p53
Los inhibidores de p53 se dirigen a la proteína p53, un supresor tumoral que desempeña un papel crucial en la regulación del ciclo celular, la reparación del ADN y la apoptosis. Aunque p53 a menudo está mutado o inactivado en células cancerosas, su inhibición a veces es necesaria para proteger a las células sanas de la apoptosis durante ciertos tratamientos. Por otro lado, restaurar la función de p53 en los tumores puede conducir a la apoptosis de las células cancerosas. La investigación sobre inhibidores de p53 es compleja y significativa tanto para comprender los mecanismos del cáncer como para desarrollar nuevas terapias. En CymitQuimica, ofrecemos una selección de inhibidores y moduladores de p53 de alta calidad para apoyar su investigación en biología del cáncer, apoptosis y desarrollo terapéutico.
Productos de "p53"
Ordenar por
UNC0646
CAS:UNC0646 is a potent and selective inhibitor of the homologous protein lysine methyltransferases, G9a and GLP with low cellular toxicity.Fórmula:C36H59N7O2Pureza:100%Forma y color:SolidPeso molecular:621.9UNC 0631
CAS:UNC 0631 is a effectvie histone methyltransferase G9a inhibitor (IC50=4 nM).Fórmula:C37H61N7O2Pureza:98.76%Forma y color:SolidPeso molecular:635.93NSC-87877 disodium
CAS:NSC-87877 disodium (NSC87877) is a cell-permeable inhibitor of both SHP-1 and SHP-2. NSC-87877 also inhibits EGF-induced Erk1/2 activation in HEK293 cells.Fórmula:C19H13N3O7S2·2NaPureza:97.89%Forma y color:SolidPeso molecular:503.42HLA-A*02:01&B2M&P53 R175H (HMTEVVRHC) Tetramer Protein, Human, MHC (His & Avi)
p53 is a tumor suppressor protein.Forma y color:Odour Lyophilized PowderAmifostine trihydrate
CAS:Amifostine trihydrate (WR2721) is the first approved radioprotective drug, used to decrease the risk of kidney problems caused by treatment with cisplatin.Fórmula:C5H15N2O3PS·3H2OPureza:99.71% - 99.80%Forma y color:SolidPeso molecular:268.27Anti-p53 Antibody (9D896)
Anti-p53 Antibody (9D896) is an antibody targeting p53. Anti-p53 Antibody (9D896) can be used in ELISA, WB, IHC, IF.Forma y color:Odour LiquidDPBQ
CAS:DPBQ (ZINC1620467) is a p53 activator.Fórmula:C24H14N2O2Pureza:98.73%Forma y color:SolidPeso molecular:362.38Ref: TM-T11092
1mg105,00€2mg158,00€5mg259,00€10mg374,00€25mg562,00€50mg775,00€100mg1.035,00€500mgA consultarAnti-p53 Antibody (2V863)
Anti-p53 Antibody (2V863) is a Mouse antibody targeting p53. Anti-p53 Antibody (2V863) can be used in ELISA,ELISA(Det).Forma y color:Odour LiquidNSC348884
CAS:NSC348884, a nucleophosmin inhibitor, disrupts oligomers, induces apoptosis, and inhibits cancer cell growth (IC50: 1.7-4.0 μM).Fórmula:C38H40N10Pureza:98.69% - 99.91%Forma y color:SolidPeso molecular:636.79Ref: TM-T6909
2mg42,00€5mg62,00€10mg96,00€25mg180,00€50mg296,00€100mg427,00€500mg938,00€1mL*10mM (DMSO)85,00€Benzonitrile, 3,3'-[(2-oxo-1,3-cyclohexanediylidene)dimethylidyne]bis-
CAS:Benzonitrile, 3,3'-[(2-oxo-1,3-cyclohexanediylidene)dimethylidyne]bis- (9CI) is an inhibitor of p53 with an IC50 value of 0.35 μMFórmula:C22H16N2OPureza:99.18%Forma y color:SolidPeso molecular:324.38Ref: TM-T9129
