Chromatin/Epigenetics
Chromatin/epigenetics inhibitors are compounds that modulate the structure and function of chromatin or interfere with epigenetic modifications, such as DNA methylation and histone modification. These inhibitors are essential tools for studying gene expression regulation and the role of epigenetics in diseases like cancer, neurological disorders, and developmental abnormalities. By targeting epigenetic processes, these inhibitors can alter gene expression patterns and offer new therapeutic avenues. At CymitQuimica, we provide a wide selection of high-quality chromatin/epigenetics inhibitors to support your research in molecular biology, genetics, and epigenetics.
Subcategories of "Chromatin/Epigenetics"
Products of "Chromatin/Epigenetics"
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VPC-70063
CAS:VPC-70063 (Thiourea, N-[3,5-bis(trifluoromethyl)phenyl]-N'-(phenylmethyl)-) is an inhibitor of c-Myc-MAX.Formula:C16H12F6N2SPurity:99.93%Color and Shape:SolidMolecular weight:378.34Ref: TM-T60019
1mg51.00€5mg106.00€10mg160.00€25mg283.00€50mg406.00€100mg592.00€200mg835.00€1mL*10mM (DMSO)137.00€PARP10-IN-2
CAS:PARP10-IN-2 is a potent inhibitor of PARP10, a mono-ADP-ribosyltransferase, with an IC50 value of 3.64 μM for human PARP10.PARP10-IN-2 also inhibited PARP2 andFormula:C14H10N2O2Purity:99.68%Color and Shape:SolidMolecular weight:238.24PF-CBP1 hydrochloride
CAS:PF-CBP1 HCl selectively inhibits CREBBP bromodomain (IC50: 125 nM) and p300 (IC50: 363 nM).Formula:C29H37ClN4O3Purity:97.11% - 99.02%Color and Shape:SolidMolecular weight:525.08Eleven-Nineteen-Leukemia Protein IN-2
CAS:Eleven-Nineteen-Leukemia Protein IN-2 (compound 23), an ENL inhibitor, exhibits an IC50 of 10.7 nM and is utilized for leukemia research [1].Formula:C22H23N5O2Purity:98%Color and Shape:SolidMolecular weight:389.45PF-06821497
CAS:PF-06821497 is a selective inhibitor of EZH2 with significant tumor growth inhibition.Cost-effective and quality-assured.Formula:C22H24Cl2N2O5Purity:97.88%Color and Shape:SolidMolecular weight:467.34Citric acid trilithium salt tetrahydrate
CAS:Citric acid trilithium salt tetrahydrate (Lithium citrate tribasic tetrahydrate) , the active component of Lithium, is a medicine used in the therapy ofFormula:C6H13Li3O11Purity:≥95%Color and Shape:White Crystalline PowderMolecular weight:281.98CF53
CAS:CF53: potent, selective oral BET inhibitor; Ki <1 nM, Kd 2.2 nM, IC50 2 nM for BRD4 BD1; high affinity for BRD2/3/4/BRDT; effective anti-tumor agent.Formula:C24H25N7O2Purity:99.72%Color and Shape:SolidMolecular weight:443.5Ref: TM-T10773
1mg96.00€5mg212.00€10mg316.00€25mg510.00€50mg695.00€100mg940.00€1mL*10mM (DMSO)226.00€CEP-33779
CAS:CEP-33779 is a novel and selective inhibitor of JAK2 with an IC50 of 1.8±0.6 nM.Formula:C24H26N6O2SPurity:98.81% - ≥95%Color and Shape:SolidMolecular weight:462.57Ref: TM-T6122
1mg46.00€2mg59.00€5mg87.00€10mg144.00€25mg245.00€50mg376.00€100mg560.00€500mg1,216.00€1mL*10mM (DMSO)97.00€GSK484 hydrochloride
