PI3K/Akt/mTOR Signaling
PI3K/Akt/mTOR signaling inhibitors are compounds that target the phosphoinositide 3-kinase (PI3K), Akt kinase, and mammalian target of rapamycin (mTOR) pathways. These pathways are critical regulators of cell growth, survival, metabolism, and autophagy, making them key targets in cancer research and metabolic disorders. Inhibiting these pathways can help to control tumor growth and proliferation, offering potential therapeutic strategies for various cancers and other diseases characterized by dysregulated cell signaling. At CymitQuimica, we offer a comprehensive selection of high-quality PI3K/Akt/mTOR inhibitors to support your research in oncology, cellular signaling, and metabolic diseases.
Subcategories of "PI3K/Akt/mTOR Signaling"
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Products of "PI3K/Akt/mTOR Signaling"
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Butein
CAS:Butein is a cAMP-specific PDE inhibitor, protein tyrosine kinase inhibitor, and SIRT1 activator.Cost-effective and quality-assured.Formula:C15H12O5Purity:100% - 99.85%Color and Shape:SolidMolecular weight:272.25Ref: TM-T6427
1mg43.00€2mg56.00€5mg88.00€10mg106.00€25mg213.00€50mg344.00€100mg550.00€1mL*10mM (DMSO)87.00€Astragaloside VI
CAS:Astragaloside VI could improve wound healing by activating the EGFR/ERK signaling pathway.Formula:C47H78O19Purity:98%Color and Shape:SolidMolecular weight:947.122Genistein
CAS:Genistein (NPI 031L) is a natural soy isoflavone, a multi-targeted tyrosine kinase inhibitor. Genistein has antitumor effects. Cost effective and quality assured.Formula:C15H10O5Purity:98.22% - 99.69%Color and Shape:Rectangular Or Six-Sided Rods From 60% Alcohol Dendritic Needles From Ether SolidMolecular weight:270.24EGFR Protein, Human, Recombinant (His & Avi), Biotinylated
EGFR Protein, Human, Recombinant (His & Avi), Biotinylated is expressed in HEK293 mammalian cells with C-His-Avi tag.Color and Shape:Lyophilized PowderMolecular weight:71.5 kDa (predicted). Due to glycosylation, the protein migrates to 90-120 kDa based on Tris-Bis PAGE result.GSK2292767
CAS:GSK2292767 is a potent and selective PI3Kδ inhibitor.Formula:C24H28N6O5SPurity:98%Color and Shape:SolidMolecular weight:512.58YK-029A
CAS:YK-029A, an orally active EGFR mutant inhibitor, targets both EGFR T790M and EGFRex20ins mutations.Formula:C27H32N8O2Purity:98%Color and Shape:SolidMolecular weight:500.6PD153035
CAS:PD153035 (NSC-669364) hydrochloride is an effective and selective inhibitor of EGFR (Ki/IC50: 5.2/29 pM, in cell-free assays); little inhibitory against FGFR,Formula:C16H14BrN3O2Purity:98.47% - 99.29%Color and Shape:SolidMolecular weight:360.21CAL-130 Racemate
CAS:CAL-130 Racemate is the racemate of CAL-130. CAL-130 is a PI3Kδ and PI3Kγ inhibitor (IC50s: 1.3 and 6.1 nM).Formula:C23H22N8OPurity:98%Color and Shape:SolidMolecular weight:426.47GSK-3β inhibitor 19
GSK-3β Inhibitor 19 (compound 36) is an inhibitor of GSK-3β with an IC50 value of 70 nM. It is applicable in research related to anti-inflammatory and Alzheimer's disease.Formula:C15H12N4O2SColor and Shape:SolidMolecular weight:312.35WAY-270360
CAS:WAY-270360 (N-[4-(1H-benzimidazol-2-yl)phenyl]-2,4-dimethoxybenzamide) is a sirtuin modulator and an epidermal growth factor receptor (EGFR) inhibitor.Formula:C22H19N3O3Purity:98.66%Color and Shape:SolidMolecular weight:373.4Rostafuroxin
CAS:Rostafuroxin (PST 2238) has been used in trials studying the treatment of Essential Hypertension.Formula:C23H34O4Purity:100% - 99.08%Color and Shape:SolidMolecular weight:374.51PI3K-IN-6
CAS:PI3K-IN-6 is an oral active and highly selective inhibitor of phosphoinositide 3-kinase (PI3K) β/δ(IC50 values of 7.8 nM/5.3 nM , respectively).Formula:C17H14Cl2FN9OPurity:98%Color and Shape:SolidMolecular weight:450.26TG100-115
CAS:TG100-115 is a PI3Kγ/δ inhibitor (IC50: 83/235 nM), with fewer effects on PI3Kα/β.Formula:C18H14N6O2Purity:100% - 98.95%Color and Shape:SolidMolecular weight:346.34Ref: TM-T2672
1mg43.00€5mg85.00€10mg115.00€25mg210.00€50mg378.00€100mg588.00€500mg1,216.00€1mL*10mM (DMSO)92.00€Protopine hydrochloride
CAS:Protopine inhibits thromboxane, lowers intracellular calcium, and reduces cell adhesion by altering adhesive factors.Formula:C20H20ClNO5Purity:98%Color and Shape:Prisms From Alc SolidMolecular weight:389.83MARK4 inhibitor 2
MARK4 Inhibitor 2 is a potent inhibitor of Microtubule Affinity-Regulating Kinase 4 (MARK4), exhibiting a Kₘ of 6.3×10⁷ and an IC₅₀ of 0.82 μM.Formula:C34H30N4O3Purity:98%Color and Shape:SolidMolecular weight:542.63EGFR/HER2/DHFR-IN-2
EGFR/HER2/DHFR-IN-2 (Compound 4b) serves as an inhibitor for EGFR, HER2, and DHFR, with IC50 values of 0.248, 0.156, and 0.138 μM, respectively.Purity:98%Color and Shape:Odour SolidErucic acid
CAS:Increased levels of erucic acid (22:1n9) have been found in the red blood cell membranes of autistic subjects with developmental regression (PMID: 16581239 ).Formula:C22H42O2Purity:99.64%Color and Shape:Needles From Alcohol Liquid OthersolidMolecular weight:338.57PI3Kα/mTOR-IN-1
CAS:PI3Kα/mTOR-IN-1 is a potent dual inhibitor of PI3Kα/mTOR.Formula:C16H18N6OPurity:99.3%Color and Shape:SolidMolecular weight:310.35GSK-3β inhibitor 26
CAS:GSK-3β inhibitor26 (Compound D14) is a GSK-3β inhibitor with an IC50 of 18.23 μM. This compound is applicable in research related to cancer, inflammation, and neurodegenerative diseases.Formula:C15H11N3O3Color and Shape:SolidMolecular weight:281.266PI-3065
CAS:PI-3065 is a novel potent and selective PI3K p110δ inhibitor.Formula:C27H31FN6OSPurity:98.39% - ≥95%Color and Shape:SolidMolecular weight:506.64
