
Señalización citoesquelética
Los inhibidores de la señalización del citoesqueleto son compuestos que interrumpen las vías de señalización que regulan el citoesqueleto, crucial para la forma celular, la motilidad, la división y el transporte intracelular. Estos inhibidores se utilizan para estudiar la dinámica de las proteínas del citoesqueleto, como la actina y la tubulina, y su papel en procesos como la migración celular, la adhesión y la metástasis del cáncer. Los inhibidores de la señalización del citoesqueleto son valiosos en la investigación sobre biología celular, cáncer y neurobiología. En CymitQuimica, ofrecemos una amplia gama de inhibidores de la señalización del citoesqueleto de alta calidad para apoyar su investigación en estas áreas.
Productos de "Señalización citoesquelética"
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GRGDSP acetate(91037-75-1 free base)
GRGDSP acetate(91037-75-1 free base) is a synthetic linear RGD peptide and is an integrin inhibitor.Fórmula:C24H41N9O12Pureza:99.77%Forma y color:SolidPeso molecular:647.64Auristatin E
CAS:Auristatin E, MMAE analog, blocks tubulin polymerisation, has cytotoxic and potent antitumor effects, used in ADCs.Fórmula:C40H69N5O7Pureza:98.81%Forma y color:SolidPeso molecular:732.01SB-216
CAS:SB-216, a potent anti-cancer compound, inhibits tubulin polymerization and curbs growth in various cancer cells.Fórmula:C17H18N4O2Pureza:100%Forma y color:SolidPeso molecular:310.35Ref: TM-T60757
1mg54,00€5mg116,00€10mg188,00€25mg331,00€50mg475,00€100mg655,00€1mL*10mM (DMSO)133,00€Dynamin inhibitory peptide, myristoylated acetate
Myristoylated acetate peptide inhibits DynaMin, blocking amphiphysin binding; myristoylated TFA variant hinders endocytosis.Fórmula:C63H111N19O16Pureza:99.42%Forma y color:SolidPeso molecular:1390.67SC-10
CAS:SC-10 is a direct activator of PKC with potential antiproliferative activity, useful in leukemia research.Fórmula:C17H22ClNO2SPureza:99.24% - 99.58%Forma y color:SolidPeso molecular:339.88GRP78-IN-3
CAS:GRP78-IN-3: Potent Hsp70 blocker, selective Grp78 (HSPA5) inhib., IC50 0.59 μM, 7x more vs HspA9, 20x vs HspA2.Fórmula:C17H18N4O2SPureza:99.11%Forma y color:SoildPeso molecular:342.42ALK inhibitor 1
CAS:ALK inhibitor 1 is a selective ALK kinase inhibitor.Fórmula:C23H28BrN7O3SPureza:98.27%Forma y color:SolidPeso molecular:562.48Ref: TM-T10285
1mg52,00€5mg116,00€10mg170,00€25mg340,00€50mg472,00€100mg645,00€1mL*10mM (DMSO)143,00€KIF18A-IN-3
CAS:KIF18A-IN-3 is a KIF18A inhibitor (IC50=61 nM) that causes significant mitotic arrest and increases the number of mitotic cells in tumor tissues.Fórmula:C28H38N4O5S2Pureza:98.45%Forma y color:SolidPeso molecular:574.76Combretastatin A-1
CAS:Combretastatin A-1 is a microtubule inhibitor with anti-tumour and can be used to study liver cancer.Fórmula:C18H20O6Pureza:97.49% - 97.49%Forma y color:SolidPeso molecular:332.35Lifitegrast
CAS:Lifitegrast (SAR 1118) is a lymphocyte, function-associated antigen-1 antagonist.Fórmula:C29H24Cl2N2O7SPureza:99.39% - 99.66%Forma y color:SolidPeso molecular:615.48CGP 53353
CAS:CGP 53353 (DAPH-7) is a PKC inhibitor with inhibitory effects on PKCβII and PKCβI and can be used to study atherosclerosis.Fórmula:C20H13F2N3O2Pureza:98.11%Forma y color:SolidPeso molecular:365.33PKC-θ inhibitor
CAS:PKC-theta inhibitor is PKC-θinhibitor, with an IC50 of 12 nM.Fórmula:C20H25F3N6O3Pureza:98%Forma y color:SolidPeso molecular:454.45Ref: TM-T5423
1mg106,00€5mg250,00€10mg329,00€25mg467,00€50mg612,00€100mg944,00€200mg1.264,00€1mL*10mM (DMSO)274,00€Borussertib
CAS:Borussertib is a covalent-allosteric and first-in-class inhibitor of protein kinase Akt(IC50 of 0.8 nM and a Ki of 2.2 nM for Aktwt)Fórmula:C36H32N6O3Pureza:99.00%Forma y color:SolidPeso molecular:596.68Ref: TM-T8427
1mg133,00€5mg274,00€10mg432,00€25mg715,00€50mg1.008,00€100mg1.359,00€1mL*10mM (DMSO)360,00€FAK-IN-11
FAK-IN-11 (Compound 4l), a FAK inhibitor, specifically targets the ATP binding pocket of FAK to prevent its phosphorylation.Fórmula:C25H41NO3Pureza:98%Forma y color:SolidPeso molecular:403.6Tirbanibulin Mesylate
CAS:Tirbanibulin Mesylate (KX01 Mesylate) is an inhibitor of Src that targets the peptide substrate site of Src (GI50: 9-60 nM in cancer cell lines).Fórmula:C27H33N3O6SPureza:99.42%Forma y color:SolidPeso molecular:527.63Ref: TM-T15675
2mg38,00€5mg56,00€10mg70,00€25mg126,00€50mg243,00€100mg416,00€200mg562,00€1mL*10mM (DMSO)65,00€IPI-493
CAS:IPI-493 is a bioactive chemical.Fórmula:C28H39N3O8Pureza:100%Forma y color:SolidPeso molecular:545.62WAY-118959-A
CAS:WAY-118959-A is a potential microtubule acetylation inhibitor.Fórmula:C16H14N4OS2Pureza:99.86%Forma y color:SolidPeso molecular:342.44Ref: TM-T60065
1mg115,00€5mg255,00€10mg375,00€25mg562,00€50mg787,00€100mg1.074,00€200mg1.454,00€1mL*10mM (DMSO)261,00€Sangivamycin
CAS:Sangivamycin (NSC-65346) inhibits PKC (Ki=10μM) and hinders growth in various human cancers.Fórmula:C12H15N5O5Pureza:98.11%Forma y color:SolidPeso molecular:309.28Ref: TM-T9605
1mg126,00€5mg274,00€10mg416,00€25mg677,00€50mg944,00€100mg1.264,00€1mL*10mM (DMSO)360,00€AKT-IN-2
CAS:AKT-IN-2 is a selective, and orally bioavailable AKT inhibitor (IC50: 5 nM for AKT1).Fórmula:C25H34F3N7OPureza:98%Forma y color:SolidPeso molecular:505.583CAI
CAS:3CAI inhibits AKT1/2, reduces mTOR/GSK3β, and triggers apoptosis in colon cancer cells.Fórmula:C10H8ClNOPureza:98.13%Forma y color:SolidPeso molecular:193.63Ref: TM-T14034
5mg55,00€10mg77,00€25mg125,00€50mg220,00€100mg330,00€200mg485,00€500mg787,00€1mL*10mM (DMSO)64,00€