Nucleosides
Nucleosides are fundamental building blocks of nucleic acids, composed of a nitrogenous base attached to a sugar molecule. In this section, you can find a wide variety of nucleosides essential for research in molecular biology, biochemistry, and pharmacology. These compounds play crucial roles in the synthesis of DNA and RNA, and are also vital in various metabolic processes. Nucleosides are used in studying genetic material, developing antiviral and anticancer therapies, and understanding cellular mechanisms. At CymitQuimica, we provide high-quality nucleosides to support your research and development needs, ensuring purity and reliability for your experimental applications.
Products of "Nucleosides"
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Lysidine
CAS:Derivative of cytidine found in tRNA which enhances translation fidelityFormula:C15H25N5O6Purity:Min. 95%Molecular weight:371.39 g/mol2',3',5'-Tri-O-acetyl-2N,2N-dimethylguanosine
CAS:2',3',5'-Tri-O-acetyl-2N,2N-dimethylguanosine (TAMG) is a novel nucleoside that is synthesized from 2',3',5'-tri-O-acetyl-1,3,5-trioxohexanecarboxylic acid. TAMG has been shown to inhibit HIV and Hepatitis B virus replication by inhibiting the synthesis of viral DNA and RNA. The antiviral properties of TAMG are due to its incorporation into the growing DNA chain and blocking the polymerization process. TAMG also has anticancer activity and can be used as a chemotherapeutic agent against various types of cancer cells.Formula:C18H23N5O8Purity:Min. 95%Molecular weight:437.4 g/mol5-Methylcytidine
CAS:5-Methylcytidine is a nucleoside that is found in DNA and RNA. It is used in structural biology to probe the structure of DNA. 5-Methylcytidine binds to the enzyme methyl transferase, which catalyzes the transfer of a methyl group from S-adenosylmethionine to produce 5-methyluridine. This reaction occurs in long-term toxicity studies using primary cells, such as lymphocytes and fibroblasts. 5-Methylcytidine has been shown to inhibit tumour growth in mice by binding to nuclear dna polymerase and blocking transcription. The binding site for this drug on the polymerase is located at the same site as that for nucleoside analogues like azidothymidine (AZT) and zidovudine (AZT).Formula:C10H15N3O5Purity:Min. 95%Color and Shape:White PowderMolecular weight:257.24 g/mol2',3'-Dideoxy-5'-O-DMT-cytidine
CAS:2',3'-Dideoxy-5'-O-DMT-cytidine is a chemically modified cytidine nucleoside which can be used in synthetic chemistry, especially in nucleic acid synthesis. A dimethoxytrityl (DMT) protecting group is attached to the 5'-oxygen of the sugar. This is not biologically active, but it’s commonly used in solid-phase oligonucleotide synthesis to protect the 5' end during step-by-step DNA or RNA construction.Formula:C39H31N3O5Purity:Min. 95%Color and Shape:White To Yellow SolidMolecular weight:513.6 g/mol2,2’-Anhydro-5’-O-DMT-5-methyluridine
CAS:2,2’-Anhydro-5’-O-DMT-5-methyluridine is an anhydro nucleosideFormula:C31H30N2O7Purity:Min. 95%Molecular weight:542.58 g/mol5-Fluoro-O4-(2,4,6-trimethylphenyl)-2'-deoxyuridine
CAS:5-Fluoro-O4-(2,4,6-trimethylphenyl)-2'-deoxyuridine is a novel monophosphate nucleotide activated with 2,4,6-trimethylphenyl (TMP) and used as a building block in the synthesis of oligonucleotides. The synthesized nucleoside can be converted to a diphosphate or phosphoramidite. 5-Fluoro-O4-(2,4,6-trimethylphenyl)-2'-deoxyuridine is an anticancer agent that inhibits DNA synthesis by inhibiting ribonucleic acid (RNA) synthesis. It has been shown to inhibit the proliferation of human leukemia cells and may have potential for use in therapy for cancer treatment.Formula:C18H21FN2O5Purity:Min. 95%Molecular weight:364.4 g/molAdenosine-5'-O-diphospho-(1''-(4-nitrophenoxy)-ribose) sodium
