Ras
Las proteínas Ras son pequeñas GTPasas que actúan como interruptores moleculares en la vía de señalización MAPK, controlando el crecimiento, la diferenciación y la supervivencia celular. Ras activado inicia una cascada de señalización que incluye Raf, MEK y ERK, lo que lleva a diversas respuestas celulares. Las mutaciones en los genes Ras son comunes en el cáncer, lo que convierte a Ras en un enfoque importante de la investigación oncológica. En CymitQuimica, ofrecemos una gama de moduladores de Ras para apoyar su investigación en biología del cáncer, transducción de señales y desarrollo terapéutico.
Productos de "Ras"
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KRAS G12C inhibitor 17
CAS:KRAS G12C inhibitor 17 is a potent KRAS G12C inhibitor.Fórmula:C24H20ClF2N3O3Pureza:98%Forma y color:SolidPeso molecular:471.88APS6-45
CAS:APS6-45 inhibits RAS/MAPK signaling and exhibits anti-tumor activity.Fórmula:C23H16F8N4O3Pureza:99.39%Forma y color:SolidPeso molecular:548.39Ref: TM-T8843
2mg39,00€5mg88,00€10mg127,00€25mg250,00€50mg401,00€100mg615,00€200mg830,00€1mL*10mM (DMSO)97,00€ML-099
CAS:ML-099 is a pan Ras-related GTPases activator that activates Rac1, Ras, GTP-binding protein (Rab7), Rab2A and cell division cycle 42.Fórmula:C14H13NO2SPureza:99.48%Forma y color:SolidPeso molecular:259.32Ref: TM-T22991
1mg48,00€2mg64,00€5mg96,00€10mg153,00€25mg305,00€50mg487,00€100mg710,00€1mL*10mM (DMSO)94,00€KRas G12C inhibitor 2
CAS:KRas G12C inhibitor 2 is a compound that inhibits KRas G12C.Fórmula:C32H37N7O3Pureza:98%Forma y color:SolidPeso molecular:567.68SCH54292
CAS:SCH-54292 is a GDP exchange inhibitor.Fórmula:C24H28N2O9SPureza:95.65%Forma y color:SolidPeso molecular:520.55pan-KRAS-IN-4
CAS:Pan-KRAS-IN-4 (compound 5) is a potent KRAS inhibitor, demonstrating IC50 values of 0.37 nM for Kras G12C and 0.19 nM for Kras G12V [1].Fórmula:C36H34F2N6O3Pureza:98%Forma y color:SolidPeso molecular:636.69KRas G12C inhibitor 1
CAS:KRas G12C inhibitor 1 is a compound that inhibits KRas G12C.Fórmula:C31H38N6O3Pureza:98%Forma y color:SolidPeso molecular:542.67Salirasib
CAS:Salirasib: Competitive PPMTase inhibitor, blocks Ras methylation, potential cancer treatment, Ki=2.6 μM.Fórmula:C22H30O2SPureza:99.45%Forma y color:SolidPeso molecular:358.54Ref: TM-T6163
5mg35,00€10mg52,00€25mg96,00€50mg159,00€100mg221,00€200mg364,00€500mg597,00€1mL*10mM (DMSO)59,00€TH-Z827
CAS:TH-Z827 is a mutant-selective inhibitor targeting KRAS(G12D) with an IC50 of 2.4 μM, demonstrating specificity by not binding to KRAS(WT) or KRAS(G12C).Fórmula:C30H38N6OPureza:98%Forma y color:SolidPeso molecular:498.66KRAS inhibitor-6
CAS:KRAS inhibitor-6 is a potent KRAS G12C inhibitor.Fórmula:C27H30ClF2N5O3Pureza:98%Forma y color:SolidPeso molecular:546.01KRAS G12C inhibitor 58
CAS:KRAS G12C inhibitor 58 is utilized in cancer research as an inhibitor of the KRAS G12C mutation [1].Fórmula:C51H64ClF4N9O8SPureza:98%Forma y color:SolidPeso molecular:1074.62Lonafarnib
CAS:Lonafarnib (Sch66336) is an orally bioavailable FPTase inhibitor for H-ras, K-ras-4B, and N-ras (IC50: 1.9/5.2/2.8 nM).Fórmula:C27H31Br2ClN4O2Pureza:98% - 99.04%Forma y color:SolidPeso molecular:638.82KRAS G12C inhibitor 15
CAS:KRAS G12C inhibitor 15 is a potent KRAS G12C inhibitor .Fórmula:C25H21ClF2N4O3Pureza:98%Forma y color:SolidPeso molecular:498.91ASP2453
CAS:ASP2453 is a potent, selective and covalent inhibitor of KRAS G12C.Fórmula:C40H48F3N7O4Pureza:96.57%Forma y color:SolidPeso molecular:747.85pan-KRAS-IN-2
CAS:Pan-KRAS-IN-2 (compound 6) is a broad-spectrum KRAS inhibitor exhibiting potent activity with IC50 values of ≤10 nM against KRAS wild type and its mutants (G12DFórmula:C34H34F2N4O3Pureza:98%Forma y color:SolidPeso molecular:584.66MRTX1133
CAS:View and buy MRTX1133 from TargetMol.MRTX1133 is a potent, selective, and noncovalent inhibitor of KRAS G12D.Fórmula:C33H31F3N6O2Pureza:97.39% - 99.10%Forma y color:SolidPeso molecular:600.63Ref: TM-T9303
1mg187,00€5mg399,00€10mg612,00€25mg944,00€50mg1.320,00€100mg1.730,00€200mg2.337,00€1mL*10mM (DMSO)530,00€ACBI3
CAS:ACBI3 is a selective pan-KRAS degrader with anticancer activity that degrades oncogenic KRAS. ACBI3 inhibits the growth of most cancer cell lines driven by KRAS mutations.Fórmula:C50H62N14O6S2Pureza:99.24%Forma y color:SolidPeso molecular:1019.25Sevelamer Carbonate
CAS:Sevelamer carbonate, a non-absorbed polymer, binds phosphate with carbonate instead of chloride.Fórmula:(C3H7N·C3H5ClO)x·xCH2O3Pureza:98%Forma y color:SolidPeso molecular:211.64RBC8
CAS:RBC8 is a specific GTPases RalA/RalB inhibitor by inhibiting the binding of Ral to its effector RALBP1, no inhibition on the GTPases RhoA and Ras.Fórmula:C25H20N4O3Pureza:98.44% - 99.81%Forma y color:SolidPeso molecular:424.45Ref: TM-T6634
1mg48,00€5mg92,00€10mg156,00€25mg298,00€50mg472,00€100mg687,00€200mg938,00€1mL*10mM (DMSO)97,00€Deltarasin
CAS:Deltarasin is a small molecular inhibitor of KRAS-PDEδ interaction with Kd of 38 nM for binding to purified PDEδ.Fórmula:C40H37N5OPureza:99.06%Forma y color:SolidPeso molecular:603.75