CAS:GSK484 hydrochloride (GTPL8577) is a reversible peptidyl-arginine deiminase 4 (PAD4) inhibitor.Cost-effective and quality-assured.Formula:C27H32ClN5O3Purity:98.32% - 99.62%Color and Shape:SolidMolecular weight:510.03Ref: TM-TQ0067
1mg74.00€5mg156.00€10mg227.00€25mg457.00€50mg655.00€100mg933.00€1mL*10mM (DMSO)167.00€CBP-IN-1
CAS:CBP-IN-1 (compound 12) acts as a potent CBP inhibitor exhibiting an IC50 of 1.5 nM and additionally suppresses CBP BRET and BRD4(1) with IC50 values of 690 nMFormula:C27H33F2N7OPurity:98%Color and Shape:SolidMolecular weight:509.59RBN-3143
CAS:RBN-3143: potent PARP14 inhibitor (IC50= 4 nM), blocks ADP-ribosylation, may treat lung inflammation.Formula:C22H28FN3O4SPurity:98.64%Color and Shape:SoildMolecular weight:449.54Ref: TM-T67844
1mg95.00€5mg202.00€10mg298.00€25mg507.00€50mg730.00€100mg1,026.00€500mg2,052.00€1mL*10mM (DMSO)224.00€Vafidemstat
CAS:Vafidemstat (ORY-2001) is a lysine-histone demethylase (LSD1)/MAO-B inhibitor for the study of neurological disorders.Formula:C19H20N4O2Purity:99.53%Color and Shape:SolidMolecular weight:336.395-Methyl-2'-deoxycytidine
CAS:5-Methyl-2'-deoxycytidine (5MedCyd) is a pyrimidine nucleoside that when incorporated into single-stranded DNA can act in cis to signal de novo.Formula:C10H15N3O4Purity:99.18% - 99.69%Color and Shape:SolidMolecular weight:241.24LSD1-IN-20
CAS:LSD1-IN-20: Dual LSD1/G9a inhibitor, Ki 0.44/0.68 μM; hampers THP-1, MDA-MB-231 cell growth with IC50 0.51/1.60 μM at 72h.Formula:C27H38N6O2Purity:98.21% - 98.72%Color and Shape:SolidMolecular weight:478.63Phthalazinone pyrazole
CAS:Phthalazinone pyrazole: a potent, selective oral Aurora-A kinase inhibitor, overexpressed in tumors with oncogenic activity.Formula:C18H15N5OPurity:97.03%Color and Shape:SolidMolecular weight:317.34Ref: TM-T21981
1mg64.00€2mg96.00€5mg145.00€10mg212.00€25mg353.00€50mg532.00€100mg792.00€200mg1,064.00€PROTAC BRD4-DCAF1 degrader-1
CAS:PROTACBRD4-DCAF1 degrader-1 (I-907) is a PROTAC degrader targeting BRD4-DCAF1, exhibiting a DC50 range of 10~100 nM.Formula:C60H64Cl2F2N8O9SColor and Shape:SolidMolecular weight:1182.17Talazoparib tosylate
CAS:PF-3882845 is an MR antagonist that binds to the progesterone receptor (PR) and is used in the study of endocrine disorders and urogenital disorders.Formula:C26H22F2N6O4SPurity:99.79%Color and Shape:SolidMolecular weight:552.55Ref: TM-T16979
2mg42.00€5mg62.00€10mg88.00€25mg135.00€50mg188.00€100mg311.00€200mg432.00€1mL*10mM (DMSO)74.00€Ref: TM-T5S2358
1mg57.00€2mg81.00€5mg111.00€10mg160.00€25mg263.00€50mg378.00€100mg558.00€200mg797.00€1mL*10mM (DMSO)123.00€Aurora Kinases-IN-4
CAS:Aurora Kinases-IN-4 (Compound 11c) is a covalent, ATP-competitive inhibitor of aurora kinase A with an IC50 value of 1.7 nM.Formula:C26H28N8OPurity:98%Color and Shape:SolidMolecular weight:468.55ZZM-1220
ZZM-1220, a covalent inhibitor of histone lysine methyltransferase G9a/GLP, exhibits IC50 values of 458 nM for G9a and 924 nM for GLP.Formula:C25H29N5O3Purity:98%Color and Shape:SolidMolecular weight:447.53
