Fosfolipasa
Las fosfolipasas son un grupo de enzimas que hidrolizan fosfolípidos en ácidos grasos y otras sustancias lipofílicas, desempeñando un papel crítico en la biología de las membranas y la generación de moléculas de señalización. Los inhibidores de fosfolipasas se utilizan para estudiar su papel en enfermedades inflamatorias, trastornos cardiovasculares y neurodegeneración. Estos inhibidores también son valiosos para explorar las vías de señalización de lípidos y sus implicaciones en los mecanismos de enfermedades. En CymitQuimica, ofrecemos una variedad de inhibidores de fosfolipasas para apoyar su investigación en inflamación, metabolismo de lípidos y señalización celular.
Productos de "Fosfolipasa"
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hnps-PLA Inhibitor
CAS:Hnps-PLA Inhibitor is an inhibitor of human nonpancreatic secretory Phospholipase A (hnps-PLA).Fórmula:C21H21N3O4Pureza:98.95%Forma y color:SolidPeso molecular:379.41Ref: TM-T4192
1mg56,00€2mg81,00€5mg119,00€10mg202,00€25mg341,00€50mg509,00€100mg725,00€1mL*10mM (DMSO)137,00€RHC 80267
CAS:RHC 80267 (U-57908) is a selective inhibitor of DAGL (IC50 : 4 μM in canine platelets)Fórmula:C20H34N4O4Pureza:99.54%Forma y color:White SolidPeso molecular:394.51Compound 48/80 trihydrochloride
CAS:Compound 48/80 trihydrochloride (C48/80 trihydrochloride) 是 N-甲基对甲氧基苯乙胺和甲醛发生缩合反应后的混合物。Compound 48/80 trihydrochloride 是一种肥大细胞 (mast cell) 脱颗粒剂和组胺 (histamine) 释放剂。Compound 48/80 trihydrochloride 对人血小板磷脂酰肌醇特异性磷脂酶 C (phosphatidylinositol-specific phospholipase C) 活性有抑制作用。Fórmula:C32H48Cl3N3O3Pureza:98%Forma y color:SolidPeso molecular:629.1Rilapladib
CAS:Rilapladib (SB 659032) is a selective inhibitor of Lipoprotein-Associated Phospholipase A2(Lp-PLA2, IC50 = 230 pM) and an antagonist of the platelet activatingFórmula:C40H38F5N3O3SPureza:97.29%Forma y color:SolidPeso molecular:735.8Ref: TM-T16751
1mg93,00€5mg227,00€10mg369,00€25mg622,00€50mg885,00€100mg1.206,00€1mL*10mM (DMSO)369,00€CAY10594
CAS:CAY10594, a PLD2 inhibitor, mitigates acetaminophen liver damage via the p-GSK-3β/JNK pathway.Fórmula:C26H28N4O2Pureza:98%Forma y color:SolidPeso molecular:428.53Melittin
CAS:Melittin: principal bee venom toxin, 26 amino acids, activates low-weight PLA2, not high-weight PLA2.Fórmula:C131H229N39O31Pureza:98.37% - 99.14%Forma y color:SolidPeso molecular:2846.46RPI-1
CAS:RPI-1 is a competitive, potent ATP-dependent Ret kinase inhibitor.Fórmula:C17H15NO4Pureza:98.28% - ≥95%Forma y color:SolidPeso molecular:297.31DPTIP
CAS:DPTIP is an effective inhibitor of neutral sphingomyelinase 2 with an IC50 value of 30 nM.Fórmula:C21H18N2O3SPureza:98.80%Forma y color:SolidPeso molecular:378.44Ref: TM-T60043
1mg48,00€2mg63,00€5mg96,00€10mg153,00€25mg298,00€50mg487,00€100mg710,00€1mL*10mM (DMSO)96,00€5-HT1A modulator 1
CAS:5-HT1A modulator 1 displays very high affinities for the 5-HT1A, α1-adrenergic receptor, and D2 receptor (IC50s = 2 nM, 10 nM, and 40 nM).Fórmula:C21H25N3O2SPureza:99.66%Forma y color:SolidPeso molecular:383.51(E/Z)-Polydatin
