TNF
Los inhibidores del factor de necrosis tumoral (TNF) son compuestos que bloquean la actividad del TNF, una citocina involucrada en la inflamación y la regulación de la apoptosis. El TNF puede inducir apoptosis en algunos tipos celulares mientras promueve la supervivencia y la inflamación en otros. Inhibir el TNF es crucial en el tratamiento de enfermedades autoinmunes, condiciones inflamatorias crónicas y ciertos tipos de cáncer. Los inhibidores de TNF ayudan a modular la respuesta inmunitaria y a reducir el daño tisular causado por la inflamación excesiva. En CymitQuimica, ofrecemos una amplia gama de inhibidores de TNF de alta calidad para apoyar su investigación en inmunología, inflamación y apoptosis.
Productos de "TNF"
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Lucatumumab
CAS:Lucatumumab (HCD122) is a fully human anti-CD40 monoclonal antibody with anti-tumor activity for the study of multiple myeloma.Pureza:95% - 95%Forma y color:LiquidTNF α Protein, Cynomolgus, Recombinant (His)
TNF alpha Protein, Cynomolgus, Recombinant (His) is expressed in HEK293 mammalian cells with N-His tag.Forma y color:Lyophilized PowderPeso molecular:18.35 kDa (predicted). Due to glycosylation, the protein migrates to 19-25 kDa based on Tris-Bis PAGE result.Utomilumab
CAS:Utomilumab, a humanized IgG2 against T-cell receptor 4-1BB/CD137, shows antitumor effects in advanced cancers.Fórmula:C17H24N8O3Pureza:SDS-PAGE:95.2%;SEC-HPLC:98.5%Forma y color:LiquidPeso molecular:142.77 kDacRIPGBM
CAS:cRIPGBM induces apoptosis in GBM CSCs by targeting RIPK2, with an EC50 of 68 nM in GBM-1 cells.Fórmula:C26H20FN2O2Pureza:98%Forma y color:SolidPeso molecular:411.45Homovanillyl alcohol
CAS:Homovanillyl alcohol is a biological metabolite of Hydroxytyrosol.Fórmula:C9H12O3Pureza:99.62%Forma y color:Cream To Light Brown ChunksPeso molecular:168.19Brentuximab
CAS:Brentuximab is a chimeric antibody targeting CD30 and is a naked antibody to Brentuximab vedotin.Brentuximab has antitumor activity and may be used to studyPureza:95% - 97.1% (SEC-HPLC)Forma y color:LiquidPeso molecular:145.21 kDaGiloralimab
CAS:Giloralimab (ABBV-927) is a antibody targeting CD40 with anticancer activity for the study of triple-negative breast cancer and non-small cell lung cancer.Pureza:95% - 95%Forma y color:LiquidTigatuzumab
CAS:Tigatuzumab (CS-1008) is a humanized monoclonal antibody targeting DR5 and is a TRAIL-R2 agonist with antitumor activity that induces apoptosis in cancer cells.Pureza:95% - 95%Forma y color:LiquidPeso molecular:144.6 (kDa)HOMOPLANTAGININ
CAS:Homoplantaginin is a flavonoid from a traditional Chinese medicine Salvia plebeia,it has a protective and therapeutic effect on hepatocyte injury and showsFórmula:C22H22O11Pureza:97.63% - 99.66%Forma y color:SolidPeso molecular:462.4Ref: TM-T4S0217
5mg50,00€10mg74,00€25mg140,00€50mg226,00€100mg324,00€200mg464,00€1mL*10mM (DMSO)52,00€IA-14069
CAS:IA-14069 is a TNF-a inhibitor with anti-inflammatory activity and pro-inflammatory cytokine production, and is used in the study of colon cancer.Fórmula:C20H15ClF2O4Forma y color:SoildPeso molecular:392.78R-7050
CAS:R-7050 (TNF-α Antagonist III), a tumor necrosis factor receptor (TNFR) antagonist, exhibits heightened selectivity for TNFα.Fórmula:C16H8ClF3N4SPureza:98.64%Forma y color:SolidPeso molecular:380.77Ref: TM-T4637
2mg46,00€5mg66,00€10mg96,00€25mg207,00€50mg283,00€100mg464,00€500mg1.008,00€1mL*10mM (DMSO)74,00€Cot inhibitor-1 hydrochloride
Cot inhibitor-1 hydrochloride blocks TPL-2 kinase (IC50=28nM) and TNF-α synthesis (IC50=5.7nM) in human blood.Fórmula:C27H28Cl3FN8Pureza:98.26%Forma y color:SoildPeso molecular:589.92Ref: TM-T10865L
1mg125,00€5mg240,00€10mg379,00€25mg632,00€50mg899,00€100mg1.216,00€1mL*10mM (DMSO)283,00€Drozitumab
CAS:Drozitumab (PRO 95780) is a fully humanized antibody targeting the death receptor DR5 for the study of triple-negative breast cancer.Pureza:95% - 95%Forma y color:LiquidPeso molecular:143.1 (kDa)Iscalimab
CAS:Iscalimab (CFZ-533) is a humanized monoclonal antibody targeting CD40, used in research on myasthenia gravis and Sjögren’s syndrome.Pureza:>95%Forma y color:LiquidTNF α Protein, Rabbit, Recombinant
Tumor necrosis factor alpha (TNFα) is the prototypic ligand of the TNF superfamily.Pureza:98% - > 99.9%Forma y color:Lyophilized PowderPeso molecular:18 KDa (reducing condition)Prim-O-glucosylcimifugin
CAS:Prim-O-glucosylcimifugin (Cimifugin 7-glucoside) can inhibit the proliferation of SMC stimulated by TNF-alpha, increase the proportion of G0/G1 phase.Fórmula:C22H28O11Pureza:98.57% - 99.92%Forma y color:SolidPeso molecular:468.45Cetrelimab
CAS:Cetrelimab (JNJ 63723283) is a humanized monoclonal antibody targeting PD-1, useful in research on multiple myeloma and bladder cancer.Pureza:>95%Forma y color:LiquidTulisokibart
CAS:Tulisokibart (PRA023) is a humanized anti-TNFSF15 monoclonal antibody used to study colon cancer.Forma y color:LiquidAnti-Mouse TNF α Antibody (TN3-19.12)
Anti-Mouse TNF alpha Antibody is a rat-derived IgG inhibitor targeting mouse TNF alpha.Pureza:95% - ＞10mg/mlForma y color:Odour LiquidGolimumab
CAS:Golimumab (CNTO-148), an anti-TNFα IgG1κ monoclonal antibody with anti-inflammatory and anti-cancer activity, can be used to prevent inflammation and cartilage.Forma y color:LiquidPeso molecular:146.93 kDa
