Receptor 5-HT
Los receptores 5-HT, también conocidos como receptores de serotonina, son un grupo de receptores acoplados a proteínas G (GPCR) que median los efectos de la serotonina, un neurotransmisor involucrado en la regulación del estado de ánimo, la ansiedad, el sueño, el apetito y otros procesos fisiológicos. Estos receptores se dividen en varios subtipos, cada uno con funciones y propiedades farmacológicas distintas. Los moduladores de los receptores 5-HT se estudian ampliamente por su papel en el tratamiento de la depresión, los trastornos de ansiedad y otras afecciones neuropsiquiátricas. En CymitQuimica, ofrecemos una gama de moduladores de receptores 5-HT de alta calidad para apoyar su investigación en neurofarmacología, trastornos del estado de ánimo y señalización GPCR.
Productos de "Receptor 5-HT"
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Mirtazapine
CAS:Mirtazapine is a unique tetracyclic antidepressant, may cause temporary liver enzyme elevation, and is linked to rare liver injury.Fórmula:C17H19N3Pureza:99.98%Forma y color:SolidPeso molecular:265.35PRX933 hydrochloride
CAS:PRX933 hydrochloride (GW876167 hydrochloride) is an agonist of 5-HT2C receptor and can be used in studies about hypertension acute treatment.Fórmula:C16H22ClN5O2Pureza:97.99% - 99.72%Forma y color:SolidPeso molecular:351.84Ref: TM-T12565
1mg356,00€5mg568,00€10mg907,00€25mg1.339,00€50mg1.815,00€100mg2.432,00€1mL*10mM (DMSO)652,00€Iprindole
CAS:Iprindole, a tricyclic indole antidepressant, is a dual weak inhibitor of noradrenaline and 5-HT uptake [1].Fórmula:C19H28N2Pureza:99.06%Forma y color:SolidPeso molecular:284.44Ref: TM-T37015
2mg37,00€5mg52,00€10mg80,00€25mg154,00€50mg266,00€100mg455,00€200mg652,00€1mL*10mM (DMSO)84,00€MDL 100009
CAS:MDL 100009, the S-enantiomer of MDL 100151 and the opposite enantiomer of MDL 100907, is a selective antagonist of 5-HT2A.Fórmula:C22H28FNO3Pureza:98.96%Forma y color:SolidPeso molecular:373.46Ref: TM-T22359
1mg148,00€2mg188,00€5mg283,00€10mg424,00€25mg655,00€50mg883,00€100mg1.169,00€200mg1.596,00€1mL*10mM (DMSO)335,00€Tropisetron
CAS:Tropisetron (ICS 205-930) is an α7-nicotinic receptor agonist and 5-HT3 receptor antagonist with Kis of 6.9 nM and 5.3 nM, respectively.Fórmula:C17H20N2O2Pureza:99.95%Forma y color:White SolidPeso molecular:284.35Flucopride
CAS:Flucopride (Compound 4a) acts as an acetylcholinesterase inhibitor (AChE) with an IC50 value of 24 nM and serves as a partial agonist for the human 5-HT4 receptor (5-HT4R) with a Ki of 9.6 nM for (h)5-HT4R. It promotes non-amyloidogenic processing of APP in COS-7 cells transiently expressing (h)5-HT4R with an EC50 of 23.0 nM. Flucopride is also likely to exhibit significant gastrointestinal tract (GIT) penetration and blood-brain barrier (BBB) permeability, as determined in PAMPA experiments.Fórmula:C22H33FN2O2Forma y color:SolidPeso molecular:376.51GR 46611
CAS:GR 46611 is a selective 5-HT1B and 5-HT1D receptor agonist and can be used in studies about the treatment of epilepsy.Fórmula:C23H27N3O2Pureza:99.9%Forma y color:SolidPeso molecular:377.48Sertindole
