TNF
TNF (Tumor Necrosis Factor) inhibitors are compounds that block the activity of TNF, a cytokine involved in inflammation and the regulation of apoptosis. TNF can induce apoptosis in some cell types while promoting survival and inflammation in others. Inhibiting TNF is crucial in the treatment of autoimmune diseases, chronic inflammatory conditions, and certain cancers. TNF inhibitors help to modulate the immune response and reduce tissue damage caused by excessive inflammation. At CymitQuimica, we provide a diverse range of high-quality TNF inhibitors to support your research in immunology, inflammation, and apoptosis.
Products of "TNF"
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Dacetuzumab
CAS:Dacetuzumab (SGN 40) is a humanized anti-CD40 monoclonal antibody with antitumor activity for the study of recurrent diffuse large B-cell lymphoma.Purity:95% - 95%Color and Shape:LiquidMitazalimab
CAS:Mitazalimab (ADC-1013/JNJ-64457107) is a CD40 agonist that stimulates T cells to attack tumors and remodels the tumor microenvironment.Purity:95% - 95%Color and Shape:LiquidGNE684
CAS:GNE684 inhibits RIP1; Ki app: 21 nM (human), 189 nM (mouse), 691 nM (rat).Formula:C23H24N6O3Purity:98%Color and Shape:SolidMolecular weight:432.48Ragifilimab
CAS:Ragifilimab (INCAGN-1876), a GITR-targeting agonist antibody, may treat advanced solid tumors.Purity:SDS-PAGE:95% SEC-HPLC:99.99%Color and Shape:LiquidMolecular weight:146.46 kDaPK68
CAS:PK68 selectively inhibits RIPK1 (IC50=90nM), potentially useful in inflammation and cancer metastasis studies.Formula:C22H24N4O3SPurity:98.09% - 98.13%Color and Shape:SolidMolecular weight:424.52Ref: TM-T12493
1mg86.00€5mg170.00€10mg274.00€25mg520.00€50mg750.00€100mg1,026.00€200mg1,388.00€1mL*10mM (DMSO)188.00€CPI1189
CAS:CPI1189 (REN-1189) is a TNF-a release inhibitor potentially for the treatment of sciatica and postherpetic neuralgia.Formula:C13H18N2O2Purity:98.87% - 99.68%Color and Shape:SolidMolecular weight:234.291-(4-chloro-3-(trifluoromethyl)phenyl)-3-(7-(1-methyl-1H-pyrazol-4-yl)-2,3,4,9-tetrahydro-1H-carbazol-3-yl)urea
CAS:1-(4-chloro-3-(trifluoromethyl)phenyl)-3-(7-(1-methyl-1H-pyrazol-4-yl)-2,3,4,9-tetrahydro-1H-carbazol-3-yl)urea 是一种能够激动 TNF-α的化合物,可以诱导细胞分泌 TNF-α。Formula:C24H21ClF3N5OPurity:97.90% - 98.61%Color and Shape:SoildMolecular weight:487.9Sotigalimab
CAS:Sotigalimab (APX 005) is a monoclonal antibody targeting CD40 with anticancer activity for the study of metastatic pancreatic cancer.Purity:95% - 95%Color and Shape:LiquidEnavatuzumab
CAS:Enavatuzumab (PDL192) is a humanized monoclonal antibody targeting TWEAK receptor with anti-tumor activity.Purity:>95%Color and Shape:LiquidInfliximab
CAS:Infliximab is a chimeric monoclonal antibody that inhibits TNF-α. Infliximab can be used to treat Crohn's disease and rheumatoid arthritis. Cost-effective and quality-assured.Purity:98% - 99.70%Color and Shape:LiquidMolecular weight:149 kDaTNF α Protein, Human, Recombinant (aa 57-233, His)
TNF alpha Protein, Human, Recombinant (aa 57-233, His) is expressed in E.Color and Shape:Lyophilized PowderMolecular weight:18 KDa (reducing condition)Roquinimex
CAS:Roquinimex (FCF89) (Linomide) is a quinoline derivative immunostimulant which increases NK cell activity and macrophage cytotoxicity; inhibits angiogenesis andFormula:C18H16N2O3Purity:97.69%Color and Shape:SolidMolecular weight:308.33Ref: TM-T4412
2mg44.00€5mg65.00€10mg96.00€25mg167.00€50mg283.00€100mg454.00€200mg648.00€1mL*10mM (DMSO)72.00€TNF-α-IN-1
CAS:TNF-α-IN-1 is a TNF-α inhibitor.Formula:C16H14ClN3O5Purity:98%Color and Shape:SolidMolecular weight:363.75Resatorvid
CAS:Resatorvid (TAK-242) inhibits TLR4, with IC50s for IL-6, TNF-R, NO at 1.3, 1.9, 1.8 nM respectively.Formula:C15H17ClFNO4SPurity:100% - 99.9%Color and Shape:SolidMolecular weight:361.82Ref: TM-TQ0181
1mg49.00€2mg70.00€5mg96.00€10mg164.00€25mg306.00€50mg502.00€100mg805.00€1mL*10mM (DMSO)116.00€L6H21
CAS:L6H21 is an MD-2 inhibitor that can be used to study cognitive impairment and brain damage.Formula:C18H18O4Purity:99.26%Color and Shape:SolidMolecular weight:298.33VU0285655-1
CAS:VU0285655-1, a PLD2 inhibitor, halts PLD2-deficient cell growth and protects against high glucose-induced cell death. Used in diabetic retinopathy research.Formula:C25H27N5O2Purity:99.73%Color and Shape:SolidMolecular weight:429.51TNF α Protein, Ferret, Recombinant (His)
TNF alpha Protein, Ferret, Recombinant (His) is expressed in E.Color and Shape:Lyophilized PowderMolecular weight:18.88 kDa (predicted) same as Tris-Bis PAGE result.TNF α Protein, Human, Recombinant (aa 77-233, His)
TNF alpha Protein, Human, Recombinant (aa 77-233, His) is expressed in E.Purity:Greater than 95% as determined by reducing SDS-PAGE - SDS-PAGE: 99.66%; SEC-HPLC: 96.3%Color and Shape:Lyophilized PowderMolecular weight:16 KDa (reducing condition)Hernandezine
CAS:Hernandezine is an activator of AMPK activator and a selective reversing agent for ABCB1-mediated MDR in cancer cells.Formula:C39H44N2O7Purity:99.53%Color and Shape:SolidMolecular weight:652.78Kdo2-Lipid A ammonium
CAS:Kdo2-Lipid A ammonium (KLA) is a selective and potent TLR4 agonist, a lipopolysaccharide.Kdo2-Lipid A ammonium induces the release of TNF and PGE2.Formula:C110H214N6O39P2Purity:98%Color and Shape:SolidMolecular weight:2306.84
