TLR
Toll-like receptors (TLRs) are a class of proteins that play a critical role in the innate immune system by recognizing pathogen-associated molecular patterns (PAMPs) and initiating immune responses. TLRs are involved in detecting a wide range of pathogens, including bacteria, viruses, and fungi, and are essential for the activation of inflammatory signaling pathways. Dysregulation of TLR signaling is associated with chronic inflammatory diseases, autoimmune disorders, and cancer. At CymitQuimica, we offer a variety of high-quality TLR modulators to support your research in innate immunity, inflammation, and infectious disease.
Products of "TLR"
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MD2-TLR4-IN-1
CAS:MD2-TLR4-IN-1 is a myeloid differentiation protein 2/toll-like receptor 4 (MD2-TLR4) complex inhibitor.Formula:C22H14Cl2N4OPurity:97.74%Color and Shape:SolidMolecular weight:421.28Ref: TM-T7672
1mg62.00€5mg135.00€10mg212.00€25mg363.00€50mg510.00€100mg672.00€200mg905.00€1mL*10mM (DMSO)149.00€TLR3-IN-1
CAS:TLR3-IN-1 (CU CPT 4a) is a selective TLR3 inhibitor. It can inhibit TLR3/dsRNA complex-mediated downstream signaling pathways and inhibit the TNF-α and IL-1β.Formula:C18H13ClFNO3SPurity:98.56%Color and Shape:SolidMolecular weight:377.82Ref: TM-T22698
1mg52.00€2mg74.00€5mg114.00€10mg187.00€25mg398.00€50mg593.00€100mg845.00€500mg1,700.00€1mL*10mM (DMSO)126.00€MC-Val-Cit-PAB-Amide-TLR7 agonist 4 Conjugate
CAS:MC-Val-Cit-PAB-Amide-TLR7 agonist 4 Conjugate is a conjugate formed by linking MC-Val-Cit-PAB-Amide and TLR7 agonist 4, useful for cancer research.Formula:C52H72N12O11Purity:97.70%Color and Shape:SolidMolecular weight:1041.2LHC-165
CAS:LHC-165 is an agonist of TLR7. It also has the potential to treat solid tumors.Formula:C29H32F2N3O7PPurity:98%Color and Shape:SolidMolecular weight:603.55Robinin
CAS:Robinin: a kaempferol-derived flavone glycoside with antibacterial, diuretic traits; minimal effect on Colo 320 MDR1/LRP resistance; detected in MCF-7 cells.Formula:C33H40O19Purity:98.78% - 99.13%Color and Shape:SolidMolecular weight:740.66Polyinosinic-polycytidylic acid
CAS:Polyinosinic-polycytidylic acid (Poly(I:C)) is a synthetic double-stranded RNA (dsRNA) analog and an immunostimulant that acts as the most potent IFN inducer.Formula:(C10H13N4O8P)x·(C9H14N3O8P)xPurity:90%Color and Shape:SolidMolecular weight:671.4CL264
CAS:CL264, a selective agonist of TLR7, can be used in studies about innate immune signals.Formula:C19H23N7O4Purity:97.14%Color and Shape:SolidMolecular weight:413.43Ref: TM-T10833
1mg51.00€5mg116.00€10mg192.00€25mg304.00€50mg420.00€100mg560.00€200mg755.00€1mL*10mM (DMSO)128.00€3M-011
CAS:3M-011: potent TLR7/8 agonist, cytokine inducer, enhances radiotherapy, fights H3N2, and has anti-tumor effects.Formula:C18H25N5O3SPurity:98%Color and Shape:SolidMolecular weight:391.49IAXO-102
CAS:IAXO-102 is a TLR4 antagonist that negatively regulates TLR4 signaling.Formula:C35H71NO5Purity:98.17%Color and Shape:SolidMolecular weight:585.94Bropirimine
