Señalización citoesquelética
Los inhibidores de la señalización del citoesqueleto son compuestos que interrumpen las vías de señalización que regulan el citoesqueleto, crucial para la forma celular, la motilidad, la división y el transporte intracelular. Estos inhibidores se utilizan para estudiar la dinámica de las proteínas del citoesqueleto, como la actina y la tubulina, y su papel en procesos como la migración celular, la adhesión y la metástasis del cáncer. Los inhibidores de la señalización del citoesqueleto son valiosos en la investigación sobre biología celular, cáncer y neurobiología. En CymitQuimica, ofrecemos una amplia gama de inhibidores de la señalización del citoesqueleto de alta calidad para apoyar su investigación en estas áreas.
Productos de "Señalización citoesquelética"
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VER-49009
CAS:VER-49009 (CCT 129397) is a potent Hsp90 inhibitor(IC50 of 25 nM and Kd of 78 nM).Fórmula:C19H18ClN3O4Pureza:99.36% - 99.99%Forma y color:SolidPeso molecular:387.82Ref: TM-T3454
2mg46,00€5mg64,00€10mg92,00€25mg164,00€50mg259,00€100mg354,00€200mg500,00€1mL*10mM (DMSO)52,00€GW406108X(Z/E)
CAS:GW406108X(Z/E) is a mixture of different configurations of GW406108X, which is an inhibitor of Kinesin-12 and ULK1 .Fórmula:C20H11Cl2NO4Pureza:98.23%Forma y color:SolidPeso molecular:400.21Ref: TM-T9207L
1mg131,00€5mg286,00€10mg430,00€25mg647,00€50mg969,00€100mg1.301,00€1mL*10mM (DMSO)283,00€Valrubicin
CAS:Valrubicin (AD-32) (AD 32) inhibits TPA- and PDBu-induced PKC activation (IC50s: 0.85 and 1.25 μM) and has antitumor and anti-inflammatory activity.Fórmula:C34H36F3NO13Pureza:98.63%Forma y color:SolidPeso molecular:723.64Tubulin inhibitor 8
CAS:Tubulin inhibitor 8 blocks tubulin polymerization, stunts K562 cancer cell growth; IC50: 0.73 μM, 14 nM.Fórmula:C21H14N2O3Pureza:100% - 99.34%Forma y color:SolidPeso molecular:342.35TTBK1-IN-2
CAS:TTBK1-IN-2, a TTBK1 inhibitor with IC50s of 0.24/4.22 µM, lowers TDP-43 phosphorylation in vitro and in mice.Fórmula:C18H13ClN4OPureza:99.83%Forma y color:SoildPeso molecular:336.77Ref: TM-T60086
1mg81,00€5mg168,00€10mg240,00€25mg399,00€50mg567,00€100mg758,00€200mg1.017,00€1mL*10mM (DMSO)170,00€Pimitespib
CAS:Pimitespib (TAS-116) is an ATP-competitive and highly specific HSP90α/HSP90β inhibitor (Kis: 34.7 nM and 21.3 nM, respectively).Fórmula:C25H26N8OPureza:99.22% - 99.49%Forma y color:SolidPeso molecular:454.53P8RI acetate
P8RI acetate mimics CD31, activates CDP8RI, and suppresses the immune response by restoring CD31 pathway.Fórmula:C53H81N13O11Pureza:99.61%Forma y color:SolidPeso molecular:1076.29Paprotrain
CAS:Paprotrain ((alphaZ)-alpha-(3-Pyridinylmethylene)-1H-indole-3-acetonitrile) inhibits the ATPase activity of MKLP-2 with an IC50 of 1.35 μM and a Ki of 3.36 μM.Fórmula:C16H11N3Pureza:99.69%Forma y color:SolidPeso molecular:245.28Ref: TM-T12359
5mg48,00€10mg62,00€25mg97,00€50mg169,00€100mg250,00€200mg373,00€500mg612,00€1mL*10mM (DMSO)52,00€DDO-5936
