Deuterated Compounds

Applications 1,2,4-Trichlorobenzene-d3 (CAS# 2199-72-6) is a useful isotopically labeled research compound.

Applications N,N-Dimethyltetradecylamine-d6 N-Oxide is an isotopic analog of N,N-Dimethyltetradecylamine Oxide (3332-27-2).

Applications p-​Tolunitrile-d7 is an isotopic analog of p-​Tolunitrile (T536235), a reagent used in the preparation of 1H-Indazoles from imidates and nitrosobenzenes. References Wang, Q. et al.: Org. Lett., 18, 2102 (2016);

Applications 4-​(Dimethyloxidoamino)​butanoic Acid-d6 Hydrochloride is the labelled form of 4-​(Dimethyloxidoamino)​butanoic Acid (D447160). 4-​(Dimethyloxidoamino)​butanoic Acid is a metabolite of Lauramine Oxide (L178530), which is a frequently used amine oxide surfactant. It is strongly hydrophilic , and it forms normal micelles and normal liquid crystalline phases. References Kocherbitov, v., et al.: J. Molec. Struct.: Theochem., 808, 111 (2007); Kocherbitov, v., et al.: J. Phys. Chem. B., 110 (27), 13649 (2006); Turan, T.S., et al.: Xenobiotica, 11, 447 (1981)

Applications 4-​(Dimethylamino)​benzoic-​2,​3,​5,​6-​d4 Acid is an intermediate in the synthesis of DMABA-d4 NHS Ester (D678402), which is a labelled DMABA NHS ester (D678400). DMABA NHS ester is a reagent that reacts with the primary amine group of PE lipids. DMABA NHS ester has been used in combination with DMABA NHS ester-d4, -d6, and -d10 to study relative changes in PE lipid abundance before and after radical oxidation. References Wester, H., et al.: Nucl. Med. Bio., 23, 365 (1996), Frees, D., et al.: Mol. Microbiol., 48, 1565 (2003), Michel, A., et al.: J. Bacteriol., 188, 5783 (2006), Voelker, T., et al.: Bioorg. Med. Chem., 17, 2047 (2009),

Vitamin D3-d6 is a vitamin that has ionizable properties. It is available in the form of an oil and can be used as a dietary supplement for infants, as well as adults. Vitamin D3-d6 has been validated by various assays, including those based on chemical ionization, high-performance liquid chromatography, and gas chromatography. Sample preparation procedures include saponification and extraction with isooctane. The analytical method involves detection by UV light at 254 nm or fluorescence at 365 nm. The efficiency of this vitamin is low because it easily degrades when exposed to light or air.

Applications Isotope labelled benzyl bromide is a compound used in organic synthesis for the introduction of the benzyl protecting group for alcohols and carboxylic acids. Not a dangerous good if item is equal to or less than 1g/ml and there is less than 100g/ml in the package References Kudou, N., et al.: Euro. J. Med. Chem., 60, 76 (2013); Cahiez, G., et al.: Advan. Synthesis. Catalysis., 354, 1519 (2012);

Applications (9β,10α)-4-Chloro-Androst-4-ene-3,17-dione-d4 is an isotope labelled impurity of Androstenedione (A637550), a Testosterone (T155000) precursor and metabolite with androgenic activity. References Walker, V.R., et al.: Anal. Biopchem., 234, 194 (1996); King, D.S., et al.: J. Am. Med. Assoc., 281, 2020 (1999)

Applications Labelled Malic Acid. The naturally occuring isomer is the L-form which has been found in apples and many other fruits and plants. Selective α-amino protecting reagent for amino acid derivatives. Versatile synthon for the preparation of chiral compounds including κ-opioid receptor agonists, 1α,25-dihydroxyvitamin D3 analogue, and phoslactomycin B. References Rindi, G., et al.: Biochem. J., 80, 214 (1961), Wolfgang, M., et al.: J. Biol. Chem., 281, 37265 (2006), Navarro, D., et al.: Metab. Brain Dis., 23, 115 (2008),

Please enquire for more information about Potassium thiocyanate-13C including the price, delivery time and more detailed product information at the technical inquiry form on this page

Applications Isotope labelled Triglycidyl isocyanurate is a reagent used in the synthesis of N-Benzyl Metaxalone (B285000), which is a muscle relaxant used to relax muscles and relieve pain. Not a dangerous good if item is equal to or less than 1g/ml and there is less than 100g/ml in the package References Toth, P.E., et al.: Clin. Ther., 26, 1355 (2004)

6,7-Bis-(d3)-methoxy-3,4-dihydroisoquinoline (N-1) is a compound that has been used to study the photophysical properties of molecules. It can be synthesized by demethylation and allylation of 6,7-bis-(d3)-methoxy-3,4-dihydroisoquinoline (N). This compound has two methoxy groups on the benzene ring. The chemical reactions are carried out in the presence of phosphotungstic acid and hydrochloric acid. The structural analysis was done by using halides. 6,7-Bis-(d3)-methoxy-3,4-dihydroisoquinoline (N) is also known as dimethyl fumarate or maleate.

Applications Ethyl Cyanoacetate-d2 is the deuterated form of Ethyl Cyanoacetate (E905555), which is a reagent used in the labeled pyrimidine and purine synthesis;Also, it is an intermediate used in the synthesis of N-(3-Chloro-6,11-dihydro-6-methyl-5,5-dioxidodibenzo[c,f][1,2]thiazepin-11-yl)-β-alanine-d4 (C424342), which is an isotope labeled N-(3-Chloro-6,11-dihydro-6-methyl-5,5-dioxidodibenzo[c,f][1,2]thiazepin-11-yl)-β-alanine is a metabolite of Tianeptine (T436800), a tricyclic compound with psychostimulant, anti-ulcer and anti-emetic properties. Antidepressant. Not a dangerous good if item is equal to or less than 1g/ml and there is less than 100g/ml in the package References Das, S., et al.: J. Med. Chem., 52, 5937 (2009), Kim, K., et al.: Bioorg. Med. Chem. Lett., 19, 5225 (2009); Malen, C., et al.: Experientia, 28, 811 (1972), Safa, A., et al.: J. Biol. Chem., 262, 7884 (1987), Ford, J.M., et al.: Pharmacol. Rev., 42, 155, (1990), Pierre, A., et a.: Cancer Res., 51, 2312 (1991), Nair, M. et al.: Analyst, 123, 2267 (1998)

Applications Dimethyl chlorothiophosphate-D6 is a labelled analog of Dimethyl chlorothiophosphate (D473292). Dimethyl chlorothiophosphate is an organophosphorus reagent that is used to synthesize phosphorus analogues of γ-aminobutyric acid, compounds that exhibit anticonvulsant properties. Dimethyl chlorothiophosphate is also used as a reagent to synthesize Parathion (P192220), a widely used pesticide. Not a dangerous good if item is equal to or less than 1g/ml and there is less than 100g/ml in the package References Cates, L., et al.: J. Med. Chem., 27, 654 (1984); DeBruin, K. & Boros, E.: J. Org. Chem., 55, 609 (1990); Hall, S.: J. Am. Chem. Soci., 72, 2768 (1950); Kotronarou, A. & Hoffmann, M.: Env. Sci. Tech., 26, 1460 (1992)