PI3K/Akt/mTOR Signaling
PI3K/Akt/mTOR signaling inhibitors are compounds that target the phosphoinositide 3-kinase (PI3K), Akt kinase, and mammalian target of rapamycin (mTOR) pathways. These pathways are critical regulators of cell growth, survival, metabolism, and autophagy, making them key targets in cancer research and metabolic disorders. Inhibiting these pathways can help to control tumor growth and proliferation, offering potential therapeutic strategies for various cancers and other diseases characterized by dysregulated cell signaling. At CymitQuimica, we offer a comprehensive selection of high-quality PI3K/Akt/mTOR inhibitors to support your research in oncology, cellular signaling, and metabolic diseases.
Subcategories of "PI3K/Akt/mTOR Signaling"
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Products of "PI3K/Akt/mTOR Signaling"
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NSC781406
CAS:NSC781406 is a highly effective inhibitor of PI3K and mTOR (IC50: 2 nM for PI3Kα).Formula:C29H27F2N5O5S2Purity:99.58%Color and Shape:SolidMolecular weight:627.68Ref: TM-T16355
2mg42.00€5mg64.00€10mg93.00€25mg168.00€50mg245.00€100mg375.00€200mg533.00€1mL*10mM (DMSO)88.00€Azerutamig
Azerutamig is a dual-specificity antibody targeting KLRK1/ERBB2 of type (H-γ1_L-κ)_scFvkh-H-γ1(h-CH2-CH3).Color and Shape:Odour LiquidSTL127705
CAS:STL127705 inhibits Ku 70/80 protein & DNA-PKCS kinase, IC50s: 3.5 μM & 2.5 μM.Formula:C22H20FN5O4Purity:97.41% - 99.18%Color and Shape:SolidMolecular weight:437.42Ref: TM-T13017
1mg114.00€5mg274.00€10mg432.00€25mg715.00€50mg1,008.00€100mg1,359.00€500mg2,717.00€1mL*10mM (DMSO)316.00€Mutated EGFR-IN-1
CAS:Mutated EGFR-IN-1 (Osimertinib analog) is a useful intermediate for the inhibitors design for mutated EGFR, such as L858R EGFR, Exonl9 deletion activatingFormula:C25H31N7OPurity:98.91%Color and Shape:SolidMolecular weight:445.56OTSSP167 hydrochloride
CAS:OTSSP167 hydrochloride is a highly potent inhibitor of MELK(IC50 : 0.41 nM).Formula:C25H29Cl3N4O2Purity:99.41%Color and Shape:SolidMolecular weight:523.88Ref: TM-T21559
1mg40.00€2mg52.00€5mg88.00€10mg119.00€25mg188.00€50mg354.00€100mg528.00€1mL*10mM (DMSO)92.00€PI3K-IN-9
CAS:PI3K-IN-9 is a potent and selective inhibitor of PI3Kδ(IC50 of 8.9 nM).Formula:C19H23N7OPurity:98%Color and Shape:SolidMolecular weight:365.43HTH-02-006
HTH-02-006, a NUAK2 inhibitor (IC50 = 126 nM), decreases phosphorylated MYPT1 levels in HuCCT-1 cells and inhibits YAP-driven cell proliferation, hepatomegaly,Formula:C25H29IN6O3Purity:98%Color and Shape:SoildMolecular weight:588.45PD 174265
CAS:PD 174265 is an effective, selective and reversible inhibitor of epidermal growth factor receptor (EGFR) with an IC50 of 0.45 nM.Formula:C17H15BrN4OPurity:98.88%Color and Shape:SolidMolecular weight:371.23Sulforaphene
CAS:Sulforaphene, from radish seeds, aids cancer cell apoptosis and inhibits migration; has an ED50 for velvetleaf at ~2x10^-4 M.Formula:C6H9NOS2Purity:98.01% - 99.19%Color and Shape:Slightly Yellowish LiquidMolecular weight:175.27Ref: TM-TL0016
