloride
CAS:MS023 dihydrochloride (MS023 2HCl) is a human type I protein arginine methyltransferase inhibitor with antitumour activity for the study of breast cancer.Formula:C17H27Cl2N3OPurity:99.52%Color and Shape:SolidMolecular weight:360.32LNK01004
CAS:LNK01004 is a JAK inhibitor that exhibits potent inhibitory effects on JAK1 (IC50: 10 nM), JAK2 (IC50: ＜0.51 nM), and TYK2 (IC50: 1.0 nM). It can concurrently inhibit multiple cytokine-induced p-STAT signaling pathways and is applicable for research on diseases such as atopic dermatitis.Formula:C26H31N7O2Color and Shape:SolidMolecular weight:473.57Londamocitinib
CAS:Londamocitinib (JAK1-IN-7) is a selective and potent JAK1 inhibitor with anti-inflammatory activity.Formula:C28H31F2N7O4SPurity:99.47%Color and Shape:SolidMolecular weight:599.65Ref: TM-T11706
1mg180.00€5mg439.00€10mg597.00€25mg905.00€50mg1,169.00€100mg1,568.00€1mL*10mM (DMSO)567.00€IDF-11774
CAS:IDF-11774 is a HIF-1 inhibitor.It reduces hif-1α HRE luciferase activity (IC50 = 3.65 μM).Formula:C23H32N2O2Purity:98.05%Color and Shape:SolidMolecular weight:368.51PFI-2
CAS:PFI-2 is an effective, specific and cell-active lysine methyltransferase SETD7 inhibitor (Ki/IC50: 0.33/2 nM), 1000-fold selectivity over otherFormula:C23H25F4N3O3SPurity:99.38%Color and Shape:SolidMolecular weight:499.52Methylstat
CAS:Methylstat is a methyl ester prodrug of a Jumonji C domain-containing histone demethylase (JMJD) inhibitor that has favorable cell permeability.Formula:C28H31N3O6Purity:98.34% - 98.34%Color and Shape:SolidMolecular weight:505.56NU 9056
CAS:NU 9056 is an effective and selective inhibitor of KAT5 histone acetyltransferase with an IC50 of 2 µM.Formula:C6H4N2S4Purity:95.36%Color and Shape:SolidMolecular weight:232.37Gentiakochianin
CAS:Gentiakochianin (Swertianine), vasodilatory, induce G(2)/M phase and inhibits proliferation, reduces oxLDL-induced , inhibits ROS s,up-regulated Akt/CREB/eNOS.Formula:C14H10O6Purity:98.97%Color and Shape:SolidMolecular weight:274.23E-7386
CAS:E-7386 is an oral active CBP/ -catenin modulator.Formula:C39H48FN9O4Purity:98.92% - 99%Color and Shape:SolidMolecular weight:725.85Ref: TM-T11136
1mg87.00€5mg255.00€10mg376.00€25mg647.00€50mg920.00€100mg1,225.00€1mL*10mM (DMSO)399.00€MLN8054
CAS:MLN8054 is a potent and selective Aurora A kinase inhibitor with an IC50 of 4 nM.Formula:C25H15ClF2N4O2Purity:98.07% - 98.26%Color and Shape:SolidMolecular weight:476.86Ref: TM-T6315
1mg52.00€2mg71.00€5mg88.00€10mg127.00€25mg233.00€50mg376.00€100mg567.00€1mL*10mM (DMSO)93.00€CPI-637
CAS:CPI-637 is a selective and cell-active benzodiazepinone CBP/EP300 bromodomain inhibitor.Formula:C22H22N6OPurity:99.75% - 99.91%Color and Shape:SolidMolecular weight:386.45