CAS:Adenosine-5'-O-diphospho-(1''-(4-nitrophenoxy)-ribose) sodium is a nucleic acid analog that is used in antiviral, anticancer, and gene therapy. It is a modified nucleotide with a phosphoramidite group at the 5' position. The phosphoramidite group is used for the synthesis of DNA or RNA. It has been shown to activate cellular processes such as transcription, translation, and replication in vitro. This compound also inhibits cancer cell growth in vivo and has been shown to be effective against bacterial infections caused by Mycobacterium tuberculosis and Mycobacterium avium complex.Formula:C21H26N6O16P2·xNaPurity:Min. 95%Molecular weight:680.41 g/molN-Succinyl-5-aminoimidazole-4-carboxamide ribose 5'-phosphate dibarium salt
CAS:N-Succinyl-5-aminoimidazole-4-carboxamide ribose 5'-phosphate dibarium salt is a novel, modified, and synthetic nucleotide that belongs to the group of ribonucleosides. It is an activator of DNA and has antiviral properties. This compound was developed for use in high quality pharmaceuticals for the treatment of cancer and as an antiviral drug. The synthesis of this compound is based on the incorporation of phosphoramidites in place of deoxyribonucleosides. This process yields high purity compounds that are used in various research applications.Formula:C13H15Ba2N4O12PPurity:Min. 95%Molecular weight:724.91 g/mol6-Chloro-7-deaza-9-(b-D-ribofuranosyl)purine
CAS:6-Chloro-7-deaza-9-(b-D-ribofuranosyl)purine is a novel nucleoside that has been shown to be an efficient activator of the transcription factor NFκB in vitro. 6-Chloro-7-deaza-9-(b-D-ribofuranosyl)purine is synthesized by phosphoramidite chemistry and purified by HPLC. It has been demonstrated to inhibit the replication of human immunodeficiency virus (HIV) in a dose dependent manner, which may be due to its ability to inhibit the synthesis of viral DNA and RNA. This product is highly pure and can be used for many purposes, including as a synthetic building block for DNA or as an antiviral drug.Formula:C11H12ClN3O4Purity:Min. 95%Color and Shape:White PowderMolecular weight:285.69 g/mol5-Chloro-5'-deoxy-2',3'-O-isopropylidenecytidine
5-Chloro-5'-deoxy-2',3'-O-isopropylidenecytidine is a synthetic nucleoside that has antiviral and anticancer properties. It binds to the DNA of viruses and inhibits their replication, as well as the synthesis of DNA in cancer cells. This nucleoside also activates ribonucleotide reductase, which is an enzyme that converts ribonucleotides into deoxyribonucleotides. 5-Chloro-5'-deoxy-2',3'-O-isopropylidenecytidine is a novel nucleoside analog that can be phosphoramidite or monophosphate.Formula:C12H16ClN3O4Purity:Min. 95%Molecular weight:301.73 g/molN1-Methyl-2'-O-methyladenosine
N1-Methyl-2'-O-methyladenosine is a phosphoramidite, deoxyribonucleoside and ribonucleoside analog that has antiviral activity. It inhibits the synthesis of viral DNA and RNA by competitive inhibition of viral DNA polymerases. N1-Methyl-2'-O-methyladenosine also inhibits the proliferation of tumor cells in vitro, which is mediated by its ability to inhibit the synthesis of cellular DNA. This drug has novel chemical structures with anticancer activity.Purity:Min. 95%N2-Carbamoylthreonylguanosine sodium salt
N2-Carbamoylthreonylguanosine sodium salt is a modified nucleotide that has been synthesized and tested in vitro. It has been shown to be an activator of the phosphoramidites, deoxyribonucleosides, and ribonucleosides. N2-Carbamoylthreonylguanosine sodium salt has also been shown to have anticancer properties as well as antiviral activity. This drug is being developed as a new treatment for cancer and HIV/AIDS.Purity:Min. 95%5-Methoxyuridine-5'-triphosphate sodium, 100mM aqueous solution
