TNF
TNF (Tumor Necrosis Factor) inhibitors are compounds that block the activity of TNF, a cytokine involved in inflammation and the regulation of apoptosis. TNF can induce apoptosis in some cell types while promoting survival and inflammation in others. Inhibiting TNF is crucial in the treatment of autoimmune diseases, chronic inflammatory conditions, and certain cancers. TNF inhibitors help to modulate the immune response and reduce tissue damage caused by excessive inflammation. At CymitQuimica, we provide a diverse range of high-quality TNF inhibitors to support your research in immunology, inflammation, and apoptosis.
Products of "TNF"
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Lucatumumab
CAS:Lucatumumab (HCD122) is a fully human anti-CD40 monoclonal antibody with anti-tumor activity for the study of multiple myeloma.Purity:95% - 95%Color and Shape:LiquidTNF α Protein, Cynomolgus, Recombinant (His)
TNF alpha Protein, Cynomolgus, Recombinant (His) is expressed in HEK293 mammalian cells with N-His tag.Color and Shape:Lyophilized PowderMolecular weight:18.35 kDa (predicted). Due to glycosylation, the protein migrates to 19-25 kDa based on Tris-Bis PAGE result.Utomilumab
CAS:Utomilumab, a humanized IgG2 against T-cell receptor 4-1BB/CD137, shows antitumor effects in advanced cancers.Formula:C17H24N8O3Purity:SDS-PAGE:95.2%;SEC-HPLC:98.5%Color and Shape:LiquidMolecular weight:142.77 kDacRIPGBM
CAS:cRIPGBM induces apoptosis in GBM CSCs by targeting RIPK2, with an EC50 of 68 nM in GBM-1 cells.Formula:C26H20FN2O2Purity:98%Color and Shape:SolidMolecular weight:411.45Homovanillyl alcohol
CAS:Homovanillyl alcohol is a biological metabolite of Hydroxytyrosol.Formula:C9H12O3Purity:99.62%Color and Shape:Cream To Light Brown ChunksMolecular weight:168.19Brentuximab
CAS:Brentuximab is a chimeric antibody targeting CD30 and is a naked antibody to Brentuximab vedotin.Brentuximab has antitumor activity and may be used to studyPurity:95% - 97.1% (SEC-HPLC)Color and Shape:LiquidMolecular weight:145.21 kDaGiloralimab
CAS:Giloralimab (ABBV-927) is a antibody targeting CD40 with anticancer activity for the study of triple-negative breast cancer and non-small cell lung cancer.Purity:95% - 95%Color and Shape:LiquidTigatuzumab
CAS:Tigatuzumab (CS-1008) is a humanized monoclonal antibody targeting DR5 and is a TRAIL-R2 agonist with antitumor activity that induces apoptosis in cancer cells.Purity:95% - 95%Color and Shape:LiquidMolecular weight:144.6 (kDa)HOMOPLANTAGININ
CAS:Homoplantaginin is a flavonoid from a traditional Chinese medicine Salvia plebeia,it has a protective and therapeutic effect on hepatocyte injury and showsFormula:C22H22O11Purity:97.63% - 99.66%Color and Shape:SolidMolecular weight:462.4Ref: TM-T4S0217
5mg50.00€10mg74.00€25mg140.00€50mg226.00€100mg324.00€200mg464.00€1mL*10mM (DMSO)52.00€IA-14069
CAS:IA-14069 is a TNF-a inhibitor with anti-inflammatory activity and pro-inflammatory cytokine production, and is used in the study of colon cancer.Formula:C20H15ClF2O4Color and Shape:SoildMolecular weight:392.78R-7050
CAS:R-7050 (TNF-α Antagonist III), a tumor necrosis factor receptor (TNFR) antagonist, exhibits heightened selectivity for TNFα.Formula:C16H8ClF3N4SPurity:98.64%Color and Shape:SolidMolecular weight:380.77Ref: TM-T4637
2mg46.00€5mg66.00€10mg96.00€25mg207.00€50mg283.00€100mg464.00€500mg1,008.00€1mL*10mM (DMSO)74.00€Cot inhibitor-1 hydrochloride
Cot inhibitor-1 hydrochloride blocks TPL-2 kinase (IC50=28nM) and TNF-α synthesis (IC50=5.7nM) in human blood.Formula:C27H28Cl3FN8Purity:98.26%Color and Shape:SoildMolecular weight:589.92Ref: TM-T10865L
1mg125.00€5mg240.00€10mg379.00€25mg632.00€50mg899.00€100mg1,216.00€1mL*10mM (DMSO)283.00€Drozitumab
CAS:Drozitumab (PRO 95780) is a fully humanized antibody targeting the death receptor DR5 for the study of triple-negative breast cancer.Purity:95% - 95%Color and Shape:LiquidMolecular weight:143.1 (kDa)Iscalimab
CAS:Iscalimab (CFZ-533) is a humanized monoclonal antibody targeting CD40, used in research on myasthenia gravis and Sjögren’s syndrome.Purity:>95%Color and Shape:LiquidTNF α Protein, Rabbit, Recombinant
Tumor necrosis factor alpha (TNFα) is the prototypic ligand of the TNF superfamily.Purity:98% - > 99.9%Color and Shape:Lyophilized PowderMolecular weight:18 KDa (reducing condition)Prim-O-glucosylcimifugin
CAS:Prim-O-glucosylcimifugin (Cimifugin 7-glucoside) can inhibit the proliferation of SMC stimulated by TNF-alpha, increase the proportion of G0/G1 phase.Formula:C22H28O11Purity:98.57% - 99.92%Color and Shape:SolidMolecular weight:468.45Cetrelimab
CAS:Cetrelimab (JNJ 63723283) is a humanized monoclonal antibody targeting PD-1, useful in research on multiple myeloma and bladder cancer.Purity:>95%Color and Shape:LiquidTulisokibart
CAS:Tulisokibart (PRA023) is a humanized anti-TNFSF15 monoclonal antibody used to study colon cancer.Color and Shape:LiquidAnti-Mouse TNF α Antibody (TN3-19.12)
Anti-Mouse TNF alpha Antibody is a rat-derived IgG inhibitor targeting mouse TNF alpha.Purity:95% - ＞10mg/mlColor and Shape:Odour LiquidGolimumab
CAS:Golimumab (CNTO-148), an anti-TNFα IgG1κ monoclonal antibody with anti-inflammatory and anti-cancer activity, can be used to prevent inflammation and cartilage.Color and Shape:LiquidMolecular weight:146.93 kDa
