Receptor 5-HT
Los receptores 5-HT, también conocidos como receptores de serotonina, son un grupo de receptores acoplados a proteínas G (GPCR) que median los efectos de la serotonina, un neurotransmisor involucrado en la regulación del estado de ánimo, la ansiedad, el sueño, el apetito y otros procesos fisiológicos. Estos receptores se dividen en varios subtipos, cada uno con funciones y propiedades farmacológicas distintas. Los moduladores de los receptores 5-HT se estudian ampliamente por su papel en el tratamiento de la depresión, los trastornos de ansiedad y otras afecciones neuropsiquiátricas. En CymitQuimica, ofrecemos una gama de moduladores de receptores 5-HT de alta calidad para apoyar su investigación en neurofarmacología, trastornos del estado de ánimo y señalización GPCR.
Productos de "Receptor 5-HT"
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Azasetron hydrochloride
CAS:Azasetron hydrochloride (Y-25130 HCl) is a 5-HT3 receptor antagonist which is used as an anti-emetic.Fórmula:C17H20ClN3O3·HClPureza:99.50%Forma y color:SolidPeso molecular:386.27Trimipramine maleate
CAS:Trimipramine maleate, a tricyclic antidepressant, blocks serotonin and norepinephrine reuptake, boosting their levels and duration.Fórmula:C24H30N2O4Pureza:99.47%Forma y color:SolidPeso molecular:410.51Ritanserin
CAS:Ritanserin (R 55667) is a long-acting, highly potent, relatively selective, orally bioavailable 5-HT2 receptor antagonist.Cost-effective and quality-assured.Fórmula:C27H25F2N3OSPureza:99.45% - 99.89%Forma y color:SolidPeso molecular:477.57Flumexadol
CAS:Flumexadol is a selective 5-HT2C receptor agonist with an affinity (Ki) of 25 nM for the (+)-enantiomer and exhibits 40-fold selectivity over the 5-HT2A receptor. It is an orally active, non-narcotic analgesic.Fórmula:C11H12F3NOPureza:98%Forma y color:SolidPeso molecular:231.21DREADD agonist 21
CAS:DREADD agonist 21 is a potent agonist of human muscarinic acetylcholine M3 receptors (EC50=1.7 nM).Fórmula:C17H18N4Pureza:99.88%Forma y color:SolidPeso molecular:278.35Ref: TM-T11095L
2mg34,00€5mg58,00€10mg85,00€25mg140,00€50mg221,00€100mg329,00€200mg472,00€1mL*10mM (DMSO)52,00€Mosapride Citrate
CAS:Mosapride Citrate (TAK-370 citrate), a gastroprokinetic agent, utilizes as a selective 5HT4 agonist.Fórmula:C21H25ClFN3O3·C6H8O7Pureza:99.70%Forma y color:White PowderPeso molecular:614.02Itasetron
CAS:Itasetron, a 5-HT3 antagonist, prevents memory loss in rats and has antiemetic effects in cancer treatments.Fórmula:C16H20N4O2Pureza:100% - 99.63%Forma y color:SolidPeso molecular:300.364-Chloro-L-phenylalanine
CAS:4-Chloro-L-phenalanine (L-PCPA) is an inhibitor of 5-HT biosynthesis and a non-specific antagonist of tryptophan hydroxylases (TPH1 and TPH2).Fórmula:C9H10ClNO2Pureza:99.76% - 99.96%Forma y color:SolidPeso molecular:199.63Isocorynoxeine
CAS:Isocorynoxeine reduces blood pressure, dilates vessels, and guards neurons against ischemia and glutamate toxicity.Fórmula:C22H26N2O4Pureza:98% - 99.9%Forma y color:SolidPeso molecular:382.45Donitriptan
CAS:Donitriptan 是一种 5-HT 受体激动剂,对 5-HT1B 和 5-HT1D 的 pKi 分别为 9.4 和 9.3。Fórmula:C23H25N5O2Pureza:98.34%Forma y color:SolidPeso molecular:403.485-MeO-pyr-T
CAS:5-MeO-pyr-T (5-Methoxy pyrrolidinyltryptamine) acts as a 5-HT1AR agonist, exhibiting Ki values of 0.577 μM and 373 μM for 5-HT1AR and 5-HT2AR, respectively. It inhibits the reuptake of 5-HT and triggers its release. Additionally, 5-MeO-pyr-T can induce reduced motor activity.Fórmula:C15H20N2OForma y color:SolidPeso molecular:244.33PRX-07034 hydrochloride
CAS:PRX-07034 hydrochloride is a selective antagonist of 5-HT6 receptor. It has cognition and memory-enhancing properties and decreases body weight in rodents.Fórmula:C21H29Cl2N3O4SPureza:98.50%Forma y color:SolidPeso molecular:490.44Naftidrofuryl oxalate
CAS:Naftidrofuryl oxalate treats peripheral/cerebral vascular issues, boosts cell oxidation, is spasmolytic, and may block 5HT-2 serotonin receptors.Fórmula:C26H35NO7Pureza:97.12% - 98.38%Forma y color:SolidPeso molecular:473.567-Desmethyl-3-hydroxyagomelatine
CAS:7-Desmethyl-3-hydroxyagomelatine, less active than parent drug Agomelatine, is a melatonergic agonist and 5-HT2C antagonist.Fórmula:C14H15NO3Pureza:98%Forma y color:SolidPeso molecular:245.27Etoperidone
CAS:Etoperidone is an antidepressant that acts as an orally active reuptake inhibitor for serotonin (serotonin) and noradrenaline (nor-adrenaline). It demonstrates specific binding affinities (Kd) for several receptors: 36 nM at the 5-HT2 receptor, 38 nM at the α1-adrenergic receptor (α1-adrenergic receptor), 85 nM at the 5-HT1A receptor, and 570 nM at the α2-adrenergic receptor (α2-adrenergic receptor).Fórmula:C19H28ClN5OForma y color:SolidPeso molecular:377.91Org-12962
CAS:Org-12962: 5-HT2C agonist (pEC50: 7.01), anti-panic in rats, affects 5-HT2A/B (pEC50: 6.38/6.28).Fórmula:C10H11ClF3N3Pureza:98.34%Forma y color:SolidPeso molecular:265.66Perphenazine
CAS:Perphenazine (Trilafon) is a phenothiazine derivative and a dopamine antagonist with antiemetic and antipsychotic properties.Fórmula:C21H26ClN3OSPureza:99.3% - 99.72%Forma y color:SolidPeso molecular:403.97Eplivanserin
CAS:Eplivanserin (SR-46349) is an effective and selective antagonist of 5-HT2A receptor with a Kd of 1.14 nM and an IC50 value of 5.8 nM in rat cortical membrane.Fórmula:C19H21FN2O2Pureza:97.04%Forma y color:SolidPeso molecular:328.38Zotepine
CAS:Zotepine, an antipsychotic agent, is a potent antagonist of 5-HT2A, 5-HT2C, Histamine H1, α1-adrenergic, and Dopamine D2 receptors, with Kds of 2.6 nM, 3.2 nM,Fórmula:C18H18ClNOSPureza:99.78%Forma y color:SolidPeso molecular:331.86Jatrorrhizine
CAS:Jatrorrhizine (neprotin) is a protoberberine alkaloid isolated from Enantia chlorantha (Annonaceae) and other species.Fórmula:C20H20NO4Pureza:97.18% - 99.06%Forma y color:SolidPeso molecular:338.38
