PDE
Phosphodiesterases (PDEs) are enzymes that hydrolyze cyclic nucleotides, such as cAMP and cGMP, into their inactive forms, playing a key role in regulating intracellular signaling pathways. PDE inhibitors are used in the treatment of various conditions, including cardiovascular diseases, erectile dysfunction, and respiratory disorders, due to their ability to modulate cyclic nucleotide levels. At CymitQuimica, we provide a range of PDE inhibitors to support your research in cell signaling, pharmacology, and therapeutic development.
Products of "PDE"
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Sildenafil Mesylate
CAS:Sildenafil Mesylate is a mesylate form of Sildenafil, an inhibitor of Phosphodiesterase 5.Formula:C22H30N6O4S·xCH4O3SPurity:99.84%Color and Shape:SolidMolecular weight:570.68Roflumilast N-oxide
CAS:Roflumilast N-oxide is an inhibitor of PDE type 4.Formula:C17H14Cl2F2N2O4Purity:99.55% - 99.65%Color and Shape:SolidMolecular weight:419.21Ref: TM-T4462
1mg35.00€2mg52.00€5mg74.00€10mg99.00€25mg170.00€50mg274.00€100mg350.00€500mg840.00€1mL*10mM (DMSO)69.00€PAT-048
CAS:PAT-048 is an effective and selective autotaxin inhibitor.Formula:C22H18ClF2N3O2SPurity:98%Color and Shape:SolidMolecular weight:461.912-(Hydroxymethyl)pyridine
CAS:2-(Hydroxymethyl)pyridine (Piconol) is an intermediate for the synthesis of the stimulant laxative bisacodyl, and as a pyridinol with hypoglycemic activity.Formula:C6H7NOPurity:99.79%Color and Shape:Clear Light Yellow To Orange Liquid LiquidMolecular weight:109.13Zaprinast
CAS:Zaprinast is a cGMP-selective phosphodiesterase (PDE) inhibitor and a GPR35 agonist.Formula:C13H13N5O2Purity:99.73% - 99.77%Color and Shape:White To Off White PowderMolecular weight:271.27Cilostamide
CAS:Cilostamide (OPC3689) is a selective phosphodiesterase (PDE)3A and PDE3B inhibitor(IC50 values of 27 and 50 nM, respectively)Formula:C20H26N2O3Purity:98.87%Color and Shape:White To Off-White SolidMolecular weight:342.43Irsogladine
CAS:Irsogladine (Dicloguamine) is an anti-ulcer agent that promotes gap junction intercellular communication via M1 muscarinic acetylcholine receptor binding.Formula:C9H7Cl2N5Purity:99.74% - 99.91%Color and Shape:White Or Colorless Crystal Or Crystalline Powder Odorless Slightly BitterMolecular weight:256.09uk-50001
CAS:UK-50001 is a PDE4 inhibitor for treating inflammation, allergies, respiratory issues, and wounds.Formula:C26H24F3N3O4Purity:99.90%Color and Shape:SolidMolecular weight:499.48Ref: TM-T67815
1mg159.00€5mg380.00€10mg570.00€25mg912.00€50mg1,216.00€100mg1,663.00€500mg3,315.00€1mL*10mM (DMSO)470.00€AWD 12-281
CAS:AWD 12-281 is a PDE4 inhibitor with anti-inflammatory activity and bronchodilator activity for the study of chronic obstructive pulmonary disease (COPD).Formula:C22H14Cl2FN3O3Purity:99.55% - 99.95%Color and Shape:SolidMolecular weight:458.27Mopidamol
CAS:Mopidamol (RA 233) is a phosphodiesterase inhibitor, a dipyridamole derivative, with anticancer activity that prevents retinal vascular defects in experimentalFormula:C19H31N7O4Purity:99.42% - 99.51%Color and Shape:SolidMolecular weight:421.49Deltasonamide 2 hydrochloride
Deltasonamide 2 hydrochloride is a competitive high-affinity PDEδ inhibitor with a Kd of approximately 385 pM.Formula:C30H40Cl2N6O4S2Purity:98%Color and Shape:SolidMolecular weight:683.71MBCQ
CAS:MBCQ is an inhibitor of cGMP-specific phosphodiesterase PDE5.Formula:C16H12ClN3O2Purity:99.45%Color and Shape:SolidMolecular weight:313.74Ref: TM-T21965
5mg47.00€10mg80.00€25mg145.00€50mg233.00€100mg335.00€200mg467.00€1mL*10mM (DMSO)49.00€Tofimilast
CAS:Tofimilast (CP-325366), a PDE4 inhibitor, is used potentially for the treatment of asthma and chronic obstructive pulmonary disease.Formula:C18H21N5SPurity:99.94%Color and Shape:SolidMolecular weight:339.46Mirodenafil
CAS:Mirodenafil is a PDE-5 inhibitor developed for the treatment of erectile dysfunction.Formula:C26H37N5O5SPurity:99.89%Color and Shape:SolidMolecular weight:531.67Ref: TM-T16079
2mg35.00€5mg52.00€10mg79.00€25mg134.00€50mg210.00€100mg338.00€200mg497.00€1mL*10mM (DMSO)60.00€ONO-8430506
CAS:ONO-8430506 is an orally available, potent autotaxin (ATX)/ENPP2 inhibitor (IC90: 100 nM) that inhibits ATX activity in mouse plasma.Formula:C27H28FN3O3Purity:97.05%Color and Shape:SolidMolecular weight:461.53Ref: TM-T38759
1mg156.00€5mg368.00€10mg509.00€25mg770.00€50mg1,035.00€100mg1,396.00€200mg1,882.00€1mL*10mM (DMSO)409.00€Dipyridamole
CAS:Dipyridamole (Persantin) is a Platelet Aggregation Inhibitor. The physiologic effect of dipyridamole is by means of Decreased Platelet Aggregation.Formula:C24H40N8O4Purity:99.47% - 99.84%Color and Shape:SolidMolecular weight:504.63Z-HA155
CAS:Z-HA155 (CS-963) selectively and potently inhibits autotaxin with an IC50 of 5.7 nM.Formula:C24H19BFNO5SPurity:98.28%Color and Shape:SolidMolecular weight:463.29Ref: TM-T11533
1mg49.00€2mg65.00€5mg97.00€10mg154.00€25mg298.00€50mg487.00€100mg692.00€1mL*10mM (DMSO)106.00€Pimobendan
CAS:Pimobendan (UD-CG 115 BS) is a selective inhibitor of PDE3 (IC50: 0.32 μM).Formula:C19H18N4O2Purity:99.91%Color and Shape:SolidMolecular weight:334.37Ref: TM-T1708
2mg38.00€5mg60.00€10mg87.00€25mg162.00€50mg274.00€100mg406.00€500mg920.00€1mL*10mM (DMSO)66.00€Sulmazole
CAS:Sulmazole (AR-L 115-BS) is a small molecule Sulmazole is a small molecule cGMP-PDE inhibitor.Sulmazole is a competitive inhibitor of A1 adenosine receptors.Formula:C14H13N3O2SPurity:99.64%Color and Shape:SolidMolecular weight:287.34D159687
CAS:D159687 is a selective PDE4D inhibitor,had a procognitive profile as it improved memory in the novel object recognition test but had no antidepressant benefit.Formula:C21H19ClN2O2Purity:97.57%Color and Shape:SolidMolecular weight:366.84
