PDE
Las fosfodiesterasas (PDEs) son enzimas que hidrolizan nucleótidos cíclicos, como el AMPc y el GMPc, en sus formas inactivas, desempeñando un papel clave en la regulación de las vías de señalización intracelular. Los inhibidores de PDE se utilizan en el tratamiento de diversas afecciones, como enfermedades cardiovasculares, disfunción eréctil y trastornos respiratorios, debido a su capacidad para modular los niveles de nucleótidos cíclicos. En CymitQuimica, ofrecemos una gama de inhibidores de PDE para apoyar su investigación en señalización celular, farmacología y desarrollo terapéutico.
Productos de "PDE"
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Sildenafil Mesylate
CAS:Sildenafil Mesylate is a mesylate form of Sildenafil, an inhibitor of Phosphodiesterase 5.Fórmula:C22H30N6O4S·xCH4O3SPureza:99.84%Forma y color:SolidPeso molecular:570.68Roflumilast N-oxide
CAS:Roflumilast N-oxide is an inhibitor of PDE type 4.Fórmula:C17H14Cl2F2N2O4Pureza:99.55% - 99.65%Forma y color:SolidPeso molecular:419.21Ref: TM-T4462
1mg35,00€2mg52,00€5mg74,00€10mg99,00€25mg170,00€50mg274,00€100mg350,00€500mg840,00€1mL*10mM (DMSO)69,00€PAT-048
CAS:PAT-048 is an effective and selective autotaxin inhibitor.Fórmula:C22H18ClF2N3O2SPureza:98%Forma y color:SolidPeso molecular:461.912-(Hydroxymethyl)pyridine
CAS:2-(Hydroxymethyl)pyridine (Piconol) is an intermediate for the synthesis of the stimulant laxative bisacodyl, and as a pyridinol with hypoglycemic activity.Fórmula:C6H7NOPureza:99.79%Forma y color:Clear Light Yellow To Orange Liquid LiquidPeso molecular:109.13Zaprinast
CAS:Zaprinast is a cGMP-selective phosphodiesterase (PDE) inhibitor and a GPR35 agonist.Fórmula:C13H13N5O2Pureza:99.73% - 99.77%Forma y color:White To Off White PowderPeso molecular:271.27Cilostamide
CAS:Cilostamide (OPC3689) is a selective phosphodiesterase (PDE)3A and PDE3B inhibitor(IC50 values of 27 and 50 nM, respectively)Fórmula:C20H26N2O3Pureza:98.87%Forma y color:White To Off-White SolidPeso molecular:342.43Irsogladine
CAS:Irsogladine (Dicloguamine) is an anti-ulcer agent that promotes gap junction intercellular communication via M1 muscarinic acetylcholine receptor binding.Fórmula:C9H7Cl2N5Pureza:99.74% - 99.91%Forma y color:White Or Colorless Crystal Or Crystalline Powder Odorless Slightly BitterPeso molecular:256.09uk-50001
CAS:UK-50001 is a PDE4 inhibitor for treating inflammation, allergies, respiratory issues, and wounds.Fórmula:C26H24F3N3O4Pureza:99.90%Forma y color:SolidPeso molecular:499.48Ref: TM-T67815
1mg159,00€5mg380,00€10mg570,00€25mg912,00€50mg1.216,00€100mg1.663,00€500mg3.315,00€1mL*10mM (DMSO)470,00€AWD 12-281
CAS:AWD 12-281 is a PDE4 inhibitor with anti-inflammatory activity and bronchodilator activity for the study of chronic obstructive pulmonary disease (COPD).Fórmula:C22H14Cl2FN3O3Pureza:99.55% - 99.95%Forma y color:SolidPeso molecular:458.27Mopidamol
CAS:Mopidamol (RA 233) is a phosphodiesterase inhibitor, a dipyridamole derivative, with anticancer activity that prevents retinal vascular defects in experimentalFórmula:C19H31N7O4Pureza:99.42% - 99.51%Forma y color:SolidPeso molecular:421.49Deltasonamide 2 hydrochloride
Deltasonamide 2 hydrochloride is a competitive high-affinity PDEδ inhibitor with a Kd of approximately 385 pM.Fórmula:C30H40Cl2N6O4S2Pureza:98%Forma y color:SolidPeso molecular:683.71MBCQ
CAS:MBCQ is an inhibitor of cGMP-specific phosphodiesterase PDE5.Fórmula:C16H12ClN3O2Pureza:99.45%Forma y color:SolidPeso molecular:313.74Ref: TM-T21965
5mg47,00€10mg80,00€25mg145,00€50mg233,00€100mg335,00€200mg467,00€1mL*10mM (DMSO)49,00€Tofimilast
CAS:Tofimilast (CP-325366), a PDE4 inhibitor, is used potentially for the treatment of asthma and chronic obstructive pulmonary disease.Fórmula:C18H21N5SPureza:99.94%Forma y color:SolidPeso molecular:339.46Mirodenafil
CAS:Mirodenafil is a PDE-5 inhibitor developed for the treatment of erectile dysfunction.Fórmula:C26H37N5O5SPureza:99.89%Forma y color:SolidPeso molecular:531.67Ref: TM-T16079
2mg35,00€5mg52,00€10mg79,00€25mg134,00€50mg210,00€100mg338,00€200mg497,00€1mL*10mM (DMSO)60,00€ONO-8430506
CAS:ONO-8430506 is an orally available, potent autotaxin (ATX)/ENPP2 inhibitor (IC90: 100 nM) that inhibits ATX activity in mouse plasma.Fórmula:C27H28FN3O3Pureza:97.05%Forma y color:SolidPeso molecular:461.53Ref: TM-T38759
1mg156,00€5mg368,00€10mg509,00€25mg770,00€50mg1.035,00€100mg1.396,00€200mg1.882,00€1mL*10mM (DMSO)409,00€Dipyridamole
CAS:Dipyridamole (Persantin) is a Platelet Aggregation Inhibitor. The physiologic effect of dipyridamole is by means of Decreased Platelet Aggregation.Fórmula:C24H40N8O4Pureza:99.47% - 99.84%Forma y color:SolidPeso molecular:504.63Z-HA155
CAS:Z-HA155 (CS-963) selectively and potently inhibits autotaxin with an IC50 of 5.7 nM.Fórmula:C24H19BFNO5SPureza:98.28%Forma y color:SolidPeso molecular:463.29Ref: TM-T11533
1mg49,00€2mg65,00€5mg97,00€10mg154,00€25mg298,00€50mg487,00€100mg692,00€1mL*10mM (DMSO)106,00€Pimobendan
CAS:Pimobendan (UD-CG 115 BS) is a selective inhibitor of PDE3 (IC50: 0.32 μM).Fórmula:C19H18N4O2Pureza:99.91%Forma y color:SolidPeso molecular:334.37Ref: TM-T1708
2mg38,00€5mg60,00€10mg87,00€25mg162,00€50mg274,00€100mg406,00€500mg920,00€1mL*10mM (DMSO)66,00€Sulmazole
CAS:Sulmazole (AR-L 115-BS) is a small molecule Sulmazole is a small molecule cGMP-PDE inhibitor.Sulmazole is a competitive inhibitor of A1 adenosine receptors.Fórmula:C14H13N3O2SPureza:99.64%Forma y color:SolidPeso molecular:287.34D159687
CAS:D159687 is a selective PDE4D inhibitor,had a procognitive profile as it improved memory in the novel object recognition test but had no antidepressant benefit.Fórmula:C21H19ClN2O2Pureza:97.57%Forma y color:SolidPeso molecular:366.84
