Caspasa
Los inhibidores de caspasas son compuestos que bloquean la actividad de las caspasas, una familia de proteasas que son ejecutores centrales de la apoptosis. Las caspasas escinden sustratos específicos dentro de la célula para desencadenar el proceso apoptótico, lo que conduce a la muerte celular programada. Los inhibidores de caspasas se utilizan para estudiar los mecanismos de la apoptosis, así como para prevenir la muerte celular no deseada en varios modelos de investigación. Estos inhibidores también se exploran en contextos terapéuticos para proteger las células de la apoptosis en enfermedades como la neurodegeneración. En CymitQuimica, ofrecemos una amplia gama de inhibidores de caspasas de alta calidad para apoyar su investigación en apoptosis, muerte celular y campos relacionados.
Productos de "Caspasa"
Ordenar por
Dehydrocorydaline nitrate
CAS:DHC curbs antibody and cell-mediated allergies, inhibits mitochondrial potential in macrophages, and has antinociceptive, anti-inflammatory effects.Fórmula:C22H24N2O7Pureza:99.79%Forma y color:SolidPeso molecular:428.44Lobaplatin
CAS:Lobaplatin (D-19466) (D-19466) is a diastereometric mixture of platinum(II) complexe.Fórmula:C9H18N2O3PtPureza:98.00%Forma y color:SolidPeso molecular:397.33BOC-D-FMK
CAS:Boc-D-FMK is an irreversible, cell-permeable, and broad-spectrum caspase inhibitor and inhibits apoptosis stimulated by TNF-α (IC50: 39 μM).Fórmula:C11H18FNO5Pureza:98%Forma y color:SolidPeso molecular:263.26Ref: TM-T10580
1mg51,00€5mg144,00€10mg210,00€25mg400,00€50mg603,00€100mg840,00€1mL*10mM (DMSO)139,00€CASP3 Activator 1541
CAS:CASP3 Activator 1541 is an activator of the proenzyme forms of caspase-3, and induces cell death.Fórmula:C24H17N3O4Pureza:98.84%Forma y color:SolidPeso molecular:411.41Ac-VRPR-AMC
CAS:Ac-VRPR-AMC is a fluorogenic substrate for metacaspase activity assays, facilitating the detection and measurement of metacaspase activity [1].Fórmula:C34H51N11O7Pureza:98%Forma y color:SolidPeso molecular:725.84Almorexant hydrochloride
CAS:Almorexant hydrochloride (ACT 078573 hydrochloride) is a dual orexin receptor antagonist that induces apoptosis and can be used to study sleep disorders.Fórmula:C29H32ClF3N2O3Pureza:99.85%Forma y color:SolidPeso molecular:549.02Phenoxodiol
CAS:Phenoxodiol (Idronoxil) activates the mitochondrial caspase system, inhibits X-linked inhibitor of apoptosis(XIAP), disrupts FLICE inhibitory protein(FLIP)Fórmula:C15H12O3Pureza:98.07%Forma y color:SolidPeso molecular:240.25Caspase-3 activator 3
Caspase-3 activator 3 (compound 2h) effectively induces apoptosis in HL-60 and K562 cells by substantially activating caspase-3, demonstrating antileukemicPureza:98%Forma y color:Odour SolidM867
CAS:M867 is a selective, reversible caspase-3 inhibitor, possessing an IC50 of 1.4 nM and a Ki value of 0.7 nM, demonstrating anti-apoptotic activity [1].Fórmula:C27H43N7O6Pureza:98%Forma y color:SolidPeso molecular:561.67Diclofenac sodium
CAS:Diclofenac sodium (GP 45840) is a non-steroidal anti-inflammatory agent (NSAID) with antipyretic and analgesic actions.Fórmula:C14H10Cl2NNaO2Pureza:99.89% - 99.89%Forma y color:White Or Off-White PowderPeso molecular:318.13MJN68390
CAS:MJN68390 has an apparent IC50 value of 15 μM against CASP8 and shows no activity against CASP10.Fórmula:C24H28ClN3O3Pureza:99.06%Forma y color:SolidPeso molecular:441.95Caspase-3 activator 2
Caspase-3 Activator 2 (Compound 2f) is a caspase 3 activator with cytotoxic effects on HL-60 and K562 cells, exhibiting IC 50 values of 33.52 μM and 76.90 μM,Pureza:98%Forma y color:Odour SolidTerfenadine
CAS:Terfenadine, metabolized to fexofenadine by CYP3A4, is a non-sedative antihistamine targeting H1 receptors.Fórmula:C32H41NO2Pureza:98.76% - 99.75%Forma y color:SolidPeso molecular:471.67Ac-FLTD-CMK
CAS:Ac-FLTD-CMK, an abscisicin D derivative, selectively inhibits inflammatory caspases-1, -4, and -11 (IC50: 46.7 nM, 1.49 μM, 329 nM) but not caspase-3.Fórmula:C26H37ClN4O8Pureza:95.17%Forma y color:SolidPeso molecular:569.05Ac-VRPR-AMC TFA
Ac-VRPR-AMC TFA serves as a fluorogenic substrate for metacaspases, enabling the assay of metacaspase activity.Fórmula:C38H53F6N11O11Forma y color:SolidPeso molecular:953.88Diclofenac
CAS:Diclofenac: a nonsteroidal compound inhibiting COX-1 and COX-2, reducing pro-inflammatory prostaglandins.Fórmula:C14H11Cl2NO2Pureza:99.78% - 99.97%Forma y color:Crystals From Ether-Petroleum Ether SolidPeso molecular:296.15L67
CAS:L67 (DNA Ligase Inhibitor) is a competitive human DNA ligase inhibitor, inhibits DNA ligases I and III (IC50: 10 μM).Fórmula:C16H14Br2N4O4Pureza:98.34% - 99.56%Forma y color:SolidPeso molecular:486.11Chelidonic acid
CAS:Chelidonic acid, in Chelidonium majus, acts as an analgesic, antimicrobial, CNS sedative, and has anti-inflammatory properties.Fórmula:C7H4O6Pureza:99.03%Forma y color:SolidPeso molecular:184.1EP1013
CAS:EP1013 is a broad-spectrum selective inhibitor of Caspase used in the study of type 1 diabetes.Fórmula:C18H23FN2O6Pureza:98%Forma y color:SolidPeso molecular:382.38Asperosaponin VI
CAS:Asperosaponin VI, from Dipsacus asper rhizome, treats back pain, hematoma, and fractures.Fórmula:C47H76O18Pureza:98% - 99.79%Forma y color:SolidPeso molecular:929.1
