AChR
Acetylcholine Receptor (AChR) inhibitors are compounds that block the activity of acetylcholine receptors, which are critical for neurotransmission in the central and peripheral nervous systems. AChRs play a vital role in muscle contraction, memory, and cognitive functions. Inhibitors of AChRs are used to study conditions such as myasthenia gravis, Alzheimer's disease, and other neurological disorders. By modulating AChR activity, these inhibitors can help unravel the complexities of cholinergic signaling in the brain. At CymitQuimica, we provide a range of AChR inhibitors to support your research in neuroscience, pharmacology, and neurodegenerative disease.
Products of "AChR"
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Oxotremorine M iodide
CAS:Oxotremorine M iodide (Oxotremorine methiodide) is an agonist of mAChR and potentiates NMDA receptors.Formula:C11H19IN2OPurity:98.75%Color and Shape:SolidMolecular weight:322.19LY2119620
CAS:LY2119620 is a specific, and allosteric agonist of human M2 and M4 muscarinic acetylcholine receptors.Formula:C19H24ClN5O3SPurity:99.7%Color and Shape:SolidMolecular weight:437.94UP202-56
CAS:UP202-56 is an adenosinergic agonist and is an adenosine analog.Formula:C33H37N7O4Purity:98%Color and Shape:SolidMolecular weight:595.69NBTGR
CAS:NBTGR is a potent nucleoside transport inhibitor(adenosine uptake ,Ki of 70 nM).Formula:C17H18N6O6SPurity:98%Color and Shape:SolidMolecular weight:434.43mAChr-in-1
CAS:mAChR-IN-1 is muscarinic cholinergic receptor(mAChR) antagonist (IC50=17 nM).Formula:C23H25IN2O2Purity:98%Color and Shape:SolidMolecular weight:488.36VU0467154
CAS:VU0467154 is a positive allosteric modulator of the M4 muscarinic acetylcholine receptor.Formula:C17H15F3N4O3S2Purity:98.05% - 98.28%Color and Shape:SolidMolecular weight:444.45Ref: TM-T17244
1mg52.00€5mg97.00€10mg139.00€25mg263.00€50mg444.00€100mg772.00€200mg1,026.00€1mL*10mM (DMSO)111.00€CHF5407
CAS:CHF5407(SVT-47060) is a potent and selective muscarinic M3 receptor antagonist with prolonged action at muscarinic receptors.CHF5407 has an effect onFormula:C27H25BrF4N2O3SPurity:100%Color and Shape:SolidMolecular weight:613.46V-11-0711 HCl
V-11-0711 HCl is a selective and highly effective choline kinase α (ChoKα) inhibitor that inhibits the catalytic activity of Chk.Formula:C27H36ClNO3Purity:100%Color and Shape:SolidMolecular weight:458.03Varenicline
CAS:Varenicline (CP 526555) is a selective partial agonist of the α4β2 nAChR and a full agonist of the α3β4 nAChR and α7 nAChR.Formula:C13H13N3Purity:99.76%Color and Shape:SolidMolecular weight:211.26Ref: TM-T4246L
2mg35.00€5mg52.00€10mg80.00€25mg144.00€50mg210.00€100mg329.00€200mg490.00€1mL*10mM (DMSO)58.00€CCMI
CAS:CCMI (AVL-3288) is a potent and selective modulator of α7 nAChR-positive allosteric.Formula:C19H15Cl2N3O2Purity:100%Color and Shape:SolidMolecular weight:388.25M4 mAChR agonist-1
CAS:M4 mAChR agonist-1 (4-Piperidinecarboxamide, 1-(5,6-dimethylthieno[2,3-d]pyrimidin-4-yl)-) is an effective agonist of M4 mAChR (EC50 >10 μM).Formula:C14H18N4OSPurity:98.25%Color and Shape:SolidMolecular weight:290.38SIB-1553A hydrochloride
CAS:SIB-1553A hydrochloride is a nicotinic acetylcholine receptor agonist and a selective neuronal nAChR ligandFormula:C13H20ClNOSPurity:99.47% - 99.71%Color and Shape:SolidMolecular weight:273.82Tacrine hydrochloride (hydrate)
CAS:Tacrine hydrochloride hydrate (Tetrahydroaminacrine) is a cholinesterase inhibitor that crosses the blood-brain barrier.Formula:C13H14N2·XHCl·XH2OPurity:99.01% - 99.89%Color and Shape:SolidMolecular weight:234.72PNU-282987
CAS:PNU-282987 is a selective α7 nicotinic acetylcholine receptor(α7 nAChR) agonist with Ki of 26 nM; no affinity for α1β1γδ and α3β4 nAChRs (IC50 ≥ 60 μM).Formula:C14H18Cl2N2OPurity:100% - 99.92%Color and Shape:SolidMolecular weight:301.21PF-03635659
CAS:PF-03635659: potent M3 antagonist, Ki=0.2 nM, long half-life, potential COPD treatment.Formula:C28H32N2O3Purity:98.05% - 99.83%Color and Shape:SolidMolecular weight:444.57Xanomeline oxalate
CAS:Xanomeline oxalate (LY246708), a potent SMRA, boosts phosphoinositide hydrolysis; key for Alzheimer's research.Formula:C16H25N3O5SPurity:98.22%Color and Shape:SolidMolecular weight:371.45Ref: TM-T13353
5mg38.00€10mg58.00€25mg105.00€50mg168.00€100mg259.00€200mg373.00€1mL*10mM (DMSO)42.00€SEN12333
CAS:SEN12333 is an α7 nicotinic acetylcholine receptor (nAChR) agonistFormula:C20H25N3O2Purity:99.02%Color and Shape:SolidMolecular weight:339.43Ref: TM-T23348
2mg39.00€5mg57.00€10mg95.00€25mg167.00€50mg269.00€100mg432.00€200mg622.00€1mL*10mM (DMSO)63.00€AChE/BChE-IN-10
CAS:AChE/BChE-IN-10 inhibits AChE/BChE (IC50: 0.176/0.47 μM), crosses the blood-brain barrier, and prevents Aβ-aggregation.Formula:C26H30N2O2Purity:99.55% - 99.75%Color and Shape:SoildMolecular weight:402.53Ref: TM-T61969
5mg44.00€10mg67.00€25mg126.00€50mg188.00€100mg306.00€200mg454.00€1mL*10mM (DMSO)54.00€N-0861 racemate
CAS:N-0861 racemate is the racemate of N-0861.Formula:C13H17N5Purity:98%Color and Shape:SolidMolecular weight:243.31Trospium chloride
CAS:Trospium chloride treats urinary incontinence without causing liver damage.Formula:C25H30ClNO3Purity:100% - 99.92%Color and Shape:White To Off-White PowderMolecular weight:427.964
