Receptor 5-HT
Los receptores 5-HT, también conocidos como receptores de serotonina, son un grupo de receptores acoplados a proteínas G (GPCR) que median los efectos de la serotonina, un neurotransmisor involucrado en la regulación del estado de ánimo, la ansiedad, el sueño, el apetito y otros procesos fisiológicos. Estos receptores se dividen en varios subtipos, cada uno con funciones y propiedades farmacológicas distintas. Los moduladores de los receptores 5-HT se estudian ampliamente por su papel en el tratamiento de la depresión, los trastornos de ansiedad y otras afecciones neuropsiquiátricas. En CymitQuimica, ofrecemos una gama de moduladores de receptores 5-HT de alta calidad para apoyar su investigación en neurofarmacología, trastornos del estado de ánimo y señalización GPCR.
Productos de "Receptor 5-HT"
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Hypidone hydrochloride
CAS:Hypidone hydrochloride (YL0919) is a novel antidepressant candidate with dual activity as a 5-HT1A receptor agonist and a selective serotonin reuptake inhibitorFórmula:C18H23ClN2O2Pureza:99.82% - 99.93%Forma y color:SolidPeso molecular:334.84Aripiprazole
CAS:Aripiprazole (OPC-14597) is a piperazine/quinolone antipsychotic, partial agonist at 5-HT1A/D2, and antagonist at 5-HT2A.Fórmula:C23H27Cl2N3O2Pureza:99.43% - 99.62%Forma y color:Colourless Flake Crystalline SolidPeso molecular:448.39Naratriptan
CAS:Naratriptan is a selective agonist of 5-HT1 receptor and is is used for the treatment of migraine headaches.Fórmula:C17H25N3O2SPureza:99.08%Forma y color:SolidPeso molecular:335.47Metoclopramide hydrochloride
CAS:Metoclopramide hydrochloride (Metoclopramide HCl) is a selective dopamine D2 receptor antagonist, used as an antiemetic.Fórmula:C14H22ClN3O2·HClPureza:99.99%Forma y color:White To Off-White PowderPeso molecular:336.26Tiflucarbine
CAS:Tiflucarbine is a potential non-selective 5-HT agonist with antidepressant activity.Tiflucarbine dose-dependently increased the specific activity of solubleFórmula:C16H17FN2SPureza:100%Forma y color:SolidPeso molecular:288.38pCPA methyl ester hydrochloride
CAS:pCPA methyl ester HCl inhibits tryptophan hydroxylase, 5-HT synthesis, crosses blood-brain barrier, lowers central 5-HT.Fórmula:C10H13Cl2NO2Pureza:99.08% - 99.88%Forma y color:SolidPeso molecular:250.12Loxapine
CAS:Loxapine, a dibenzoxazepine antipsychotic, treats schizophrenia by blocking D2/D4 and serotonin receptors. Related to clozapine.Fórmula:C18H18ClN3OPureza:99.88%Forma y color:Pale Yellowish Crystals From Petroleum Ether SolidPeso molecular:327.815-HT2 agonist-1
CAS:Compound 24, a 5-HT2 agonist-1, selectively activates 5-HT2A, 5-HT2B, and 5-HT2C receptors with IC50 values of 10 nM, 8.3 nM, and 1.6 nM, respectively.Fórmula:C19H23ClN2O2Pureza:98%Forma y color:SolidPeso molecular:346.85Gevotroline
CAS:Gevotroline, a chemical in palm wine that can be used to treat psychosis, is a 5-HT2 receptor antagonist that can be used to study behavioral disorders.Fórmula:C19H20FN3Pureza:98.79%Forma y color:SolidPeso molecular:309.385-HT1AR/5-HT6R ligand-1