CAS:(E/Z)-Polydatin, a resveratrol glycoside from Picea/Polygonum, in grapes & chocolate, has anti-inflammatory and anti-cancer properties.Fórmula:C20H22O8Pureza:98.78% - 99.16%Forma y color:SolidPeso molecular:390.38Darapladib
CAS:Darapladib (SB-480848) is a lipoprotein-associated phospholipase A2 (Lp-PLA2) inhibitor with an IC50 value of 0.25 nM.Cost-effective and quality-assured.Fórmula:C36H38F4N4O2SPureza:100% - 99.82%Forma y color:SolidPeso molecular:666.77Ref: TM-T6109
1mg52,00€2mg70,00€5mg96,00€10mg169,00€25mg329,00€50mg535,00€100mg747,00€500mg1.510,00€1mL*10mM (DMSO)154,00€ASM-IN-3
CAS:ASM-IN-3 (Compound 21b) is a selective acid sphingomyelinase (ASM) inhibitor that can penetrate the blood-brain barrier, with an IC50 of 3.37 μM against purified human ASM. By inhibiting ASM activity in the hippocampus and promoting neurogenesis, ASM-IN-3 alleviates depressive-like behavior in reserpine-induced depressive rats.Fórmula:C17H13ClN2O4Forma y color:SolidPeso molecular:344.75Desketoraloxifene
CAS:Desketoraloxifene is a selective estrogen receptor modulator, inhibiting mammalian PLD (PLD1 and PLD2).Fórmula:C27H27NO3SPureza:98%Forma y color:SolidPeso molecular:445.57Bromoenol lactone
CAS:NeurokininBromoenol lactone ((6E)-Bromoenol lactone) is an iPLA2β and serine protease inhibitor that attenuates nicotine-induced breast cancer cell proliferation.Fórmula:C16H13BrO2Forma y color:SolidPeso molecular:317.18Tanshinone I
CAS:Tanshinone I (Tanshinone A), an active principle isolated from the herbal medicine Salvia miltiorrhiza, displays cytotoxicity against tumor cells.Fórmula:C18H12O3Pureza:98.31% - 98.70%Forma y color:SolidPeso molecular:276.291-Naphthaleneacetic acid potassium salt
CAS:1-Naphthaleneacetic acid potassium salt (1-NAA Potassium Salt) is a synthetic phytogrowth hormone that promotes plant growth and a PLA2 inhibitor.Fórmula:C12H9O2·KPureza:97.68%Forma y color:Off-White To Beige PowderPeso molecular:224.3ML-095 hydrochloride
CAS:ML-095 hydrochloride (CID-25067483 hydrochloride) is a specific placental alkaline phosphatase inhibitor.Fórmula:C13H15ClN2O3Pureza:98.18%Forma y color:SolidPeso molecular:282.72Ref: TM-T21969
2mg38,00€5mg58,00€10mg96,00€25mg170,00€50mg298,00€100mg432,00€200mg607,00€1mL*10mM (DMSO)64,00€Halobetasol propionate
CAS:Halobetasol propionate (BMY-30056) is the salt of halobetasol, a synthetic corticosteroid with anti-inflammatory, antipruritic, and vasoconstrictor activities.Fórmula:C25H31ClF2O5Pureza:99.89%Forma y color:Distributed As 0 05% OintmentPeso molecular:484.96AA26-9
CAS:AA26-9 is an effective and broad-spectrum inhibitor of serine hydrolase.Fórmula:C7H10N4OPureza:99.88%Forma y color:SolidPeso molecular:166.18Ref: TM-T3990
1mg37,00€2mg52,00€5mg79,00€10mg119,00€25mg210,00€50mg350,00€100mg522,00€1mL*10mM (DMSO)87,00€VU533
CAS:VU533 is a NAPE-PLD activator, EC50=0.30 µM, boosts macrophage activity, potential in cardiometabolic diseases.Fórmula:C21H22FN3O3S2Pureza:99.08%Forma y color:SolidPeso molecular:447.55
