GPCR/G-Protein
GPCR/G-Protein inhibitors are compounds that target G-protein coupled receptors (GPCRs) and associated G-proteins, which play critical roles in transmitting signals from the outside to the inside of cells. These inhibitors are essential for studying the signaling pathways mediated by GPCRs, which are involved in numerous physiological processes, including sensory perception, immune response, and neurotransmission. GPCR inhibitors are also important in drug development, as many therapeutic agents target these receptors. At CymitQuimica, we offer a wide range of high-quality GPCR/G-Protein inhibitors to support your research in pharmacology, cell biology, and related fields.
Subcategories of "GPCR/G-Protein"
- 5-HT Receptor
- Adenosine Receptor
- Adrenergic Receptor
- Bombesin Receptor
- Bradykinin Receptor
- Cannabinoid Receptor
- CaSR
- Cholecystokinin
- CXCR
- Dopamine Receptor
- Endothelin Receptor
- Glucagon Receptor
- GNRH Receptor
- GPCR19
- GRK
- GTPase
- Hedgehog/Smoothened
- Histamine Receptor
- LPA Receptor
- Melatonin Receptor
- Opioid Receptor
- OX Receptor
- PAFR
- PKA
- S1P Receptor
- SGLT
- Sigma receptor
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Products of "GPCR/G-Protein"
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A3AR antagonist 5
CAS:A3AR antagonist 5 (Compound 16) acts as a selective antagonist for the human adenosine A3 receptor (human adenosine A3 receptor), with an affinity expressed as a pC value of 4.542 μM.Formula:C18H16N2O2SColor and Shape:SolidMolecular weight:324.40SB 243213 hydrochloride
CAS:SB 243213 hydrochloride is an orally active, selective and high-affinity antagonist of 5-hydroxytryptamine (5-HT)2C receptor(pKi of 9.37 and a pKb of 9.8).ItFormula:C22H20ClF3N4O2Purity:98%Color and Shape:SolidMolecular weight:464.87Ipsapirone
CAS:Ipsapirone is a partial agonist of 5-HT1A receptor and produces an inhibitory effect on 5-HT2 and the α1-adrenergic function at high doses.Formula:C19H23N5O3SPurity:99.01%Color and Shape:SolidMolecular weight:401.48Conopressin S acetate(111317-90-9 free base)
Conopressin S acetate(111317-90-9 free base) (Con-S acetate) is a natural product isolated from Conus striatus, shows high affinity with vasopressin V1bFormula:C43H77N17O12S2Purity:99.79%Color and Shape:SolidMolecular weight:1088.321-[(5-methylisoxazol-3-yl)methyl]piperazine
CAS:1-[(5-methylisoxazol-3-yl)methyl]piperazine (Piperazine, 1-[(5-methyl-3-isoxazolyl)methyl]- (9CI)) is a P2Y12 inhibitor.Formula:C9H15N3OPurity:95%Color and Shape:SolidMolecular weight:181.23E6130
CAS:E6130 may be effective in the treatment of inflammatory bowel disease and is a highly selective CX3CR1 regulator for oral administration.Formula:C28H37ClF3N3O3Color and Shape:SolidMolecular weight:556.06SLM6031434 HCl
CAS:SLM6031434 HCl (SLM-6031434 HCl) is a SphK2 inhibitor that reduces LPS-induced TNF伪 and IL-1尾 production.Formula:C22H31ClF3N5O2Purity:98%Color and Shape:SolidMolecular weight:489.96VUF11207 fumarate
CAS:VUF11207 fumarate is an agonist of CXCR7 and a high-potency ligand of CXCR7 (pKi: 8.1).Formula:C31H39FN2O8Purity:97.98%Color and Shape:SolidMolecular weight:586.65Ref: TM-T13324
1mg43.00€2mg55.00€5mg88.00€10mg137.00€25mg273.00€50mg472.00€100mg680.00€200mg947.00€1mL*10mM (DMSO)97.00€5-HT1A modulator 4
