PDE
Phosphodiesterases (PDEs) are enzymes that hydrolyze cyclic nucleotides, such as cAMP and cGMP, into their inactive forms, playing a key role in regulating intracellular signaling pathways. PDE inhibitors are used in the treatment of various conditions, including cardiovascular diseases, erectile dysfunction, and respiratory disorders, due to their ability to modulate cyclic nucleotide levels. At CymitQuimica, we provide a range of PDE inhibitors to support your research in cell signaling, pharmacology, and therapeutic development.
Products of "PDE"
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HA 155
CAS:HA 155 (Autotaxin Inhibitor IV) is a boronic acid-based compound, inhibiting ATX with IC50 of 5.7 nM by selectively binding to its catalytic threonine.Formula:C24H19BFNO5SPurity:98.92%Color and Shape:SolidMolecular weight:463.29PF-04447943
CAS:PF-04447943, a selective PDE9A inhibitor (IC50=12nM), may aid sickle cell anemia research with its anti-inflammatory properties.Formula:C20H25N7O2Purity:99.11% - 99.11%Color and Shape:SolidMolecular weight:395.46Naproxen etemesil
CAS:Naproxen, a COX-1/2 inhibitor, has IC50s of 8.72/5.15 μM. Its prodrug, naproxen etemesil, is lipophilic and converts to active form upon absorption.Formula:C17H20O5SPurity:98%Color and Shape:SolidMolecular weight:336.4CRT0273750
CAS:CRT0273750 regulates plasma LPA levels and is suitable for in vivo studies. CRT0273750 is an autotaxin (ATX) inhibitor with IC50 of 0.014 μM.Formula:C25H22ClF3N4O2Purity:99.49%Color and Shape:SolidMolecular weight:502.92Dazonone
CAS:Dazonone (Imidazo[2,1-b]quinazolin-2(3H)-one, 6-chloro-1,5-dihydro-3-methyl-) is a specific PDE III inhibitors.Formula:C11H10ClN3OPurity:99.21% - 99.67%Color and Shape:SolidMolecular weight:235.67Ref: TM-T9871
1mg77.00€5mg158.00€10mg225.00€25mg338.00€50mg475.00€100mg638.00€200mg845.00€1mL*10mM (DMSO)138.00€BIO-32546
CAS:BIO-32546 (S-isomer) is a highly potent regulator of autotaxin (ATX) with an IC50 value of 1 nM.Formula:C28H31F6NO3Purity:98.03%Color and Shape:SolidMolecular weight:543.54Ref: TM-T10545
1mg221.00€5mg550.00€10mg905.00€25mg1,890.00€50mg3,030.00€100mg4,874.00€1mL*10mM (DMSO)35.00€Milrinone
CAS:Milrinone (Win 47203) is a Phosphodiesterase 3 Inhibitor. The mechanism of action of milrinone is as a Phosphodiesterase 3 Inhibitor.Formula:C12H9N3OPurity:99.22% - 99.92%Color and Shape:SolidMolecular weight:211.22
