PPAR
Peroxisome Proliferator-Activated Receptors (PPARs) are a group of nuclear receptor proteins that function as transcription factors regulating the expression of genes involved in metabolism, particularly fatty acid storage and glucose metabolism. PPAR inhibitors are important tools for studying metabolic disorders such as diabetes, obesity, and cardiovascular diseases. These inhibitors can modulate lipid metabolism, insulin sensitivity, and inflammation, making them valuable in therapeutic research. At CymitQuimica, we offer a range of PPAR inhibitors to support your research in metabolic diseases, endocrinology, and drug development.
Products of "PPAR"
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CUDA
CAS:CUDA is an effective soluble cyclohydrolase inhibitor with IC50 of 11.1 nM and 112 nM for mouse sEH and human sEH, respectively.Formula:C19H36N2O3Purity:≥98%Color and Shape:SolidMolecular weight:340.5MSDC-0602K
CAS:MSDC-0602K, a Ps-TZD, targets PPARγ (IC50: 18.25 μM) and MPC, may help study fatty liver, lipid imbalance, inflammation, and insulin issues.Formula:C19H16KNO5SPurity:99.89%Color and Shape:SolidMolecular weight:409.5WAY-620472
CAS:WAY-620472 is a PPAR regulator that can be used to alter the lifespan of eukaryotes.Formula:C23H21N5OSPurity:98.07%Color and Shape:SolidMolecular weight:415.51AZD-9574
CAS:AZD-9574 is a selective inhibitor of PARP1 at the sites of SSBs.Formula:C21H22F2N6O2Purity:98.39% - 98.55%Color and Shape:SolidMolecular weight:428.44MK-0533
CAS:MK-0533 is a novel PPARγ partial agonist for the prevention of vascular endothelial dysfunction (VED) and VED-related cardiovascular disease.Formula:C28H24F3NO6Purity:99.64%Color and Shape:SoildMolecular weight:527.49Alpinetin
CAS:Alpinetin: antibacterial, anti-inflammatory, boosts HepG2 sensitivity to CDDP, fights hepatoma/pancreatic cancer, inhibits cell growth & activates caspases.Formula:C16H14O4Purity:98.39%Color and Shape:SolidMolecular weight:270.28Cloxiquine
CAS:Cloxiquine (Dermofongin) is a monohalogenated 8-hydroxyquinoline with activity against bacteria, fungi, and protozoa.Formula:C9H6ClNOPurity:99.87%Color and Shape:Light Yellow CrystalsMolecular weight:179.6LY518674
CAS:LY518674 (LY-674) decreases triglycerides and increases HDL-C and is used for the treatment of atherosclerosis.Formula:C23H27N3O4Purity:98.87%Color and Shape:SolidMolecular weight:409.48Ref: TM-T15821
1mg170.00€5mg359.00€10mg533.00€25mg847.00€50mg1,159.00€100mg1,568.00€1mL*10mM (DMSO)398.00€Anti-osteoporosis agent-10
Anti-osteoporosis agent-10 is an inhibitor of osteoporosis that suppresses the formation of osteoclasts with an IC50 of 0.042 μM. It also exhibits antagonistic activity towards PPARγ, with an EC50 value of 0.75 μM.Color and Shape:Odour SolidDarglitazone
CAS:Darglitazone (CP-86325) is a potent, selective agonist of PPAR-γ with antidiabetic actions.Formula:C23H20N2O4SPurity:99.19%Color and Shape:SolidMolecular weight:420.48Farglitazar
CAS:Farglitazar (GI-262570) is a PPAR-γ agonist and insulin sensitizer used in the study of diabetes.Formula:C34H30N2O5Purity:99.40% - 99.65%Color and Shape:SolidMolecular weight:546.61Rosiglitazone sodium
CAS:Rosiglitazone sodium is an effective and selective PPARγ activator, with EC50 values of 30 nM for PPARγ1, 100 nM for PPARγ2, and 60 nM for PPARγ. It also has an approximate Kd of 40 nM for PPARγ. Additionally, Rosiglitazone sodium acts as a regulator of TRP channels, inhibiting the activities of TRPM2 and TRPM3, while activating TRPC5.Formula:C18H18N3NaO3SColor and Shape:SolidMolecular weight:379.41PPAR α/PPARA Protein, Mouse, Recombinant (His)
PPAR alpha/PPARA Protein, Mouse, Recombinant (His) is expressed in E.Color and Shape:Lyophilized PowderMolecular weight:31.49 kDa (predicted)Saroglitazar
CAS:Saroglitazar (Lipaglyn) is an agonist of PPAR with EC50 values of 0.65 pM and 3 nM for PPARα and PPARγ.Formula:C25H29NO4SPurity:98.49%Color and Shape:SolidMolecular weight:439.57Glabrone
CAS:Glabrone shows antiviral activity against influenza virus.Formula:C20H16O5Purity:99.08% - 99.55%Color and Shape:SolidMolecular weight:336.34Imiglitazar
CAS:Imiglitazar (TAK559) is a potent PPAR-β/δ receptor agonist with hypoglycemic effects.Formula:C28H26N2O5Purity:97.33%Color and Shape:SolidMolecular weight:470.52Palmitelaidic Acid
CAS:Palmitelaidic Acid (trans-Palmitoleic acid) is one of the most abundant fatty acids in serum and tissue.Formula:C16H30O2Purity:99.36%Color and Shape:SolidMolecular weight:254.41SR 16832
CAS:SR 16832: Dual-site PPARγ inhibitor; outperforms GW 9662, T 0070907 in ligand binding, transcription inhibition.Formula:C17H12ClN3O4Purity:99.60%Color and Shape:SolidMolecular weight:357.75CRX000227
CAS:CRX000227 is a PPAR modulator suitable for researching metabolic and cell proliferative disorders [1].Formula:C25H24N4O2SPurity:98%Color and Shape:SolidMolecular weight:444.55Sulotroban potassium
Sulotroban potassium is a small molecule thromboxane A2 receptor (TXA2R) antagonist that can be used to study myocardial infarction and thrombosis.Formula:C16H16KNO5SPurity:98.04%Color and Shape:SoildMolecular weight:373.46