1mg52,00€5mg107,00€10mg158,00€25mg259,00€50mg374,00€100mg523,00€200mg710,00€1mL*10mM (DMSO)111,00€cjoc42
CAS:Cjoc42 blocks gankyrin to prevent p53 reduction, aiding cancer prevention and DNA damage response.Fórmula:C20H21N3O5SPureza:98.54%Forma y color:SolidPeso molecular:415.46Ref: TM-T27029
1mg64,00€5mg140,00€10mg205,00€25mg368,00€50mg552,00€100mg770,00€200mg1.035,00€1mL*10mM (DMSO)160,00€Proteasome inhibitor IX
CAS:Proteasome inhibitor IX (PS-IX) is an inhibitor of chymotrypsin-like activity of the 20S proteasome (IC50 ~1 μM).Fórmula:C20H21B2NO5Pureza:98.7%Forma y color:SolidPeso molecular:377.01KCC-07
CAS:KCC-07: Selective, potent, brain-penetrant MBD2 inhibitor with anticancer effects, blocking MBD2-DNA binding and activating BAI1 signaling.Fórmula:C14H11N3OSPureza:98.86% - 99.01%Forma y color:SolidPeso molecular:269.32Ref: TM-T8554
1mg40,00€2mg52,00€5mg79,00€10mg124,00€25mg235,00€50mg374,00€100mg555,00€500mg1.206,00€1mL*10mM (DMSO)82,00€Tetrofosmin
CAS:Tetrofosmin is a phosphine developed to overcome the non-target uptake of radioligands by the generation of hetero-atomic compounds.Fórmula:C18H40O4P2Forma y color:SolidPeso molecular:382.46Quinacrine dihydrochloride
CAS:Quinacrine dihydrochloride (Mepacrine dihydrochloride) is the dihydrochloride salt of the 9-aminoacridine derivative quinacrine with potential antineoplasticFórmula:C23H30CLN3O·2HClPureza:98.24% - 99.72%Forma y color:Yellow Crystals Or PowderPeso molecular:472.88Lumichrome
CAS:Lumichrome, a riboflavin metabolite, influences plant growth, ascidian metamorphosis, bacterial communication, and blocks riboflavin uptake.Fórmula:C12H10N4O2Pureza:99.65% - 99.69%Forma y color:SolidPeso molecular:242.23P53R3
CAS:P53R3 is a potent reactivator of p53, effectively restoring sequence-specific DNA binding to several p53 hot spot mutants, namely p53 R175H, p53 R248W, and p53Fórmula:C32H35Cl2N5O2Pureza:97.75%Forma y color:SolidPeso molecular:592.56Unesbulin
CAS:Unesbulin (PTC596) is an orally active and selective inhibitor of B-cell-specific Moloney murine leukemia virus integration site 1 (BMI-1).Fórmula:C19H13F5N6Pureza:98.71%Forma y color:SolidPeso molecular:420.34YK-3-237
CAS:YK-3-237 (B-[2-Methoxy-5-[(1E)-3-oxo-3-(3,4,5-trimethoxyphenyl)-1-propen-1-yl]phenyl]boronic acid) reduces acetylation of mtp53 and exhibits anti-proliferativeFórmula:C19H21BO7Pureza:99.47%Forma y color:SolidPeso molecular:372.18Ref: TM-T9320
2mg40,00€5mg60,00€10mg87,00€25mg180,00€50mg305,00€100mg535,00€200mg690,00€500mg1.074,00€1mL*10mM (DMSO)66,00€XI-006
CAS:NSC-207895 (XI-006) suppresses MDMX with IC50 of 2.5 μM, leading to enhanced p53 stabilization/activation and DNA damage, and regulates MDM2, an E3 ligase.Fórmula:C11H13N5O4Pureza:99.12%Forma y color:SolidPeso molecular:279.25Ref: TM-T6610
1mg56,00€2mg81,00€5mg119,00€10mg187,00€25mg432,00€50mg638,00€100mg908,00€500mg1.825,00€1mL*10mM (DMSO)114,00€
![Benzonitrile, 3,3'-[(2-oxo-1,3-cyclohexanediylidene)dimethylidyne]bis-](/_next/image/?url=https%3A%2Fstatic.cymitquimica.com%2Fproducts%2FTM%2Fthumb-webp%2FT9129.webp&w=3840&q=75)
