TNF
TNF (Tumor Necrosis Factor) inhibitors are compounds that block the activity of TNF, a cytokine involved in inflammation and the regulation of apoptosis. TNF can induce apoptosis in some cell types while promoting survival and inflammation in others. Inhibiting TNF is crucial in the treatment of autoimmune diseases, chronic inflammatory conditions, and certain cancers. TNF inhibitors help to modulate the immune response and reduce tissue damage caused by excessive inflammation. At CymitQuimica, we provide a diverse range of high-quality TNF inhibitors to support your research in immunology, inflammation, and apoptosis.
Products of "TNF"
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Conatumumab
CAS:Conatumumab (AMG 655) targets DR5 to induce apoptosis in tumors, with Kd of 1 nM (long DR5) and 0.8 nM (short DR5).Purity:> 95% - > 95%Color and Shape:LiquidMolecular weight:145 kDa (average)Linarin
CAS:Linarin inhibits acetylcholinesterase, reduces liver injury via TNF-α, protects neurons via PI3K/Akt, and has enhanced absorption with piperine.Formula:C28H32O14Purity:97.95% - 98.99%Color and Shape:White To Off White PowderMolecular weight:592.557,3',4'-Tri-O-methylluteolin
CAS:7,3',4'-Tri-O-methylluteolin is anti-inflammatory, antibacterial, antifungal, and has moderate antitrypanosomal effects (MIC 19.0 ug/ml).Formula:C18H16O6Purity:98.66% - 98.99%Color and Shape:SolidMolecular weight:328.32Ref: TM-TN1291
1mg87.00€5mg170.00€10mg264.00€25mg452.00€50mg647.00€100mg900.00€1mL*10mM (DMSO)187.00€Ozoralizumab
CAS:Ozoralizumab (ATN-103) is a humanized anti-TNFα antibody and a novel TNFα inhibitor.Purity:SDS-PAGE:> 95%;SEC-HPLC:95.6%Color and Shape:LiquidMolecular weight:38.44 kDaSTING-IN-2
CAS:STING-IN-2 (C-170) is a potent and covalent inhibitor of STING. STING-IN-2 can be used for autoinflammatory disease research.Formula:C15H16N2O4Purity:98.61%Color and Shape:SolidMolecular weight:288.3TNF α Protein, Human, Recombinant (His & Avi)
TNF alpha Protein, Human, Recombinant (His & Avi) is expressed in HEK293 mammalian cells with C-His-Avi tag.Color and Shape:Lyophilized PowderMolecular weight:20.3 kDa (predicted). Due to glycosylation, the protein migrates to 21-25 kDa based on Tris-Bis PAGE result.(Rac)-Benpyrine
CAS:(Rac)-Benpyrine is a potent and orally active inhibitor of TNF-α.Formula:C16H16N6OPurity:98.44%Color and Shape:SolidMolecular weight:308.34Ref: TM-T8692
1mg73.00€5mg124.00€10mg187.00€25mg376.00€50mg562.00€100mg802.00€500mg1,644.00€1mL*10mM (DMSO)137.00€Clematichinenoside AR
CAS:Clematichinenoside AR is anti-inflammatory, immunosuppressive, and combats arthritis via PI3K/Akt and TNF-α pathways.Formula:C82H134O43Purity:99.49% - 99.69%Color and Shape:SolidMolecular weight:1807.92GSK2593074A
CAS:GSK2593074A (GSK'074) is a programmed necrosis inhibitor that displays inhibitory effects on RIP1 and RIP3.Formula:C27H23N5OSPurity:100%Color and Shape:SolidMolecular weight:465.57Ref: TM-T11484
1mg114.00€5mg274.00€10mg432.00€25mg725.00€50mg1,017.00€100mg1,359.00€1mL*10mM (DMSO)303.00€Selicrelumab
CAS:Selicrelumab (RG-7876) is an antibody targeting CD40 with potential anti-tumor activity for the study of pancreatic cancer.Purity:95% - 95%Color and Shape:LiquidAdalimumab
CAS:Adalimumab (anti-TNF-alpha) is the first fully human recombinant IgG1 monoclonal antibody that specifically targets human TNF-alpha.Purity:95% - 99.50%Color and Shape:LiquidMolecular weight:145.4 kDaNodinitib-1
CAS:Nodinitib-1 (CID-1088438) is a potent and selective NOD1 inhibitor with an IC50 of 0.56 μM.Formula:C14H13N3O2SPurity:99.97% - 99.98%Color and Shape:SolidMolecular weight:287.34TNF-α-IN-9
CAS:TNF-α-IN-9 is an NDM-1 inhibitor-3 analog and is a TNF-α inhibitor.TNF-α-IN-9 shows low inhibitory activity.Formula:C17H14O4Purity:98.28%Color and Shape:SoildMolecular weight:282.29Teneliximab
CAS:Teneliximab (BMS 224819) is a chimeric monoclonal antibody that blocks CD40-CD40L interactions.Cost-effective and quality-assured.Purity:95.00% - 99.19% (SEC-HPLC)Color and Shape:LiquidMolecular weight:146.06 kDaAstilbin
CAS:Astilbin (Neoastilbin) is actions Flavonoid phytochemical found in St. John′s wort and Traditional Chinese Medicine herbal preparations.Formula:C21H22O11Purity:97% - 99.76%Color and Shape:White PowderMolecular weight:450.39Ref: TM-T2794
5mg52.00€10mg77.00€25mg140.00€50mg224.00€100mg334.00€200mg477.00€500mg778.00€1mL*10mM (DMSO)51.00€Sinensetin
CAS:Sinensetin, a citrus flavone, has antiangiogenic, anti-inflammatory properties, and promotes fat formation and breakdown.Formula:C20H20O7Purity:97.74% - 99.33%Color and Shape:Pale Creamy Yellow PowderMolecular weight:372.37Zigakibart
CAS:Zigakibart (BION-1301) is a humanized monoclonal antibody targeting TNFSF13 with anti-inflammatory activity for the study of immunoglobulin A nephropathy (IgAN)Color and Shape:LiquidSciadopitysin
CAS:Sciadopitysin may thwart diabetic bone disease, boost mitochondria, protect osteoblasts, and hinder Aβ aggregation/neurotoxicity.Formula:C33H24O10Purity:98.14% - 99.17%Color and Shape:SolidMolecular weight:580.54Ref: TM-T5S2129
1mg52.00€5mg95.00€10mg162.00€25mg304.00€50mg455.00€100mg653.00€500mg1,349.00€1mL*10mM (DMSO)130.00€UTL-5g
CAS:UTL-5g is a chemoprotective TNF-α inhibitor reducing cisplatin side effects and toxicity in liver, kidneys, and blood.Formula:C11H8Cl2N2O2Purity:99.83%Color and Shape:SolidMolecular weight:271.1Ref: TM-T8845
1mg50.00€5mg105.00€10mg164.00€25mg321.00€50mg452.00€100mg645.00€200mg868.00€1mL*10mM (DMSO)129.00€CDC801
CAS:CDC801 is an inhibitor of PDE4 and TNF-α with IC50s of 1.1 μM and 2.5 μM, respectively.Formula:C23H24N2O5Purity:98.81%Color and Shape:SolidMolecular weight:408.45