CAS:DDO-5936 is a potent and specific HSP90-Cdc37 PPI inhibitor.Fórmula:C25H29N5O4SPureza:99.81%Forma y color:SolidPeso molecular:495.59Ref: TM-T9202
1mg37,00€5mg80,00€10mg126,00€25mg264,00€50mg389,00€100mg553,00€200mg750,00€1mL*10mM (DMSO)88,00€22-(4′-py)-JA
CAS:22-(4′-py)-JA, a semisynthetic derivative of junamycin A isolated from the Thai blue sponge (Xestospongia sp.), exhibits antimetastatic properties by inhibitingFórmula:C32H30N4O8Pureza:98%Forma y color:SolidPeso molecular:598.6Kif15-IN-1
CAS:Kif15-IN-1 is a Kif15 inhibitor with antiproliferative and potential anticancer activity, which can be used to study gastric cancer.Fórmula:C20H22N4O5SPureza:99.39% - 99.39%Forma y color:SolidPeso molecular:430.48TC-Mps1-12
CAS:TC-Mps1-12 is an effective and selective inhibitor of monopolar spindle 1 (IC50: 6.4 nM) .Fórmula:C17H20N6OPureza:98%Forma y color:SolidPeso molecular:324.38GSK215
CAS:GSK215: potent, selective PROTAC degrader of FAK (pDC50=8.4), combines FAK inhibitor VS-4718 and VHL E3 ligase binder, causes fast, lasting FAK degradation.Fórmula:C50H59F3N10O6SPureza:99.3%Forma y color:SoildPeso molecular:985.13Dioleyl phosphatidylserine
CAS:Dioleyl phosphatidylserine is a phospholipid that can activate PKC-γ (Protein Kinase C-gamma) when the Ca2+ concentration is below 0.5 μM, specifically at a concentration of 100 μM.Fórmula:C42H78NO10PForma y color:SolidPeso molecular:788.04Flumatinib mesylate
CAS:Flumatinib mesylate (HHGV678 mesylate) is a selective inhibitor of c-Abl, PDGFRβ and c-Kit, effectively overcomes drug resistance of certain KIT mutants.Fórmula:C30H33F3N8O4SPureza:99.82%Forma y color:SolidPeso molecular:658.69Ref: TM-T7861
1mg37,00€5mg88,00€10mg133,00€25mg250,00€50mg393,00€100mg628,00€500mg1.301,00€1mL*10mM (DMSO)139,00€NDNA4
NDNA4 (compound 17) is a selective Hsp90α inhibitor (IC50: 0.34 μM), characterized by its permanent charge and low membrane permeability.Fórmula:C31H35F3N2O5SPureza:98%Forma y color:SolidPeso molecular:604.68Akt-I-1,2
CAS:Akt-I-1,2 is a selective inhibitor of Akt1 and Akt2.Fórmula:C23H22ClN3Pureza:99.45%Forma y color:SolidPeso molecular:375.89Ref: TM-T23695
1mg137,00€2mg180,00€5mg269,00€10mg395,00€25mg615,00€50mg832,00€100mg1.121,00€200mg1.510,00€Hu7691
CAS:Hu7691 is an Akt inhibitor that inhibits Akt1, Akt2, and Akt3, suppresses neuroblastoma cell proliferation, and induces differentiation of neuroblastoma cells.Fórmula:C22H22ClF3N4OPureza:99.86%Forma y color:SolidPeso molecular:450.88Decursin
CAS:Decursin: potential antiepileptic, hepatoprotective, anti-cancer, anti-amnesic; affects NOX activation, PKCα/MAPK/NF-κB pathways, AChE.Fórmula:C19H20O5Pureza:100% - 97.22%Forma y color:SolidPeso molecular:328.36Ref: TM-T3S1416
1mg43,00€5mg88,00€10mg119,00€25mg259,00€50mg462,00€100mg662,00€500mg1.359,00€1mL*10mM (DMSO)87,00€Daphnetin
CAS:Daphnetin (7,8-Dihydroxycoumarin), a natural coumarin derivative, is a protein kinase inhibitor with inhibitory for EGFR (IC50: 7.67 μM), PKA (IC50: 9.33 μM),Fórmula:C9H6O4Pureza:97.47% - 99.8%Forma y color:SolidPeso molecular:178.14
