Sodium Channel
Sodium channels are essential membrane proteins that allow the passage of sodium ions (Na+) across the cell membrane, generating and propagating electrical signals in neurons, muscle cells, and other excitable tissues. These channels are vital for the initiation and conduction of action potentials, making them crucial in processes such as nerve impulse transmission, muscle contraction, and cardiac function. Dysregulation of sodium channels can lead to neurological disorders, arrhythmias, and chronic pain conditions. At CymitQuimica, we provide a variety of sodium channel modulators to support your research in neurobiology, cardiology, and pain management.
Products of "Sodium Channel"
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Fosphenytoin disodium
CAS:Fosphenytoin disodium (ACC-9653) is a prodrug of phenytoin that is rapidly converted to phenytoin, a voltage-gated sodium channel blockerFormula:C16H13N2Na2O6PPurity:99.97%Color and Shape:White Crystalline PowderMolecular weight:406.24Rilmakalim
CAS:Rilmakalim is a potassium channel opener. Rilmakalim shows antivasoconstrictor effect.Formula:C21H23NO5SPurity:100% - 99.63%Color and Shape:SolidMolecular weight:401.48Ambroxol Hydrochloride
CAS:Controlled ProductFormula:C13H18Br2N2O·ClHColor and Shape:White To Off-WhiteMolecular weight:414.56Suzetrigine
CAS:Suzetrigine (VX-548) is an oral NaV1.8 inhibitor with analgesic properties for acute pain research.Formula:C21H20F5N3O4Purity:98.08% - 99.27%Color and Shape:SolidMolecular weight:473.39Ref: TM-T69552
1mg58.00€5mg114.00€10mg170.00€25mg266.00€300g129,112.00€50mg457.00€100mg800.00€1mL*10mM (DMSO)118.00€Benzonatate (PEGn)
CAS:Benzonatate (PEGn) is a unique non-narcotic cough suppressant featuring sodium channel blocking properties and anesthetic effects on respiratory tract stretch receptors.Formula:(C2H4O)nC12H17NO2Color and Shape:SolidRanolazine dihydrochloride
CAS:Ranolazine 2HCl, an antianginal, treats arrhythmia by inhibiting sodium current without changing blood pressure or heart rate.Formula:C24H35Cl2N3O4Purity:100% - 99.96%Color and Shape:White Crystalline PowderMolecular weight:500.46Carbamazepine
CAS:Carbamazepine: a tricyclic with anticonvulsant and analgesic effects, treats trigeminal neuralgia.Formula:C15H12N2OPurity:99.79% - 99.88%Color and Shape:SolidMolecular weight:236.27A-803467
CAS:A-803467 is a selective NaV1.8 channel blocker.Formula:C19H16ClNO4Purity:96.94% - 98%Color and Shape:SolidMolecular weight:357.79Myomodulin
CAS:Myomodulin is a neuropeptide present in molluscs, insects, and gastropods.Myomodulin is present in two identified aplysia neurons that contain myomodulin A theFormula:C36H67N11O8S2Purity:98%Color and Shape:SolidMolecular weight:846.12(R)-Duloxetine
CAS:(R)-Duloxetine, an isomer of Duloxetine, induces tonic and use-dependent blockade of neuronal Na+ channels. This compound is utilized in pain research.Formula:C18H19NOSColor and Shape:SolidMolecular weight:297.42Mepivacaine-d3
CAS:Controlled ProductApplications An anti-inflammatory and analgesic agent. Anesthetic (local). References Reynolds, et al.: Br. J. Anaesth., 43, 33 (1971); Tullar, et al.: J. Med. Chem., 14, 891 (1971); Aberg, G., et al.: Acta Pharmacol. Toxicol., 31, 273 (1972);Formula:C15D3H19N2OColor and Shape:NeatMolecular weight:249.37Nav1.8-IN-4
CAS:Nav1.8-IN-4 is a potent Nav1.8 channel inhibitor with potential analgesic activity.Nav1.8-IN-4 can be used for pain and neurological related disorders.Formula:C20H14F4N2O3Purity:99.83%Color and Shape:SoildMolecular weight:406.33Ref: TM-T77693
1mg59.00€2mg85.00€5mg125.00€10mg188.00€25mg376.00€50mg612.00€100mg938.00€500mg1,882.00€N-(Methoxymethyl)-N-[(trimethylsilyl)methyl]benzenemethanamine (>90%)
CAS:Controlled ProductApplications N-(Methoxymethyl)-N-[(trimethylsilyl)methyl]benzenemethanamine is used in the synthesis of pyrrolidine derivatives as novel sodium channel blockers used to treat ischemic related ailments. References Seki, M. et al.: Bioorg. Med. Chem. Lett., 23, 4230 (2013);Formula:C13H23NOSiPurity:>90%Color and Shape:NeatMolecular weight:237.41RY785
CAS:RY785 is a potent and selective inhibitor of voltage-gated potassium channel such as KV2.2 (IC50 = 50 nM). RY785 may be used in pain relief studies.Formula:C21H20N4O2SPurity:98.04%Color and Shape:SolidMolecular weight:392.47Ref: TM-T12786
1mg51.00€5mg144.00€10mg235.00€25mg399.00€50mg560.00€100mg787.00€200mg1,093.00€1mL*10mM (DMSO)131.00€E 0747
CAS:E 0747 is an antiarrhythmic agent of class 1C type. E-0747 suppresses arrhythmia by inhibiting the Na channels of cardiac cells.Formula:C21H28ClN3O4Purity:95.01%Color and Shape:SolidMolecular weight:421.92Lidocaine-d6 Hydrochloride
CAS:Controlled ProductApplications Lidocaine-d6 Hydrochloride is the labeled analogue of Lidocaine Hydrochloride, a local anesthetic; antiarrhythmic (class IB). Long-acting, membrane stabilizing agent against ventricular arrhythmia. Originally developed as a local anesthetic. Not a dangerous good if item is equal to or less than 1g/ml and there is less than 100g/ml in the package References Duce, R., et al.: J. Pharmacol. Exp. Ther., 179, 580 (1971), Kronberg, G.H., et al.: J. Med. Chem., 16, 739 (1973), Groningsson, K., et al.: Anal. Profiles Drug Subs., 14, 207 (1985), Davies, P.S., et al.: Drugs, 64, 937 (2004),Formula:C14H17D6ClN2OColor and Shape:NeatMolecular weight:276.84GS967
CAS:GS967 is a potent, and selective inhibitor of cardiac late sodium current (late INa ).Formula:C14H7F6N3OPurity:100% - 99.62%Color and Shape:SolidMolecular weight:347.22Ref: TM-T2049
2mg35.00€5mg52.00€10mg79.00€25mg159.00€50mg284.00€100mg495.00€200mg718.00€500mg1,111.00€1mL*10mM (DMSO)58.00€Lidocaine
CAS:Lidocaine, an amide local anesthetic, reduces pain and inflammation by dampening ICAM-1, cytokines, and neutrophil influx.Formula:C14H22N2OPurity:98.35% - 99.95%Color and Shape:Needles From Benzene Or Alcohol SolidMolecular weight:234.34Besipirdine
CAS:Besipirdine (HP 749 free base) is a non-receptor-dependent cholinomimetic compound with alpha-adrenergic activity and cardiovascular activity.Formula:C16H17N3Purity:97% - 98.59%Color and Shape:SolidMolecular weight:251.33Olisutrigine bromide
CAS:Olisutrigine bromide is a sodium channel blocker used as an analgesic.Formula:C25H35BrN2Color and Shape:SolidMolecular weight:443.463
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