NF-κB
El factor nuclear kappa-light-chain-enhancer de células B activadas (NF-κB) es un factor de transcripción que regula la expresión de genes involucrados en respuestas inmunitarias, inflamación, supervivencia celular y proliferación. El NF-κB se activa en respuesta a varios estímulos, incluidos citocinas, patógenos y señales de estrés. La desregulación de la señalización de NF-κB está asociada con enfermedades inflamatorias crónicas, cáncer y trastornos autoinmunes. En CymitQuimica, ofrecemos una selección integral de moduladores de la vía NF-κB para apoyar su investigación en inflamación, oncología y regulación inmunitaria.
Productos de "NF-κB"
Ordenar por
IVMT-Rx-3
IVMT-Rx-3 is a chemical compound that serves as an inhibitor of SDCBP's targeting of the PDZ1 and PDZ2 domains of MDA-9/Syntenin.Fórmula:C69H90F3N13O24Pureza:98%Forma y color:SoildPeso molecular:1542.54Sauchinone
CAS:Sauchinone: Treats infections, prevents liver fibrosis, reduces oxidative stress, and protects skin and vascular cells.Fórmula:C20H20O6Pureza:100%Forma y color:SolidPeso molecular:356.37Gypenoside L
CAS:Gypenoside L inhibits autophagic flux and induces cell death in human esophageal cancer cells through endoplasm reticulum stress-mediated Ca2+ release.Fórmula:C42H72O14Pureza:99.42% - 99.65%Forma y color:SolidPeso molecular:801.01GSK840
CAS:GSK840 (GSK'840) is a receptor-interacting protein kinase 3 (RIP3 or RIPK3) inhibitor, which binds the RIP3 kinase domain (IC50: 0.9 nM), and inhibits kinaseFórmula:C21H23N3O3Pureza:99.48%Forma y color:SolidPeso molecular:365.43Flizasertib
CAS:Flizasertib is a serine/threonine kinase inhibitor that acts by inhibiting RIPK1, which has anti-inflammatory and therapeutic effects on immune disorders.Fórmula:C15H14FN3OPureza:100% - 99.39%Forma y color:SolidPeso molecular:271.29Adelmidrol
CAS:Adelmidrol is an anti-inflammatory ethanolamide derivative of azelaic acid.Fórmula:C13H26N2O4Pureza:99.35% - 99.73%Forma y color:SolidPeso molecular:274.36Eudebeiolide B
CAS:Eudebeiolide B, isolated from Salvia plebeia R.Fórmula:C15H18O4Pureza:98%Forma y color:SolidPeso molecular:262.3Tizoxanide
CAS:Tizoxanide (Desacetyl-nitazoxanide) is a metabolite of lamivudine.Fórmula:C10H7N3O4SPureza:98.89% - 99.28%Forma y color:SolidPeso molecular:265.25BOT-64
CAS:BOT-64 is an IKK-2 inhibitor which targets the Ser177 and/or Ser181 residues in the kinase's activation loop domain.BOT-64 is a cell-permeable benzoxathioleFórmula:C15H15NO2SPureza:99.73%Forma y color:SolidPeso molecular:273.35Ref: TM-T8705
1mg52,00€5mg116,00€10mg178,00€25mg340,00€50mg520,00€100mg702,00€200mg944,00€1mL*10mM (DMSO)107,00€BMS-066
CAS:BMS-066 is an IKKβ/Tyk2 pseudokinase inhibitor. With IC50s of 9 nM and 72 nM, respectively.Fórmula:C19H21N7O2Pureza:98%Forma y color:SolidPeso molecular:379.42Robinin
CAS:Robinin: a kaempferol-derived flavone glycoside with antibacterial, diuretic traits; minimal effect on Colo 320 MDR1/LRP resistance; detected in MCF-7 cells.Fórmula:C33H40O19Pureza:98.78% - 99.13%Forma y color:SolidPeso molecular:740.66IMD-biphenylB
CAS:IMD-biphenylB: Potent NF-κB inhibitor, curbs tumor growth with low inflammation and toxicity.Fórmula:C35H33N5O3Pureza:98%Forma y color:SolidPeso molecular:571.67Usnoflast
CAS:Usnoflast (ZYIL1) is an NLRP3 inhibitor, inhibiting NLRP3 inflammasome activation, used in neurological disease research.Fórmula:C21H29N3O3SPureza:98.79%Forma y color:SolidPeso molecular:403.54AP-1/NF-κB activation inhibitor 1
CAS:AP-1/NF-κB activation inhibitor 1 is a potent inhibitor of AP-1 and NF-κB mediated transcriptional activation ( IC 50 =1 μM), does not blocking basalFórmula:C13H11F3N4O4Pureza:100% - 99.74%Forma y color:SolidPeso molecular:344.25Ref: TM-T9656
1mg73,00€2mg96,00€5mg160,00€10mg216,00€25mg354,00€50mg525,00€100mg730,00€500mg1.483,00€1mL*10mM (DMSO)170,00€Edasalonexent
CAS:Edasalonexent (CAT-1004) is an orally available NF-κB inhibitor for the improvement of Duchenne muscular dystrophy.Fórmula:C31H42N2O3Pureza:100% - 98.69%Forma y color:SolidPeso molecular:490.68Ref: TM-T15198
1mg99,00€2mg144,00€5mg235,00€10mg376,00€25mg677,00€50mg1.064,00€1mL*10mM (DMSO)254,00€HS271
CAS:HS271 is a selective, highly potent and orally active IRAK4 inhibitor (IC50= 7.2 μM).Fórmula:C21H24F3N5O2Pureza:98.12%Forma y color:SolidPeso molecular:435.44Ref: TM-T37082
1mg62,00€2mg89,00€5mg135,00€10mg212,00€25mg368,00€50mg510,00€100mg695,00€200mg937,00€1mL*10mM (DMSO)149,00€5-Aminosalicylic Acid
CAS:5-ASA, an anti-inflammatory salicylate, treats inflammatory bowel disease, active part of sulphalazine.Fórmula:C7H7NO3Pureza:98.88% - 99.98%Forma y color:Purplish-Tan Solid PowderPeso molecular:153.14Cornuside
CAS:Cornuside boosts immunity, reduces inflammation, protects heart and liver, and guards against brain injury by modulating stress responses.Fórmula:C24H30O14Pureza:100% - 99.57%Forma y color:SolidPeso molecular:542.49Ref: TM-T4S2326
1mg96,00€5mg264,00€10mg415,00€25mg677,00€50mg935,00€100mg1.254,00€500mg2.527,00€1mL*10mM (DMSO)315,00€Ref: TM-T5S0754
5mg49,00€10mg65,00€25mg97,00€50mg153,00€100mg221,00€200mg329,00€1mL*10mM (DMSO)50,00€Isoliquiritin apioside
CAS:Isoliquiritin apioside, from Glycyrrhizae radix, inhibits MMP9, MAPK, NF-κB, reduces cancer cell invasion, angiogenesis, and fights oxidative DNA damage.Fórmula:C26H30O13Pureza:98.84% - 99.27%Forma y color:SolidPeso molecular:550.51