CAS:Bropirimine (U-54461) (U-54461) is a biological response modifier that is thought to act through the induction of lymphokines.Formula:C10H8BrN3OPurity:99.01%Color and Shape:SolidMolecular weight:266.09TL8-506
CAS:TL8-506 is a selective and potent TLR8 agonist that induces cytokine and chemokine production.TL8-506 alleviates inflammatory and autoimmune diseases.Formula:C20H17N3O2Purity:95%Color and Shape:SolidMolecular weight:331.37MC-Val-Cit-PAB-Amide-TLR7 agonist 4 TFA
MC-Val-Cit-PAB-Amide-TLR7 agonist 4 TFA is the trifluoroacetate form of MC-Val-Cit-PAB-Amide-TLR7 agonist 4,a HER2-TLR7 and HER2- TLR8 immune agonist complexes.Formula:C54H73F3N12O13Purity:99.67%Color and Shape:SolidMolecular weight:1155.22Ref: TM-T74468L
1mg201.00€5mg497.00€10mg701.00€25mg1,094.00€50mg1,508.00€100mg1,931.00€200mg2,637.00€BBIQ
CAS:BBIQ is a powerful vaccine adjuvant that enhances innate immune responses and a potent and selectively toll-like receptor 7 (TLR7) agonist with an EC50 of 59.1Formula:C21H22N4Purity:98.02%Color and Shape:SolidMolecular weight:330.43Motolimod
CAS:Motolimod (VTX-378) (VTX-2337) is an effective and specific Toll-like receptor (TLR) 8 agonist (EC50: 100 nM), > 50-fold selectivity over TLR7.Formula:C28H34N4O2Purity:97.43% - 99.27%Color and Shape:SolidMolecular weight:458.6TLR7 agonist 3
CAS:TLR7 agonist 3 is a Toll-like receptor 7 (TLR7) agonist that has anticancer activity and is used in the study of diseases of the immune system.Formula:C18H24N4OPurity:99.27%Color and Shape:SolidMolecular weight:312.41Ref: TM-T38614
1mg115.00€5mg274.00€10mg455.00€25mg748.00€50mg1,064.00€100mg1,415.00€1mL*10mM (DMSO)303.00€VB 201
CAS:VB 201 is a small molecule of oxidized phospholipids with anti-inflammatory activity that can be used to study atherosclerosis.Formula:C29H60NO8PPurity:100%Color and Shape:SolidMolecular weight:581.76E6446 dihydrochloride
CAS:E6446 dihydrochloride is a novel synthetic antagonist for nucleic acid-sensing TLRs; potently suppressed DNA stimulation of HEK:TLR9 cells with IC50 of 10 nM.Formula:C27H37Cl2N3O3Purity:98.44%Color and Shape:SolidMolecular weight:522.51Ref: TM-T4068
1mg107.00€2mg169.00€5mg304.00€10mg376.00€25mg628.00€50mg895.00€100mg1,216.00€200mg1,634.00€1V209
CAS:1V209 (TLR7 agonist T7) is a Toll-like receptor 7 (TLR7) agonist and has anti-tumor effects.Formula:C16H17N5O5Purity:99.61%Color and Shape:SolidMolecular weight:359.34Ref: TM-T8316
1mg38.00€5mg79.00€10mg126.00€25mg271.00€50mg395.00€100mg560.00€200mg797.00€1mL*10mM (DMSO)87.00€CU-CPT9b
CAS:CU-CPT9b (TLR8-specific antagonist 1) is an antagonist of toll-like receptor 8 (TLR8; Kd = 21 nM).Formula:C16H13NO2Purity:98.10%Color and Shape:SolidMolecular weight:251.28Chloranil
CAS:Chloranil (tetrachloro-p-benzoquinone) induces inflammation and neurological dysfunction and can be used to model inflammation in mice.Formula:C6Cl4O2Purity:99.38%Color and Shape:SolidMolecular weight:245.88