CAS:5-HT1A modulator 4 (Compound 1) is a ligand for the 5-HT receptor, with Ki values of 2.18 μM for 5-HT1A and 19.7 μM for 5-HT2A.Formula:C9H14N4Color and Shape:SolidMolecular weight:178.234Nemifitide diTFA
CAS:Nemifitide diTFA is a synthetic pentapeptide with antidepressant properties, resembling MIF, that crosses the blood-brain barrier.Formula:C37H45F7N10O10Purity:99.84%Color and Shape:SolidMolecular weight:922.8MD01-67
CAS:MD01-67 is a macrocyclic compound selectively targeting the neurotensin 2 receptor (NTS2), with a Ki of 2.9 nM. It exhibits analgesic activity and reduces tactile hypersensitivity in rat models of acute, sustained, and chronic inflammatory pain.Formula:C37H58N8O8Color and Shape:SolidMolecular weight:742.91GPR35 agonist 3
CAS:GPR35 agonist 3 is a synthetic GPR35 agonist used in the study of cancer, type 2 diabetes and cardiovascular disease.Formula:C12H9NO5SPurity:98.79%Color and Shape:SolidMolecular weight:279.27Talnetant
CAS:Talnetant (SB 223412) is a selective NK3 receptor antagonist that can penetrate the brain and modulate dopamine.Formula:C25H22N2O2Purity:97.88%Color and Shape:SolidMolecular weight:382.45Ref: TM-T7549
1mg43.00€2mg56.00€5mg92.00€10mg130.00€25mg265.00€50mg490.00€100mg743.00€1mL*10mM (DMSO)142.00€CXCR4 antagonist 10
CAS:CXCR4 antagonist10 (compound 21) is an effective CXCR4 inhibitor with an IC50 value of 7.8 nM. It plays a significant role in cancer research.Formula:C18H18N4O4Color and Shape:SolidMolecular weight:354.36Vapitadine dihydrochloride
CAS:Vapitadine dihydrochloride(R-129160 2HCl) is a novel, potent, selective and non-sedating compound with inhibitory effects on histamine H1.Formula:C17H22Cl2N4OPurity:100% - 99.92%Color and Shape:SolidMolecular weight:369.29Betahistine
CAS:Betahistine treats vertigo and balance issues in Ménière's disease; it's a histamine analog and H1 receptor agonist.Formula:C8H12N2Purity:97.92% - 99.87%Color and Shape:Yellowish Liquid Liquid LiquidMolecular weight:136.19Elagolix sodium
CAS:Elagolix sodium (NBI-56418 sodium) is a GnRH receptor (GnRHR) antagonist ( IC50 and Ki of 0.25 and 3.7 nM, respectively).Formula:C32H29F5N3NaO5Purity:99.71%Color and Shape:SolidMolecular weight:653.57Vofopitant dihydrochloride
CAS:Vofopitant dihydrochloride (GR 205171A) is a tachykinin NK1 receptor antagonist and a potential compound for the treatment of pathologic vomiting.Formula:C21H25Cl2F3N6OPurity:98.99%Color and Shape:SolidMolecular weight:505.36Ref: TM-T13329L
1mg99.00€5mg235.00€10mg376.00€25mg712.00€50mg1,064.00€100mg1,454.00€500mg2,822.00€1mL*10mM (DMSO)261.00€CID 2745687
CAS:CID 2745687 blocks human GPR35, countering cromolyn disodium & zaprinast effects.Formula:C17H19F2N5O2SPurity:99.11%Color and Shape:SolidMolecular weight:395.43Ref: TM-T21874
1mg40.00€2mg52.00€5mg88.00€10mg126.00€25mg274.00€50mg432.00€100mg638.00€1mL*10mM (DMSO)87.00€Naftopidil
CAS:Naftopidil (KT-611) (INN, marketed under the brand name Flivas), an antihypertensive medicine, is used as a selective α1-adrenergic receptor antagonist or α-Formula:C24H28N2O3Purity:99.60% - 99.97%Color and Shape:White Crystalline PowderMolecular weight:392.49
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