1mg37.00€2mg52.00€5mg79.00€10mg119.00€25mg227.00€50mg338.00€100mg500.00€1mL*10mM (DMSO)69.00€Losatuxizumab
CAS:Losatuxizumab (ABT-806) is an anti-EGFR monoclonal antibody with potential anti-tumor activity for the study of advanced malignant solid tumors.Purity:95% - 95%Color and Shape:LiquidTenalisib
CAS:Tenalisib (RP6530) (RP6530) is a potent and selective inhibitor of PI3Kδ and PI3Kγ(IC50 values of 25 and 33 nM, respectively.)Formula:C23H18FN5O2Purity:99.71%Color and Shape:SolidMolecular weight:415.42Ref: TM-T13119
1mg38.00€2mg49.00€5mg81.00€10mg111.00€25mg188.00€50mg304.00€100mg457.00€1mL*10mM (DMSO)88.00€YKL-05-099
CAS:YKL-05-099 is a salt-inducible kinase (SIK) inhibitor. It can inhibit the activity of SIK1 and SIK3.Cost-effective and quality-assured.Formula:C32H34ClN7O3Purity:99.57% - 99.66%Color and Shape:SolidMolecular weight:600.11Ref: TM-T17271
1mg74.00€5mg120.00€10mg180.00€25mg311.00€50mg464.00€100mg655.00€1mL*10mM (DMSO)159.00€Nimotuzumab
CAS:Nimotuzumab is a humanized therapeutic monoclonal antibody against epidermal growth factor receptor EGFR).Purity:95.00%Color and Shape:Liquid8-Chloroadenosine
CAS:8-Chloroadenosine (NSC-354258) is a 5' AMP-activated protein kinase agonist potentially for the treatment of chronic lymphocytic leukemia.Formula:C10H12ClN5O4Purity:98.75% - 99.48%Color and Shape:SolidMolecular weight:301.69Ref: TM-T19661
1mg35.00€5mg120.00€10mg188.00€25mg330.00€50mg494.00€100mg702.00€500mg1,406.00€1mL*10mM (DMSO)166.00€Mutated EGFR-IN-2
CAS:Mutated EGFR-IN-2 is an inhibitor of mutant-selective EGFR.Formula:C29H35FN8O3Purity:98%Color and Shape:SolidMolecular weight:562.64Nazartinib
CAS:Nazartinib (EGF816) (EGF816, NVS-816) is a covalent, irreversible, mutant-selective EGFR inhibitor that has nanomolar inhibitory potency against activating mt (Formula:C26H31ClN6O2Purity:98.31% - ≥95%Color and Shape:Solid PowderMolecular weight:495.02Ref: TM-T3506
1mg37.00€5mg79.00€10mg119.00€25mg187.00€50mg354.00€100mg528.00€500mg1,159.00€1mL*10mM (DMSO)87.00€WZ8040
CAS:WZ8040 is a novel mutant-selective irreversible EGFRT790M inhibitor, does not inhibit ERBB2 phosphorylation (T798I).Formula:C24H25ClN6OSPurity:97.42%Color and Shape:SolidMolecular weight:481.01EGFR mutant-IN-1
EGFR mutant-in-1, a 5-methylpyrimidopyridone, selectively inhibits EGFRL858R/T790M/C797S mutants with an IC50 of 27.5 nM, lessening EGFRWT impact.Formula:C34H39ClFN7O2Purity:98%Color and Shape:SolidMolecular weight:632.17BMS-690514
CAS:BMS-690514 is a potent and orally active inhibitor of EGFR and VEGFR. It has IC50s of 5, 20 and 60 nM for EGFR, HER 2 and HER 4, respectively.Formula:C19H24N6O2Purity:99.08%Color and Shape:SolidMolecular weight:368.43Erlotinib
CAS:Erlotinib (NSC-718781) is an EGFR inhibitor (IC50: 2 nM). It is used for the treatment of non-small cell lung cancer.Formula:C22H23N3O4Purity:98.19% - 99.98%Color and Shape:White To Off-White PowderMolecular weight:393.44
