TNF
Los inhibidores del factor de necrosis tumoral (TNF) son compuestos que bloquean la actividad del TNF, una citocina involucrada en la inflamación y la regulación de la apoptosis. El TNF puede inducir apoptosis en algunos tipos celulares mientras promueve la supervivencia y la inflamación en otros. Inhibir el TNF es crucial en el tratamiento de enfermedades autoinmunes, condiciones inflamatorias crónicas y ciertos tipos de cáncer. Los inhibidores de TNF ayudan a modular la respuesta inmunitaria y a reducir el daño tisular causado por la inflamación excesiva. En CymitQuimica, ofrecemos una amplia gama de inhibidores de TNF de alta calidad para apoyar su investigación en inmunología, inflamación y apoptosis.
Productos de "TNF"
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Conatumumab
CAS:Conatumumab (AMG 655) targets DR5 to induce apoptosis in tumors, with Kd of 1 nM (long DR5) and 0.8 nM (short DR5).Pureza:> 95% - > 95%Forma y color:LiquidPeso molecular:145 kDa (average)Linarin
CAS:Linarin inhibits acetylcholinesterase, reduces liver injury via TNF-α, protects neurons via PI3K/Akt, and has enhanced absorption with piperine.Fórmula:C28H32O14Pureza:97.95% - 98.99%Forma y color:White To Off White PowderPeso molecular:592.557,3',4'-Tri-O-methylluteolin
CAS:7,3',4'-Tri-O-methylluteolin is anti-inflammatory, antibacterial, antifungal, and has moderate antitrypanosomal effects (MIC 19.0 ug/ml).Fórmula:C18H16O6Pureza:98.66% - 98.99%Forma y color:SolidPeso molecular:328.32Ref: TM-TN1291
1mg87,00€5mg170,00€10mg264,00€25mg452,00€50mg647,00€100mg900,00€1mL*10mM (DMSO)187,00€Ozoralizumab
CAS:Ozoralizumab (ATN-103) is a humanized anti-TNFα antibody and a novel TNFα inhibitor.Pureza:SDS-PAGE:> 95%;SEC-HPLC:95.6%Forma y color:LiquidPeso molecular:38.44 kDaSTING-IN-2
CAS:STING-IN-2 (C-170) is a potent and covalent inhibitor of STING. STING-IN-2 can be used for autoinflammatory disease research.Fórmula:C15H16N2O4Pureza:98.61%Forma y color:SolidPeso molecular:288.3TNF α Protein, Human, Recombinant (His & Avi)
TNF alpha Protein, Human, Recombinant (His & Avi) is expressed in HEK293 mammalian cells with C-His-Avi tag.Forma y color:Lyophilized PowderPeso molecular:20.3 kDa (predicted). Due to glycosylation, the protein migrates to 21-25 kDa based on Tris-Bis PAGE result.(Rac)-Benpyrine
CAS:(Rac)-Benpyrine is a potent and orally active inhibitor of TNF-α.Fórmula:C16H16N6OPureza:98.44%Forma y color:SolidPeso molecular:308.34Ref: TM-T8692
1mg73,00€5mg124,00€10mg187,00€25mg376,00€50mg562,00€100mg802,00€500mg1.644,00€1mL*10mM (DMSO)137,00€Clematichinenoside AR
CAS:Clematichinenoside AR is anti-inflammatory, immunosuppressive, and combats arthritis via PI3K/Akt and TNF-α pathways.Fórmula:C82H134O43Pureza:99.49% - 99.69%Forma y color:SolidPeso molecular:1807.92GSK2593074A
CAS:GSK2593074A (GSK'074) is a programmed necrosis inhibitor that displays inhibitory effects on RIP1 and RIP3.Fórmula:C27H23N5OSPureza:100%Forma y color:SolidPeso molecular:465.57Ref: TM-T11484
1mg114,00€5mg274,00€10mg432,00€25mg725,00€50mg1.017,00€100mg1.359,00€1mL*10mM (DMSO)303,00€Selicrelumab
CAS:Selicrelumab (RG-7876) is an antibody targeting CD40 with potential anti-tumor activity for the study of pancreatic cancer.Pureza:95% - 95%Forma y color:LiquidAdalimumab
CAS:Adalimumab (anti-TNF-alpha) is the first fully human recombinant IgG1 monoclonal antibody that specifically targets human TNF-alpha.Pureza:95% - 99.50%Forma y color:LiquidPeso molecular:145.4 kDaNodinitib-1
CAS:Nodinitib-1 (CID-1088438) is a potent and selective NOD1 inhibitor with an IC50 of 0.56 μM.Fórmula:C14H13N3O2SPureza:99.97% - 99.98%Forma y color:SolidPeso molecular:287.34TNF-α-IN-9
CAS:TNF-α-IN-9 is an NDM-1 inhibitor-3 analog and is a TNF-α inhibitor.TNF-α-IN-9 shows low inhibitory activity.Fórmula:C17H14O4Pureza:98.28%Forma y color:SoildPeso molecular:282.29Teneliximab
CAS:Teneliximab (BMS 224819) is a chimeric monoclonal antibody that blocks CD40-CD40L interactions.Cost-effective and quality-assured.Pureza:95.00% - 99.19% (SEC-HPLC)Forma y color:LiquidPeso molecular:146.06 kDaAstilbin
CAS:Astilbin (Neoastilbin) is actions Flavonoid phytochemical found in St. John′s wort and Traditional Chinese Medicine herbal preparations.Fórmula:C21H22O11Pureza:97% - 99.76%Forma y color:White PowderPeso molecular:450.39Ref: TM-T2794
5mg52,00€10mg77,00€25mg140,00€50mg224,00€100mg334,00€200mg477,00€500mg778,00€1mL*10mM (DMSO)51,00€Sinensetin
CAS:Sinensetin, a citrus flavone, has antiangiogenic, anti-inflammatory properties, and promotes fat formation and breakdown.Fórmula:C20H20O7Pureza:97.74% - 99.33%Forma y color:Pale Creamy Yellow PowderPeso molecular:372.37Zigakibart
CAS:Zigakibart (BION-1301) is a humanized monoclonal antibody targeting TNFSF13 with anti-inflammatory activity for the study of immunoglobulin A nephropathy (IgAN)Forma y color:LiquidSciadopitysin
CAS:Sciadopitysin may thwart diabetic bone disease, boost mitochondria, protect osteoblasts, and hinder Aβ aggregation/neurotoxicity.Fórmula:C33H24O10Pureza:98.14% - 99.17%Forma y color:SolidPeso molecular:580.54Ref: TM-T5S2129
1mg52,00€5mg95,00€10mg162,00€25mg304,00€50mg455,00€100mg653,00€500mg1.349,00€1mL*10mM (DMSO)130,00€UTL-5g
CAS:UTL-5g is a chemoprotective TNF-α inhibitor reducing cisplatin side effects and toxicity in liver, kidneys, and blood.Fórmula:C11H8Cl2N2O2Pureza:99.83%Forma y color:SolidPeso molecular:271.1Ref: TM-T8845
1mg50,00€5mg105,00€10mg164,00€25mg321,00€50mg452,00€100mg645,00€200mg868,00€1mL*10mM (DMSO)129,00€CDC801
CAS:CDC801 is an inhibitor of PDE4 and TNF-α with IC50s of 1.1 μM and 2.5 μM, respectively.Fórmula:C23H24N2O5Pureza:98.81%Forma y color:SolidPeso molecular:408.45
