TNF
Los inhibidores del factor de necrosis tumoral (TNF) son compuestos que bloquean la actividad del TNF, una citocina involucrada en la inflamación y la regulación de la apoptosis. El TNF puede inducir apoptosis en algunos tipos celulares mientras promueve la supervivencia y la inflamación en otros. Inhibir el TNF es crucial en el tratamiento de enfermedades autoinmunes, condiciones inflamatorias crónicas y ciertos tipos de cáncer. Los inhibidores de TNF ayudan a modular la respuesta inmunitaria y a reducir el daño tisular causado por la inflamación excesiva. En CymitQuimica, ofrecemos una amplia gama de inhibidores de TNF de alta calidad para apoyar su investigación en inmunología, inflamación y apoptosis.
Productos de "TNF"
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Dacetuzumab
CAS:Dacetuzumab (SGN 40) is a humanized anti-CD40 monoclonal antibody with antitumor activity for the study of recurrent diffuse large B-cell lymphoma.Pureza:95% - 95%Forma y color:LiquidMitazalimab
CAS:Mitazalimab (ADC-1013/JNJ-64457107) is a CD40 agonist that stimulates T cells to attack tumors and remodels the tumor microenvironment.Pureza:95% - 95%Forma y color:LiquidGNE684
CAS:GNE684 inhibits RIP1; Ki app: 21 nM (human), 189 nM (mouse), 691 nM (rat).Fórmula:C23H24N6O3Pureza:98%Forma y color:SolidPeso molecular:432.48Ragifilimab
CAS:Ragifilimab (INCAGN-1876), a GITR-targeting agonist antibody, may treat advanced solid tumors.Pureza:SDS-PAGE:95% SEC-HPLC:99.99%Forma y color:LiquidPeso molecular:146.46 kDaPK68
CAS:PK68 selectively inhibits RIPK1 (IC50=90nM), potentially useful in inflammation and cancer metastasis studies.Fórmula:C22H24N4O3SPureza:98.09% - 98.13%Forma y color:SolidPeso molecular:424.52Ref: TM-T12493
1mg86,00€5mg170,00€10mg274,00€25mg520,00€50mg750,00€100mg1.026,00€200mg1.388,00€1mL*10mM (DMSO)188,00€CPI1189
CAS:CPI1189 (REN-1189) is a TNF-a release inhibitor potentially for the treatment of sciatica and postherpetic neuralgia.Fórmula:C13H18N2O2Pureza:98.87% - 99.68%Forma y color:SolidPeso molecular:234.291-(4-chloro-3-(trifluoromethyl)phenyl)-3-(7-(1-methyl-1H-pyrazol-4-yl)-2,3,4,9-tetrahydro-1H-carbazol-3-yl)urea
CAS:1-(4-chloro-3-(trifluoromethyl)phenyl)-3-(7-(1-methyl-1H-pyrazol-4-yl)-2,3,4,9-tetrahydro-1H-carbazol-3-yl)urea 是一种能够激动 TNF-α的化合物,可以诱导细胞分泌 TNF-α。Fórmula:C24H21ClF3N5OPureza:97.90% - 98.61%Forma y color:SoildPeso molecular:487.9Sotigalimab
CAS:Sotigalimab (APX 005) is a monoclonal antibody targeting CD40 with anticancer activity for the study of metastatic pancreatic cancer.Pureza:95% - 95%Forma y color:LiquidEnavatuzumab
CAS:Enavatuzumab (PDL192) is a humanized monoclonal antibody targeting TWEAK receptor with anti-tumor activity.Pureza:>95%Forma y color:LiquidInfliximab
CAS:Infliximab is a chimeric monoclonal antibody that inhibits TNF-α. Infliximab can be used to treat Crohn's disease and rheumatoid arthritis. Cost-effective and quality-assured.Pureza:98% - 99.70%Forma y color:LiquidPeso molecular:149 kDaTNF α Protein, Human, Recombinant (aa 57-233, His)
TNF alpha Protein, Human, Recombinant (aa 57-233, His) is expressed in E.Forma y color:Lyophilized PowderPeso molecular:18 KDa (reducing condition)Roquinimex
CAS:Roquinimex (FCF89) (Linomide) is a quinoline derivative immunostimulant which increases NK cell activity and macrophage cytotoxicity; inhibits angiogenesis andFórmula:C18H16N2O3Pureza:97.69%Forma y color:SolidPeso molecular:308.33Ref: TM-T4412
2mg44,00€5mg65,00€10mg96,00€25mg167,00€50mg283,00€100mg454,00€200mg648,00€1mL*10mM (DMSO)72,00€TNF-α-IN-1
CAS:TNF-α-IN-1 is a TNF-α inhibitor.Fórmula:C16H14ClN3O5Pureza:98%Forma y color:SolidPeso molecular:363.75Resatorvid
CAS:Resatorvid (TAK-242) inhibits TLR4, with IC50s for IL-6, TNF-R, NO at 1.3, 1.9, 1.8 nM respectively.Fórmula:C15H17ClFNO4SPureza:100% - 99.9%Forma y color:SolidPeso molecular:361.82Ref: TM-TQ0181
1mg49,00€2mg70,00€5mg96,00€10mg164,00€25mg306,00€50mg502,00€100mg805,00€1mL*10mM (DMSO)116,00€L6H21
CAS:L6H21 is an MD-2 inhibitor that can be used to study cognitive impairment and brain damage.Fórmula:C18H18O4Pureza:99.26%Forma y color:SolidPeso molecular:298.33VU0285655-1
CAS:VU0285655-1, a PLD2 inhibitor, halts PLD2-deficient cell growth and protects against high glucose-induced cell death. Used in diabetic retinopathy research.Fórmula:C25H27N5O2Pureza:99.73%Forma y color:SolidPeso molecular:429.51TNF α Protein, Ferret, Recombinant (His)
TNF alpha Protein, Ferret, Recombinant (His) is expressed in E.Forma y color:Lyophilized PowderPeso molecular:18.88 kDa (predicted) same as Tris-Bis PAGE result.TNF α Protein, Human, Recombinant (aa 77-233, His)
TNF alpha Protein, Human, Recombinant (aa 77-233, His) is expressed in E.Pureza:Greater than 95% as determined by reducing SDS-PAGE - SDS-PAGE: 99.66%; SEC-HPLC: 96.3%Forma y color:Lyophilized PowderPeso molecular:16 KDa (reducing condition)Hernandezine
CAS:Hernandezine is an activator of AMPK activator and a selective reversing agent for ABCB1-mediated MDR in cancer cells.Fórmula:C39H44N2O7Pureza:99.53%Forma y color:SolidPeso molecular:652.78Kdo2-Lipid A ammonium
CAS:Kdo2-Lipid A ammonium (KLA) is a selective and potent TLR4 agonist, a lipopolysaccharide.Kdo2-Lipid A ammonium induces the release of TNF and PGE2.Fórmula:C110H214N6O39P2Pureza:98%Forma y color:SolidPeso molecular:2306.84
