Ciclo celular / Checkpoint
Los inhibidores del ciclo celular/puntos de control son compuestos que interrumpen la progresión normal del ciclo celular, particularmente en puntos de control regulatorios clave. Estos inhibidores son cruciales para estudiar la división celular, comprender la proliferación de células cancerosas y desarrollar terapias anticancerígenas. Al dirigirse a fases específicas del ciclo celular, estos inhibidores pueden inducir la detención del ciclo celular, lo que lleva a apoptosis o senescencia en células de división rápida. En CymitQuimica, ofrecemos una amplia gama de inhibidores de alta calidad del ciclo celular/puntos de control para apoyar su investigación en biología del cáncer, biología celular y desarrollo de fármacos.
Subcategorías de "Ciclo celular / Checkpoint"
- Aurora quinasa
- CDK
- Detención del ciclo celular
- Chk
- c-Myc
- Dynamin
- DYRK
- Ferroptosis
- HSP
- Integrin
- Kinesina
- KSP
- LIM quinasa
- Asociado a microtúbulos
- PKC
- PLK
- Rho
- ROCK
- Wee1
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Productos de "Ciclo celular / Checkpoint"
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DNA Gyrase-IN-16
CAS:DNA Gyrase-IN-16 (Compound 9) is an inhibitor of DNA gyrase, with an IC50 of 1.609 μM. It exhibits antibacterial properties, effectively inhibiting S. aureus and MRSA, with a MIC of 3.125 μM for both.Fórmula:C17H15N3O3Forma y color:SolidPeso molecular:309.319LSN2839567
CAS:LSN2839567 (Abemaciclib metabolite M2) is a CDK4 and CDK6 inhibitor with anticancer activity, inhibits CDK9, and can be used in breast cancer research.Fórmula:C25H28F2N8Pureza:99.14%Forma y color:SolidPeso molecular:478.54Palbociclib hydrochloride
CAS:Palbociclib hydrochloride is the salt form of Palbociclib, a selective and orally available CDK4 and CDK6 inhibitor for breast and hepatocellular carcinoma.Fórmula:C24H31Cl2N7O2Pureza:99.89%Forma y color:SolidPeso molecular:520.46BOS-172722
CAS:BOS-172722 is an inhibitor of monopolar spindle 1 (MPS1) checkpoint(IC50 of 2 nM).Fórmula:C24H30N8OPureza:99.37%Forma y color:SolidPeso molecular:446.556-Thio-2'-Deoxyguanosine
CAS:6-Thio-2'-Deoxyguanosine (β-TGdR) is a nucleoside analog and telomerase substrate.Fórmula:C10H13N5O3SPureza:97.52%Forma y color:SolidPeso molecular:283.31Calcium N5-methyltetrahydrofolate
CAS:Calcium N5-methyltetrahydrofolate (NSC-173328) is the calcium salt of levomefolic acid, which has been proposed for treatment of cardiovascular disease andFórmula:C20H23CaN7O6Pureza:98%Forma y color:SolidPeso molecular:497.51Folinic acid calcium
CAS:Folinic acid calcium (Leucovorin Calcium) is the active metabolite of folic acid. Leucovorin is used principally as an antidote to folic acid antagonists.Fórmula:C20H21CaN7O7Pureza:100% - 99.5%Forma y color:Yellow Crystalline PowderPeso molecular:511.51Opugotamig
Opugotamig is a chimeric antibody of the half-IG G1 -κ/(scFv -κ-heavy) -h-CH2-CH3 type, specifically targeting FOLR1.Forma y color:Odour LiquidML-099
CAS:ML-099 is a pan Ras-related GTPases activator that activates Rac1, Ras, GTP-binding protein (Rab7), Rab2A and cell division cycle 42.Fórmula:C14H13NO2SPureza:99.48%Forma y color:SolidPeso molecular:259.32Ref: TM-T22991
1mg48,00€2mg64,00€5mg96,00€10mg153,00€25mg305,00€50mg487,00€100mg710,00€1mL*10mM (DMSO)94,00€15(S)-HpETE
CAS:15(S)-HpETE is a product of arachidonic acid formed in the 15-lipoxygenase pathway and inhibits angiogenesis.Fórmula:C20H32O4Forma y color:SolidPeso molecular:336.47LNA-Adenosine
CAS:LNA-Adenosine (LNA-A) is a nucleoside analogue that acts as a ligand for adenosine A3 receptors.Fórmula:C11H13N5O4Pureza:98.62%Forma y color:SolidPeso molecular:279.25Famciclovir
CAS:Famciclovir (BRL 42810) inhibits Herpes virus DNA polymerase by mimicking nucleosides.Fórmula:C14H19N5O4Pureza:99.85%Forma y color:Off-White PowderPeso molecular:321.33SMN-C3
CAS:SMN-C3 (MV8T2MCK57) is an orally active modulator of SMN2 splicing, and has the potential to treat spinal muscular atrophy (SMA).Fórmula:C24H28N6OPureza:98.21% - 99.31%Forma y color:SolidPeso molecular:416.52Ilorasertib
CAS:Ilorasertib (ABT-348) inhibits Aurora kinases A/B/C & RET, PDGFRβ, Flt1 (IC50: 1-120 nM).Fórmula:C25H21FN6O2SPureza:96.17% - 98.03%Forma y color:SolidPeso molecular:488.54DNA Gyrase-IN-12
DNA Gyrase-IN-12 (Compound 6d) is an inhibitor of DNA gyrase. It exhibits antibacterial activity with MIC values ranging from 0.031 to 0.0625 μg/mL against Vancomycin-Intermediate Staphylococcus aureus (VISA) and Enterococcus faecium.Forma y color:Odour SolidKIF18A-IN-16
CAS:KIF18A-IN-16 (Compound 15) is a polycyclic KIF18A inhibitor. It is applicable in research related to tumors, including colon cancer, breast cancer, and lung cancer.Fórmula:C30H37N5O4SForma y color:SolidPeso molecular:563.71DHX9-IN-6
CAS:DHX9-IN-6 is a highly effective ATP-dependent RNA helicase A (DHX9) inhibitor, used in cancer research.Fórmula:C23H18ClFN4O4S2Pureza:99.71%Forma y color:SolidPeso molecular:533Dencatistat
CAS:Dencatistat is a highly selective and oral cytidine triphosphate synthase 1 CTPS1 inhibitor specific.CTPS1-IN-2 for B-cell, T-cell lymphomas and solid tumors.Fórmula:C24H27N7O5SPureza:98.85%Forma y color:SolidPeso molecular:525.584-Oxofenretinide
CAS:4-Oxofenretinide (3-Keto fenretinide) , a recently identified fenretinide metabolite, induces marked G2-M cell cycle arrest and apoptosis.Fórmula:C26H31NO3Pureza:96.89%Forma y color:SolidPeso molecular:405.53Ref: TM-T4189
1mg44,00€2mg55,00€5mg79,00€10mg113,00€25mg195,00€50mg293,00€100mg528,00€1mL*10mM (DMSO)96,00€Tacaciclib
CAS:Tacaciclib is a cyclin-dependent kinase (CDK) inhibitor with observed antineoplastic activity [1].Fórmula:C30H36N6O3Pureza:98%Forma y color:SolidPeso molecular:528.65
