PDE
Phosphodiesterases (PDEs) are enzymes that hydrolyze cyclic nucleotides, such as cAMP and cGMP, into their inactive forms, playing a key role in regulating intracellular signaling pathways. PDE inhibitors are used in the treatment of various conditions, including cardiovascular diseases, erectile dysfunction, and respiratory disorders, due to their ability to modulate cyclic nucleotide levels. At CymitQuimica, we provide a range of PDE inhibitors to support your research in cell signaling, pharmacology, and therapeutic development.
Products of "PDE"
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Propentofylline
CAS:Propentofylline (Hextol) has neuroprotective, antiproliferative and anti-inflammatory activities and can be used in the study of Alzheimer's disease.Formula:C15H22N4O3Purity:99.11% - 99.42%Color and Shape:Off-White SolidMolecular weight:306.36Ref: TM-T19812
1mg69.00€5mg145.00€10mg212.00€25mg358.00€50mg527.00€100mg750.00€1mL*10mM (DMSO)157.00€cis-Tadalafil
CAS:Tadalafil: a carboline-based PDE5 inhibitor, treats erectile dysfunction, prostatic hyperplasia, and pulmonary hypertension.Formula:C22H19N3O4Purity:≥98%Color and Shape:SolidMolecular weight:389.4Anti-ALDH7A1 Antibody (3P955)
Anti-ALDH7A1 Antibody (3P955) is a Rabbit antibody targeting ALDH7A1. Anti-ALDH7A1 Antibody (3P955) can be used in WB,ELISA,IP.Color and Shape:Odour LiquidThioquinapiperifil dihydrochloride
CAS:Thioquinapiperifil dihydrochloride is a potent, selective PDE-5 inhibitor (IC50: 0.074 nM) for research.Formula:C24H29ClN6OSPurity:98.73%Color and Shape:SolidMolecular weight:485.05Ref: TM-T9773
1mg84.00€5mg178.00€10mg266.00€25mg434.00€50mg562.00€100mg787.00€200mg1,035.00€1mL*10mM (DMSO)205.00€Homo Sildenafil
CAS:Homo Sildenafil is an analog of Sildenafil, It acts as a phosphodiesterase inhibitor.Formula:C23H32N6O4SPurity:99.88%Color and Shape:White SolidMolecular weight:488.6Ref: TM-T8919
2mg42.00€5mg64.00€10mg92.00€25mg187.00€50mg281.00€100mg393.00€200mg552.00€1mL*10mM (DMSO)78.00€Ketotifen fumarate
CAS:Ketotifen fumarate (HC 20511 fumarate) is a cycloheptathiophene blocker of histamine H1 receptors and release of inflammatory mediators.Formula:C23H23NO5SPurity:99.25% - 99.73%Color and Shape:SolidMolecular weight:425.5Mardepodect
CAS:Mardepodect (PF-2545920) is a phosphodiesterase inhibitor selective for the PDE10A subtype with an IC50 of 0.37 nM, >1000-fold selectivity over PDE.Formula:C25H20N4OPurity:98.82% - 99.81%Color and Shape:SolidMolecular weight:392.45Ref: TM-T16499
1mg43.00€2mg55.00€5mg92.00€10mg150.00€25mg245.00€50mg365.00€100mg547.00€1mL*10mM (DMSO)92.00€Lirimilast
CAS:Lirimilast: oral PDE4 inhibitor (IC50: 49 nM), anti-inflammatory, treats asthma/COPD.Formula:C17H12Cl2N2O6SPurity:98%Color and Shape:SolidMolecular weight:443.26PDE10-IN-1
CAS:PDE10-IN-1 (SEP-0372814) is used for treating CNS and metabolic disorders.Formula:C21H19N7Purity:99.65%Color and Shape:SolidMolecular weight:369.42N-Methylbenzamide
CAS:N-Methylbenzamide is a potent phosphodiesterase 10A (PDE10A) inhibitor,with anti-cancer activity.Formula:C8H9NOPurity:99.83%Color and Shape:Physical Description Off-White Crystalline Solid (Ntp 1992)Molecular weight:135.16Anti-ALDH7A1 Antibody (5P692)
Anti-ALDH7A1 Antibody (5P692) is a Rabbit antibody targeting ALDH7A1. Anti-ALDH7A1 Antibody (5P692) can be used in FCM,ICC/IF.Color and Shape:Odour LiquidBAY 73-6691
CAS:BAY 73-6691 is an inhibitor of brain penetrant PDE9A.Formula:C15H12ClF3N4OColor and Shape:SolidMolecular weight:356.73Dasantafil
CAS:Dasantafil (SCH446132) is a small molecule phosphodiesterase-5A (PDE5A) inhibitor used to treat genitourinary disorders and study erectile dysfunction.Formula:C22H28BrN5O5Purity:98.64% - 99.16%Color and Shape:SolidMolecular weight:522.39Amino Tadalafil
CAS:Amino tadalafil is a potent phosphodiesterase 5 (PDE5) inhibitor.Formula:C21H18N4O4Purity:99.45%Color and Shape:White PowderMolecular weight:390.39TyK2-IN-2
CAS:TyK2-IN-2 is a selective inhibitor of TYK2 (IC50s: 7 nM, 0.1 μM, and 0.05 μM for TYK2 JH2, IL-23, and IFNα).Formula:C16H18N6OPurity:98%Color and Shape:SolidMolecular weight:310.35ATX inhibitor 1
CAS:ATX inhibitor 1 is a potent ATX inhibitor (IC50: 1.23 nM, FS-3 and 2.18 nM, bis-pNPP).Formula:C21H23Cl2N2O6PPurity:99.52%Color and Shape:SolidMolecular weight:501.3PF-8380
CAS:PF-8380 is an effective and orally available autotaxin inhibitor (IC50: 2.8 nM, in isolated enzyme assay; 101 nM, in the human whole blood).Formula:C22H21Cl2N3O5Purity:98.70% - 99.25%Color and Shape:SolidMolecular weight:478.33Vardenafil
CAS:Vardenafil (Vivanza) is an oral therapy for the treatment of erectile dysfunction.Formula:C23H32N6O4SPurity:99.88%Color and Shape:SolidMolecular weight:488.6Nauclefine
CAS:Nauclefine, a plant alkaloid, triggers cancer cell death through PDE3A-SLFN12, binding but not inhibiting PDE3A.Formula:C18H13N3OPurity:99.92%Color and Shape:SolidMolecular weight:287.32BAY 73-6691 racemate
CAS:BAY 73-6691 racemate (Rac-BAY 73-6691) is a phosphodiesterase 9A (PDE9A) inhibitor, useful for studying Parkinson’s disease.Formula:C15H12ClF3N4OColor and Shape:SolidMolecular weight:356.73
