Receptor 5-HT
Los receptores 5-HT, también conocidos como receptores de serotonina, son un grupo de receptores acoplados a proteínas G (GPCR) que median los efectos de la serotonina, un neurotransmisor involucrado en la regulación del estado de ánimo, la ansiedad, el sueño, el apetito y otros procesos fisiológicos. Estos receptores se dividen en varios subtipos, cada uno con funciones y propiedades farmacológicas distintas. Los moduladores de los receptores 5-HT se estudian ampliamente por su papel en el tratamiento de la depresión, los trastornos de ansiedad y otras afecciones neuropsiquiátricas. En CymitQuimica, ofrecemos una gama de moduladores de receptores 5-HT de alta calidad para apoyar su investigación en neurofarmacología, trastornos del estado de ánimo y señalización GPCR.
Productos de "Receptor 5-HT"
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MRS7925
MRS7925 (Compound 43) serves as a potent antagonist of the 5-HT2B receptor, with an inhibition constant (Ki) of 17 nM, and is utilized in the study of fibrosisFórmula:C20H26IN5O3Pureza:98%Forma y color:SolidPeso molecular:511.36Escin IB
CAS:Escin Ib inhibits gastric emptying, at least in part, mediated by capsaicin-sensitive sensory nerves, to stimulate the synthesis and/or release of dopamine, toFórmula:C55H86O24Pureza:99.09% - 99.81%Forma y color:SolidPeso molecular:1131.26Indophagolin
CAS:Indophagolin: autophagy inhibitor, IC50 140 nM; blocks P2X4, P2X1, P2X3 receptors, IC50s 2.71, 2.40, 3.49 μM.Fórmula:C19H15BrClF3N2O3SPureza:99.76%Forma y color:SolidPeso molecular:523.75Ref: TM-T8946
1mg58,00€5mg111,00€10mg170,00€25mg284,00€50mg393,00€100mg552,00€200mg748,00€1mL*10mM (DMSO)129,00€Pipamperone
CAS:Pipamperone (McN-JR 3345) binds 5-HT2A closely as receptor.Fórmula:C21H30FN3O2Pureza:99.94%Forma y color:White PowderPeso molecular:375.48Ref: TM-T12480
1mg62,00€2mg85,00€5mg119,00€10mg170,00€25mg283,00€50mg430,00€100mg622,00€1mL*10mM (DMSO)131,00€WAY208466 dihydrochloride
CAS:WAY208466 dihydrochloride is a 5-HT6 receptor agonist (EC50=7.3 nM) with antidepressant and anxiolytic activity.Fórmula:C17H20Cl2FN3O2SPureza:98.43%Forma y color:SolidPeso molecular:420.33WAY-100635 maleate
CAS:WAY-100635 Maleate is a specific and effective 5-HT receptor antagonist (IC50=0.95 nM).Fórmula:C25H34N4O2·xC4H4O4Pureza:100%Forma y color:White SolidPeso molecular:538.645Ref: TM-T3453
2mg46,00€5mg66,00€10mg95,00€25mg159,00€50mg226,00€100mg334,00€500mg807,00€1mL*10mM (DMSO)79,00€5-HT2A receptor agonist-6
CAS:5-HT2A receptor agonist-6 (compound 47) is a selective agonist of the 5-HT2A receptor with a pEC50 value of 6.58.Fórmula:C18H19N3O3Forma y color:SolidPeso molecular:325.36Niaprazine
CAS:Niaprazine is a histamine H1-receptor antagonist with marked sedative properties.Fórmula:C20H25FN4OPureza:99.5%Forma y color:SolidPeso molecular:356.44Ref: TM-T36949
2mg40,00€5mg58,00€10mg96,00€25mg144,00€50mg210,00€100mg309,00€200mg444,00€1mL*10mM (DMSO)64,00€Brexpiprazole
CAS:Brexpiprazole (OPC-34712) is a partial agonist of human 5-hydroxytryptamine (5-HT) 5-HT1A and dopamine D2 receptors.Fórmula:C25H27N3O2SPureza:99.06% - 99.96%Forma y color:SolidPeso molecular:433.57SB 243213
CAS:SB 243213 is a 5-HT2C receptor antagonist with anxiolytic and antidepressant activity used in schizophrenia and movement disorders.Fórmula:C22H19F3N4O2Pureza:100% - 100%Forma y color:SolidPeso molecular:428.41Bemesetron
CAS:Bemesetron (MDL 72222) is a selective antagonist of 5-HT3 (IC50 = 0.33 nM) with neuroprotective effects.Fórmula:C15H17Cl2NO2Pureza:97.37%Forma y color:SolidPeso molecular:314.21Prucalopride
CAS:Prucalopride (R-93877), a selective 5-HT4A/4B agonist (Ki: 2.5/8 nM), is >290x more specific for these receptors.Fórmula:C18H26ClN3O3Pureza:100%Forma y color:SolidPeso molecular:367.87Ro4368554
CAS:Ro4368554 is a selective 5-HT6 antagonist capable of crossing the blood-brain barrier. It can reverse memory deficits caused by scopolamine and tryptophan depletion. Ro4368554 is applicable for research related to memory impairments.Fórmula:C19H21N3O2SForma y color:SolidPeso molecular:355.454lumateperone Tosylate
CAS:lumateperone Tosylate (ITI-007) is a 5-HT2A receptor antagonist, a partial agonist of presynaptic D2 receptors and an antagonist of postsynaptic D2 receptors.Fórmula:C31H36FN3O4SPureza:95.83% - 98.57%Forma y color:SolidPeso molecular:565.7F 14679
CAS:F 14679 is a potent 5-HT1A agonist (pKi=10.23) with a maximum Ca2t response similar to 5-HT.Fórmula:C21H25ClF2N4OPureza:99.09%Forma y color:SolidPeso molecular:422.9FFN246
CAS:FFN246, a fluorescent probe, concurrently targets the serotonin transporter (SERT) and vesicular monoamine transporter 2 (VMAT2), exhibiting excitation andFórmula:C15H13FN2OPureza:98%Forma y color:SolidPeso molecular:256.27SB 242084
CAS:SB 242084 dihydrochloride hydrate is a psychoactive drug and research chemical which acts as a selective antagonist for the 5HT2C receptor.Fórmula:C21H19ClN4O2Pureza:99.77% - ≥98%Forma y color:SolidPeso molecular:394.85Ref: TM-T7277
1mg42,00€2mg55,00€5mg90,00€10mg115,00€25mg246,00€50mg472,00€100mg720,00€1mL*10mM (DMSO)89,00€Cisapride
CAS:Cisapride (R 51619), a 5-HT4 agonist, enhances gut peristalsis and gastric emptying, reduces reflux.Fórmula:C23H29ClFN3O4Pureza:99.77%Forma y color:White To Slightly Biege Powder SolidPeso molecular:465.95Ref: TM-T1291
5mg47,00€10mg59,00€25mg77,00€50mg99,00€100mg135,00€200mg235,00€500mg394,00€1mL*10mM (DMSO)55,00€(S)-Bexicaserin
CAS:(S)-Bexcaserin (compound 2) serves as a 5-HT2C receptor agonist, presenting research possibilities in obesity and psychiatric disorders [1].Fórmula:C15H19F2N3OPureza:98%Forma y color:SolidPeso molecular:295.33Frovatriptan succinate hydrate
CAS:Frovatriptan treats all migraine types, nausea, vomiting, light/sound sensitivity, and prevents menstrual migraines; it targets 5-HT1B/D and 5-HT7 receptors.Fórmula:C18H25N3O6Pureza:99.95%Forma y color:SolidPeso molecular:379.41