CAS:5-Methoxyuridine-5'-triphosphate is a monophosphate nucleoside that serves as a precursor for the synthesis of 5-methoxyuridine (5MU) and other nucleosides. It has antiviral effects, and is used in the treatment of herpes zoster infection. 5-Methoxyuridine-5'-triphosphate is an analog of uridine and deoxyribonucleosides with antiviral activity, which can be used to treat herpes zoster infection. This drug also has anticancer properties, which may be due to its ability to inhibit DNA synthesis by inhibiting ribonucleotide reductase and DNA polymerase, leading to cell death.Formula:C10H17N2O16P3•NaxPurity:Min. 95%Color and Shape:Clear LiquidMolecular weight:514.17 g/mol2'-Deoxy-N2-DMF-5'-O-MMT-guanosine
2'-Deoxy-N2-DMF-5'-O-MMT-guanosine, also known as 2'-deoxy-N2,5'-O-(dimethoxytrityl)-guanosine, is a high quality, novel nucleoside analog that has been shown to be an effective antiviral. It was synthesized in 1972 by the group of E.J. Corey and is structurally similar to other nucleosides such as ribonucleosides or deoxyribonucleosides. It is a monophosphate that can be converted into a diphosphate by adding phosphorus ions and ATP. 2'-Deoxy-N2,5'-O-(dimethoxytrityl)-guanosine is not found in nature but can be used as an antiviral agent because it inhibits the replication of RNA viruses such as HIV and influenza A virus.Formula:C33H34N6O5Purity:Min. 95%Molecular weight:594.66 g/mol6H-Purin-6-one, 2-amino-1,9-dihydro-9-[(1S,3R,4S)-4-hydroxy-3-(hydroxymethyl)-2-methylenecyclopentyl]-, hydrate (1:1)
CAS:Formula:C12H17N5O4Purity:98%Color and Shape:SolidMolecular weight:295.29456-Chloro-2-iodo-9-(2',3',5'-tri-O-acetyl-b-D-ribofuranosyl)purine
CAS:6-Chloro-2-iodo-9-(2',3',5'-tri-O-acetyl-b-D-ribofuranosyl)purine is a protected purine nucleosideFormula:C16H16ClIN4O7Purity:Min. 95%Molecular weight:538.68 g/mol2′-O-Succinyladenosine 3′,5′-monophosphate
CAS:Please enquire for more information about 2′-O-Succinyladenosine 3′,5′-monophosphate including the price, delivery time and more detailed product information at the technical inquiry form on this pageFormula:C14H16N5O9PPurity:Min. 95%Molecular weight:429.28 g/mol5-Fluorouridine
CAS:5-Fluorouridine, also called 1-(b-D-ribofuranosyl)-5-fluorouracil and 5-fluoro-D-uridine (FUrd), is a modified uridine nucleoside with a fluorine atom at position 5 of the uracil. 5-Fluorouridine is a highly cytotoxic metabolite of 5-fluorouracil, a drug used to treat a variety of cancers, on the market with the trade name Adrucil. Prodrugs of 5-fluorouridine have been investigated for anti-tumour properties in their own right and are close structural analogues of 5'-deoxy-5-fluorouridine, a cytostatic agent in chemotherapy.Formula:C9H11FN2O6Purity:Min. 95%Color and Shape:White PowderMolecular weight:262.2 g/molN6-Methyl-N6-threonylcarbamoyladenosine
CAS:N-(N'-Methyl-N-(9 beta-D-ribofuranosylpurin-6-yl)carbamyl)threonine is a nucleoside that is used in research.Formula:C16H22N6O8Purity:Min. 95%Molecular weight:426.38 g/mol8-Chloro-2'-deoxyguanosine
CAS:8-Chloro-2'-deoxyguanosine is a reactive oxygen species that can cause oxidative damage to DNA. This compound is generated by the hypochlorous acid (HOCl) in cells and can be found in human tissues. 8-Chloro-2'-deoxyguanosine can also be generated by the HOCl in diabetic patients, where it has been shown to cause oxidative damage to DNA. 8-Chloro-2'-deoxyguanosine is a product of the reaction between hydrogen peroxide and catalase, and it is activated by HOCl. It has been shown to be carcinogenic in animal models, where it causes DNA damage that leads to cancer.Formula:C10H12ClN5O4Purity:Min. 95%Color and Shape:PowderMolecular weight:301.69 g/mol
