Caspase
Caspase inhibitors are compounds that block the activity of caspases, a family of proteases that are central executors of apoptosis. Caspases cleave specific substrates within the cell to trigger the apoptotic process, leading to programmed cell death. Caspase inhibitors are used to study the mechanisms of apoptosis, as well as to prevent unwanted cell death in various research models. These inhibitors are also explored in therapeutic contexts to protect cells from apoptosis in diseases such as neurodegeneration. At CymitQuimica, we offer a wide range of high-quality caspase inhibitors to support your research in apoptosis, cell death, and related fields.
Products of "Caspase"
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PQ401
CAS:PQ401 (IGF-1R Inhibitor II) suppresses autophosphorylation of IGF-1R domain(IC50<1 μM).Formula:C18H16ClN3O2Purity:99.13%Color and Shape:SolidMolecular weight:341.79Penicillic acid
CAS:Penicillic acid, a mycotoxin from Aspergillus/Penicillium, blocks Fas ligand apoptosis and is cytotoxic to rat lung macrophages.Formula:C8H10O4Purity:98%Color and Shape:Needles From Petroleum Ether Slight Yellow PowderMolecular weight:170.16Brazilein
CAS:Brazilein, a natural antioxidant, inhibits adipocyte differentiation by inhibiting PPAR γ induction, inhibits skin cancer cells through increasing caspase-3 .Formula:C16H12O5Color and Shape:SolidMolecular weight:284.26Taurodeoxycholic acid sodium hydrate
CAS:Taurodeoxycholic acid sodium hydrate (Sodium taurodeoxycholate monohydrate), a hydrophilic bile salt, on bile salt and biliary lipid secretion in the rat.Formula:C26H46NNaO7SPurity:98.87%Color and Shape:SolidMolecular weight:539.70Crustecdysone
CAS:Crustecdysone (Hydroxyecdysone) is a steroid hormone that regulates the processes of molting or ecdysis in insects.Formula:C27H44O7Purity:96.31% - 99.06%Color and Shape:Canary Yellow Fine PowderMolecular weight:480.63Raptinal
CAS:Raptinal activates caspase-3 directly and initiates intrinsic caspase-dependent apoptosis pathway in multiple cell lines.Formula:C28H18O2Purity:≥98%Color and Shape:SolidMolecular weight:386.44Ref: TM-T38563
1mg40.00€5mg88.00€10mg113.00€25mg180.00€50mg265.00€100mg393.00€200mg585.00€1mL*10mM (DMSO)87.00€PAC-1
CAS:PAC-1 (Procaspase activating compound 1) has been used in trials studying the treatment of Lymphoma, Melanoma, Solid Tumors, Breast Cancer and Thoracic Cancers.Formula:C23H28N4O2Purity:96.78% - 99.77%Color and Shape:SolidMolecular weight:392.49J22352
CAS:J22352, a PROTAC (proteolysis-targeting chimeras)-like and highly selective HDAC6 inhibitor with an IC50 value of 4.7 nM, enhances anticancer effects inFormula:C24H21N3O4Color and Shape:SolidMolecular weight:415.44Caspase-3-IN-2
CAS:Caspase-3-IN-2 (Compound 4d) acts as an inhibitor of α-Chymotrypsin. It also exhibits inhibitory activity against HIV protease and caspase 3, with inhibition rates of 57% and 51% respectively at a concentration of 100 μM.Formula:C10H6ClNO5Color and Shape:SolidMolecular weight:255.6115,7,4'-Trimethoxyflavone
CAS:5,7,4'-Trimethoxyflavone (4',5,7-Trimethoxyflavone) is isolated from Kaempferia parviflora (KP) which is a medicinal plant from Thailand.Formula:C18H16O5Purity:97.53%Color and Shape:SolidMolecular weight:312.32Tauroursodeoxycholate
CAS:Tauroursodeoxycholate (UR 906), a hydrophilic bile acid, low in humans, may treat PBC, insulin resistance, and ALS.Formula:C26H45NO6SPurity:98.12% - 99.93%Color and Shape:White SolidMolecular weight:499.7ZIF-8
CAS:ZIF-8 is an anticancer agent that can inherently trigger pyroptosis through a caspase-1/gasdermin D (GSDMD)-dependent pathway.Formula:C4H6N2ZnColor and Shape:SolidMolecular weight:147.5135,7-Dihydroxychromone
CAS:1.Formula:C9H6O4Purity:99.73% - ≥95%Color and Shape:SolidMolecular weight:178.14Ref: TM-T5S1805
1mg47.00€5mg88.00€10mg126.00€25mg208.00€50mg309.00€100mg462.00€500mg1,008.00€1mL*10mM (DMSO)80.00€Guggulsterone
CAS:Guggulsterone (Guggulsterone E&Z) E&Z is a 3-hydroxy steroid. It has a role as an androgen.Formula:C21H28O2Purity:99.40% - 99.8%Color and Shape:Light Yellow PowderMolecular weight:312.45Ref: TM-T5574
1mg35.00€5mg55.00€10mg93.00€25mg178.00€50mg245.00€100mg360.00€200mg532.00€1mL*10mM (DMSO)60.00€Oxidopamine hydrochloride
CAS:Oxidopamine hydrochloride (6-Hydroxydopamine hydrochloride) is an neurotransmitter dopamine antagonist.Formula:C8H12ClNO3Purity:96.17% - 99.85%Color and Shape:Physical Description Beige Solid (Ntp 1992)Molecular weight:205.64Belnacasan
CAS:Belnacasan (VX-765) is an orally active IL-converting enzyme/caspase-1 inhibitor.Formula:C24H33ClN4O6Purity:96.53% - 99.5%Color and Shape:SolidMolecular weight:508.99Ref: TM-T6090
2mg37.00€5mg50.00€10mg86.00€25mg170.00€50mg235.00€100mg419.00€200mg617.00€1mL*10mM (DMSO)56.00€CZL55
CAS:CZL55 is a potent caspase-1 inhibitor with an IC50 value of 0.024 μM.CZL55 has low cytotoxicity and can be used in the study of febrile seizures (FS).Formula:C20H22N2O6Purity:98.19%Color and Shape:SolidMolecular weight:386.4Z-LEVD-FMK
CAS:Z-LEVD-FMK is a caspase-4 inhibitor with anti-cancer activity, capable of eliminating LPS-induced GCLC protein degradation.Formula:C31H45FN4O10Color and Shape:SolidMolecular weight:652.71Lacidipine
CAS:Lacidipine (SN-305) is a slow-acting, long-duration lipophilic dihydropyridine calcium blocker that prevents reflex tachycardia and lowers blood pressure.Formula:C26H33NO6Purity:99.98%Color and Shape:White-To-Off-White Crystalline SolidMolecular weight:455.54Senkyunolide I
CAS:1. Senkyunolide I has neuroprotective effect, associated with its anti-oxidation and anti-apoptosis properties.Formula:C12H16O4Purity:99.73% - 99.88%Color and Shape:SolidMolecular weight:224.25Ref: TM-T5S2076
1mg48.00€5mg93.00€10mg123.00€25mg188.00€50mg283.00€100mg437.00€500mg938.00€1mL*10mM (DMSO)89.00€