5-HT1AR/5-HT6R ligand-1 (Compound PP13) functions as a ligand for the 5-HT receptor, demonstrating high affinity for 5-HT1AR, 5-HT6R, and 5-HT7R with Ki values of 19, 69, and 198 nM, respectively. In HEK293 cells, it inhibits cAMP production with EC50 values of 1535, 488, and 53 nM for these receptors. Additionally, 5-HT1AR/5-HT6R ligand-1 exhibits antiproliferative effects on several cancer cell lines, including 1321N1, U87MG, MCF7, and AsPC-1, with IC50 values of 9.6, 13.6, 19.3, and 14.6 μM, respectively. The compound also shows antagonistic activity towards the dopamine receptor D2R, with a Ki of 1903 nM.Fórmula:C25H29ClN4O2SForma y color:SolidPeso molecular:485.04GTS-21 dihydrochloride
CAS:GTS-21 dihydrochloride (DMBX-anabaseine) is a nAChRs agonist. nAChRs are neuron receptor proteins that activated by the binding of the neurotransmitter ACh.Fórmula:C19H20N2O2·2HClPureza:100% - 99.62%Forma y color:SolidPeso molecular:381.3Ref: TM-T2663
5mg51,00€10mg85,00€25mg115,00€50mg144,00€100mg216,00€200mg325,00€500mg545,00€1mL*10mM (DMSO)57,00€4-Iodoamphetamine hydrochloride
CAS:4-Iodoamphetamine (p-Iodoamphetamine) hydrochloride is a halogenated phenethylamine characterized by the presence of an iodine atom at the para position of the phenyl group. It selectively induces serotonin release and inhibits reuptake in rat brain synaptosomes.Fórmula:C9H13ClINForma y color:SolidPeso molecular:297.56Citalopram hydrobromide
CAS:Citalopram hydrobromide (XU-62-320) , a selective serotonin reuptake inhibitor (SSRI), selectively inhibits the CNS neuronal reuptake of serotonin, therebyFórmula:C20H22BrFN2OPureza:99.81%Forma y color:White Crystalline PowderPeso molecular:405.304SB 204741
CAS:SB 204741 is a selective 5-HT2B antagonist with high affinity and pKi value of 7.1.Fórmula:C14H14N4OSPureza:99.83%Forma y color:SolidPeso molecular:286.35Eletriptan hydrobromide
CAS:Eletriptan hydrobromide (Eletriptan HBr) is an orally active agonist with specific affinity for the 5-hydroxytriptamine1B/1D receptor.Fórmula:C22H27BrN2O2SPureza:100% - 99.69%Forma y color:Tan SolidPeso molecular:463.43Ref: TM-T0216
2mg39,00€5mg57,00€10mg70,00€25mg134,00€50mg230,00€100mg373,00€200mg555,00€1mL*10mM (DMSO)63,00€Cinitapride Hydrogen Tartrate
CAS:Cinitapride Hydrogen Tartrate is a gastroprokinetic agent that acts as an antagonist of the 5-HT2 receptors and as an agonist of the 5-HT1 and 5-HT4 receptorsFórmula:C25H36N4O10Pureza:98%Forma y color:SolidPeso molecular:552.5812-Methyl-5-HT maleate
CAS:2-Methyl-5-HT maleate, a selective 5-HT3 agonist, shows anti-depressive effects.Fórmula:C15H18N2O5Pureza:98%Forma y color:SolidPeso molecular:306.31WAY-607695
CAS:WAY-607695 is a potential 5-HT1A receptor agonist.Fórmula:C13H12FNO2Pureza:99.82%Forma y color:SolidPeso molecular:233.24Rotigotine Hydrochloride
CAS:Rotigotine HCl, D3-preferential dopamine agonist, is 50x stronger than quinpirole in anti-Parkinson's efficacy.Fórmula:C19H26ClNOSPureza:99.53% - 99.56%Forma y color:Almost White To White Crystalline PowderPeso molecular:351.93D3/5-HT receptor modulator-1
CAS:D3/5-HT receptor modulator-1 (compound 5i) is a selective antagonist of the dopamine D3 and 5-HT2A receptors, and a partial agonist at the 5-HT1A receptor. It exhibits Ki values of 4.5 nM, 11.9 nM, and 15.3 nM for the dopamine D3, 5-HT2A, and 5-HT1A receptors respectively. The compound shows lower affinity for the dopamine D2 receptor, 5-HT2C receptor, and hERG channel. D3/5-HT receptor modulator-1 possesses atypical antipsychotic properties.Fórmula:C24H29N3O2Forma y color:SolidPeso molecular:391.506