CAS:Sertindole, atypical antipsychotic, targets D2, 5-HT1D, 5-HT2A, 5-HT2C receptors (Kds: 2.7, 20, 0.14, 6 nM).Fórmula:C24H26ClFN4OPureza:99.74%Forma y color:Off-White To Pale Yellow SolidPeso molecular:440.94Xanthotoxol
CAS:Xanthotoxol (Psoralen) is a bioactive furocoumarin with anti-inflammatory, antioxidant, 5-HT antagonist, and neuroprotective properties.Fórmula:C11H6O4Pureza:99.97%Forma y color:SolidPeso molecular:202.16SKF-83566
CAS:SKF-83566: Blood-brain permeable, orally active D1 dopamine antagonist; weaker 5-HT2 antagonist, Ki=11 nM.Fórmula:C17H18BrNOPureza:95.00% - 99.82%Forma y color:SolidPeso molecular:332.23Arotinolol
CAS:Arotinolol is a nonselective α/β-adrenergic receptor blocker and a vasodilating β-blocker. Arotinolol also shows potency for inhibiting the binding of the radioligand [125I-ICYP] to [5HT1B-serotonergic] receptor sites. It is an antihypertensive agent.Fórmula:C15H21N3O2S3Forma y color:White SolidPeso molecular:371.54Wf-516
CAS:Wf-516 is a 5-HT reuptake inhibitor (Kis: 5 nM and 40 nM for 5-HT1A receptor and 5-HT2A receptor in humans, respectively), and with potent antidepressantFórmula:C25H25Cl2N3O4Pureza:98%Forma y color:SolidPeso molecular:502.395-HT2C agonist-3
CAS:5-HT2C agonist-3 ((+)-19), a selective 5-HT2C agonist (EC 50: 24 nM, Ki: 78 nM), exhibits antipsychotic-like activity by blocking amphetamine-inducedFórmula:C19H23ClFNO2Pureza:98%Forma y color:SolidPeso molecular:351.84Puerarin
CAS:Puerarin (Kakonein), also known as Kakonein, is a member of the class of compounds known as isoflavonoid C-glycosides. It is a 5-HT2C receptor antagonist.Fórmula:C21H20O9Pureza:98.90% - 99.21%Forma y color:Yellow Brown Fine PowderPeso molecular:416.38Cilansetron
CAS:Cilansetron is an effective and selective 5-HT3 receptor antagonist that can be used for related diseases caused by colitis.Fórmula:C20H21N3OPureza:99.77% - 99.85%Forma y color:SolidPeso molecular:319.4Clothiapine
CAS:Clothiapine is an atypical antipsychotic of the dibenzothiazepine chemical class.Fórmula:C18H18ClN3SPureza:99.93%Forma y color:SolidPeso molecular:343.87GSK163090
CAS:GSK163090 is a specific and orally active 5-HT1A/B/D receptor antagonist (pKis: 9.4/8.5/9.7, and 6.3/6.7 for 5-HT1A/B/D, and dopamine D2/D3).Fórmula:C25H29N5OPureza:99.20%Forma y color:SolidPeso molecular:415.53Ref: TM-TQ0311
1mg37,00€2mg52,00€5mg80,00€10mg125,00€25mgA consultar50mgA consultar1mL*10mM (DMSO)87,00€JPC0323
JPC0323 is a dual positive allosteric modulator of the 5-HT2C and 5-HT2A receptors, featuring on-target properties, acceptable plasma exposure, and adequateFórmula:C22H43NO4Pureza:98%Forma y color:SolidPeso molecular:385.585-HT2C agonist-4
CAS:Compound 3i, a 5-HT2C agonist-4, acts as an agonist for the 5-HT2C receptor with an EC50 of 5.7 nM. It is capable of reducing locomotor activity in zebrafish larvae.Fórmula:C24H25N5OForma y color:SolidPeso molecular:399.49Risperidone
CAS:Risperidone (R 64 766) is a selective blocker of dopamine D2 receptors and serotonin 5-HT2 receptors that act as an atypical antipsychotic agent.Fórmula:C23H27FN4O2Pureza:99.73%Forma y color:Crystalline SolidPeso molecular:410.48
