Señalización citoesquelética
Los inhibidores de la señalización del citoesqueleto son compuestos que interrumpen las vías de señalización que regulan el citoesqueleto, crucial para la forma celular, la motilidad, la división y el transporte intracelular. Estos inhibidores se utilizan para estudiar la dinámica de las proteínas del citoesqueleto, como la actina y la tubulina, y su papel en procesos como la migración celular, la adhesión y la metástasis del cáncer. Los inhibidores de la señalización del citoesqueleto son valiosos en la investigación sobre biología celular, cáncer y neurobiología. En CymitQuimica, ofrecemos una amplia gama de inhibidores de la señalización del citoesqueleto de alta calidad para apoyar su investigación en estas áreas.
Productos de "Señalización citoesquelética"
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ILK-IN-3
CAS:ILK-IN-3 is an inhibitor of integrin linked kinase, and with antitumor activity.Fórmula:C10H12N6OPureza:99.69%Forma y color:SolidPeso molecular:232.24(±)-1,2-Diolein
CAS:(±)-1,2-Diolein (1,2-Dioleoyl-rac-glycerol) (1,2-Dioleoyl-rac-glycerol) is a PKC activator. (±)-1,2-Diolein could increases myotubes Ca 2+ influx.Fórmula:C39H72O5Forma y color:SolidPeso molecular:620.99Alvespimycin
CAS:Alvespimycin (17-DMAG) is a potent Hsp90 inhibitor with potential anticancer activity, which acts by binding to Hsp90.Fórmula:C32H48N4O8Pureza:100%Forma y color:SolidPeso molecular:616.75IIQLPEIVVV TFA
IIQLPEIVVV TFA serves as a specific inhibitor targeting the Drp1-Mff interaction. This compound discriminates between physiological and pathological fission, hindering physiological fission which leads to mitochondrial dysfunction. IIQLPEIVVV TFA is also utilized in research related to Huntington's disease.Fórmula:C54H95N11O14·xC2HF3O2Forma y color:SolidPeso molecular:1122.40 (free base)Tyrosine kinase-IN-9
CAS:Tyrosine kinase-IN-9 (Compound B) is an inhibitor of c-Abl. It is useful for studying neurodegenerative diseases, such as Alzheimer's disease and Parkinson's disease.Fórmula:C20H14ClN3O3Forma y color:SolidPeso molecular:379.796PF-03814735
CAS:PF-03814735 is a novel, potent and reversible inhibitor of Aurora A/B with IC50of 0.8 nM/5 nM, is less potent to Flt3, FAK, TrkA, and minimally active to Met and FGFR1. Phase 1.Fórmula:C23H25F3N6O2Pureza:98%Forma y color:SolidPeso molecular:474.48Tirofiban
CAS:Tirofiban (L700462) (MK-383) is a selective palate GPIIb/IIIa antagonist which inhibits platelet aggregation with IC50 of 9 nM.Fórmula:C22H36N2O5SPureza:99.87%Forma y color:SolidPeso molecular:440.63-Hydroxyxanthone
CAS:3-Hydroxyxanthone (3-Hydroxy-xanthen-9-one), a xanthone derivative, exhibits inhibitory effects on NADPH-catalyzed lipid peroxidation in human umbilical veinFórmula:C13H8O3Pureza:98%Forma y color:SolidPeso molecular:212.2NPX800
CAS:NPX800 is an inhibitor of heat shock factor 1 (HSF1) and can be used in studies about the treatment of cancer.Fórmula:C32H32FN5O4Pureza:99.26%Forma y color:SolidPeso molecular:569.63Ref: TM-T9804
1mg96,00€5mg240,00€10mg375,00€25mg627,00€50mg893,00€100mg1.216,00€1mL*10mM (DMSO)300,00€AKT-IN-6
CAS:AKT-IN-6 (INCB-047775) inhibits Akt, a key signaling protein linked to type 2 diabetes and cancer.Fórmula:C22H20FN5OPureza:98.83%Forma y color:SolidPeso molecular:389.43Ref: TM-T36310
1mg35,00€5mg74,00€10mg111,00€25mg216,00€50mg354,00€100mg567,00€200mg805,00€1mL*10mM (DMSO)84,00€Radicicol
CAS:Radicicol is an antifungal antibiotic, a inhibitor of Hsp90 & FTO, Anti-malarial , inhibits iNOS gene expression by blocking the p38 kinase and NF-κB/Rel.Fórmula:C18H17ClO6Pureza:98%Forma y color:White/Yellow PowderPeso molecular:364.78Phorbol 12-myristate 13-acetate
CAS:Phorbol 12-myristate 13-acetate (PMA) belongs to the phorbol ester group of natural products and is an activator of PKC, SphK, and NF-κB.Fórmula:C36H56O8Pureza:100% - 99.5%Forma y color:White To Off-White SolidPeso molecular:616.83Eg5 Inhibitor V, trans-24
CAS:Eg5 Inhibitor V, trans-24 is a specific and potent Eg5 inhibitor that can be used in cancer research with an IC50 value of 0.65 uM.Fórmula:C26H21N3O3Pureza:97.45%Forma y color:SolidPeso molecular:423.46Ref: TM-T11155
1mg92,00€5mg205,00€10mg305,00€25mg495,00€50mg677,00€100mg905,00€200mg1.216,00€1mL*10mM (DMSO)227,00€A-286982
CAS:A 286982 blocks the LFA-1 and ICAM-1 integrin-ligand interaction.Fórmula:C24H27N3O4SPureza:97.81%Forma y color:SolidPeso molecular:453.55Ref: TM-T21781
1mg35,00€2mg50,00€5mg74,00€10mg107,00€25mg210,00€50mg350,00€100mg522,00€1mL*10mM (DMSO)81,00€BX517
CAS:BX517 (PDK1 inhibitor 2) is a potent and selective inhibitor of PDK1.Fórmula:C15H14N4O2Pureza:99.07%Forma y color:SolidPeso molecular:282.3DTHIB
CAS:DTHIB robustly inhibits the HSF1 cancer gene signature and prostate cancer cell proliferation.Fórmula:C13H9ClFN3O3Pureza:98.86% - 99.29%Forma y color:SolidPeso molecular:309.68Ref: TM-T8858
1mg35,00€5mg70,00€10mg104,00€25mg210,00€50mg338,00€100mg540,00€500mg1.130,00€1mL*10mM (DMSO)78,00€AN-019
CAS:AN-019 (NRC-019) is a Bcr-Abl kinase inhibitor with antitumor activity for the study of chronic myelogenous leukemia (CML) and breast cancer.Fórmula:C25H17F6N5OPureza:98.01%Forma y color:SolidPeso molecular:517.43ZIP acetate(863987-12-6 free base)
ZIP acetate inhibits PKMζ (protein kinase Mζ), affecting LTP maintenance and spatial memory, with an IC50 of 1-2.5 μM.Fórmula:C92H158N30O19Pureza:94.68%Forma y color:SolidPeso molecular:1988.43Tilavonemab
CAS:Tilavonemab (ABBV-8E12), a humanized anti-tau antibody, halts tau uptake in neurons and may help with Alzheimer's research.Pureza:95% - 95%Forma y color:LiquidSuprafenacine
CAS:Suprafenacine (N'-[(E)-(4-methylphenyl)methylidene]-4,5,6,7-tetrahydro-1H-indazole-3-carbohydrazide) is a cell-permeable microtubule destabilizer that inducesFórmula:C16H18N4OPureza:99.72%Forma y color:SolidPeso molecular:282.34
