Caspase
Caspase inhibitors are compounds that block the activity of caspases, a family of proteases that are central executors of apoptosis. Caspases cleave specific substrates within the cell to trigger the apoptotic process, leading to programmed cell death. Caspase inhibitors are used to study the mechanisms of apoptosis, as well as to prevent unwanted cell death in various research models. These inhibitors are also explored in therapeutic contexts to protect cells from apoptosis in diseases such as neurodegeneration. At CymitQuimica, we offer a wide range of high-quality caspase inhibitors to support your research in apoptosis, cell death, and related fields.
Products of "Caspase"
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M826
M826, a non-peptide, potent, selective, and reversible caspase-3 inhibitor, exhibits an IC50 of 0.005 μM and demonstrates strong anti-apoptotic activity inFormula:C28H45N7O6Purity:98%Color and Shape:SolidMolecular weight:575.7PI-1840
CAS:PI-1840 is a reversible and selective chymotrypsin-like (CT-L) inhibitor, with little proteasome proteolytic effects on trypsin-like (T-L) and PGPH-L.Formula:C22H26N4O3Purity:98.82%Color and Shape:SolidMolecular weight:394.47Biotin-VAD-FMK
CAS:Biotin-VAD-FMK is a cell-permeable, irreversible biotin-labeled inhibitor of caspase. It is used to identify active caspases in cell lysates.Formula:C30H49FN6O8SColor and Shape:SolidMolecular weight:672.812-HBA
CAS:2-HBA, a synthetic analog of curcumin, is an indirect inducer of enzymes that catalyze detoxification reactions through the Keap1-Nrf2-ARE pathway.Formula:C17H14O3Purity:99.76%Color and Shape:SolidMolecular weight:266.29Ref: TM-T7374
2mg35.00€5mg52.00€10mg80.00€25mg144.00€50mg225.00€100mg359.00€200mg532.00€1mL*10mM (DMSO)58.00€Ref: TM-T5S2358
1mg57.00€2mg81.00€5mg111.00€10mg160.00€25mg263.00€50mg378.00€100mg558.00€200mg797.00€1mL*10mM (DMSO)123.00€Effusol
CAS:Effusol is a natural product, exhibits potent scavenging activity for DPPH and ABTS radicals(IC50 values of 79 μM and 2.73 μM, respectively).Formula:C17H16O2Purity:99.67%Color and Shape:SolidMolecular weight:252.31EF24
CAS:EF24 treatment boosts caspase 3/9 activity, hinders MEK1/ERK phosphorylation, and exhibits strong anti-tumor effects in OSCC by deactivating MAPK/ERK.Formula:C19H15F2NOPurity:98.47%Color and Shape:SolidMolecular weight:311.33Ref: TM-T27242
1g1,510.00€1mg40.00€5mg85.00€10mg133.00€25mg235.00€50mg354.00€100mg533.00€500mg1,130.00€1mL*10mM (DMSO)93.00€Sesamolin
CAS:Sesamolin and sesamin guard nerves, reduce microglia damage by blocking p38 MAPK and caspase-3, and curb nitric oxide in stimulated cells.Formula:C20H18O7Purity:98.77% - 99.04%Color and Shape:SolidMolecular weight:370.35Ref: TM-T5S2283
1mg40.00€5mg85.00€10mg135.00€25mg216.00€50mg324.00€100mg472.00€500mg1,026.00€1mL*10mM (DMSO)88.00€Paris saponin VII
CAS:Paris saponin VII (Dioscini) shows inhibitory effects on cell proliferation.Formula:C51H82O21Purity:99.51% - 99.63%Color and Shape:SolidMolecular weight:1031.18Dehydrotrametenolic acid
CAS:Dehydrotrametenolic acid (Dehydroeburicoic acid) induces necrotic cell death that involves Ca(2+) overload, mitochondrial dysfunction, and calpain activation inFormula:C31H48O3Purity:98%Color and Shape:SolidMolecular weight:468.71Aspirin
CAS:Aspirin (Acetylsalicylic Acid) is a COX inhibitor. Aspirin has anti-inflammatory, antipyretic and analgesic activities. Cost-effective and quality-assured.Formula:C9H8O4Purity:99.78% - 99.91%Color and Shape:White Solid CrystallineMolecular weight:180.16Tauroursodeoxycholate sodium
CAS:Tauroursodeoxycholate sodium (TUDC) is an endoplasmic reticulum (ER) stress inhibitor, used for the treatment of gallstones and liver cirrhosis.Formula:C26H44NNaO6SPurity:97.90%Color and Shape:SolidMolecular weight:521.69Fenbufen
CAS:Fenbufen (Lederfen) is a non-steroidal anti-inflammatory drug used primarily to treat inflammation in osteoarthritis, ankylosing spondylitis, and tendinitis.Formula:C16H14O3Purity:98.35% - 98.46%Color and Shape:White SolidMolecular weight:254.28AVN-944
CAS:AVN-944 (VX-944)(VX-944) is a selective, noncompetitive inhibitor of human IMPDH with Ki of 6-10 nM for IMPDH1/IMPDH2.Formula:C25H27N5O5Purity:99.07% - ≥95%Color and Shape:SolidMolecular weight:477.51δ-secretase inhibitor 11
CAS:δ-secretase inhibitor 11 is an inhibitor of δ-secretase and can be used as a lead compound for translational development of AD treatment.Formula:C10H12N4O2Purity:99.4%Color and Shape:SolidMolecular weight:220.23Ginsenoside Rh2
CAS:Ginsenoside Rh2 (20(S)-Ginsenoside Rh2), an extract of red Panax ginseng, is a potent anti-inflammatory and anticancer drug.Formula:C36H62O8Purity:99.20% - 99.76%Color and Shape:White PowderMolecular weight:622.87(Iso)-Z-VAD(OMe)-FMK
CAS:(Iso)-Z-VAD(OMe)-FMK is an isomer of Z-VAD(OMe)-FMK, which is a pan-caspase inhibitor with irreversible properties. Z-VAD(OMe)-FMK is also an inhibitor UCHL1.Formula:C22H30FN3O7Purity:97.10%Color and Shape:SoildMolecular weight:467.49BRD-810
BRD-810, a highly selective MCL1 inhibitor, binds to the MCL1 BH3 groove, impeding the sequestration of pro-apoptotic proteins and swiftly triggering caspase activation in MCL1-dependent cell lines. This compound exhibits anti-tumor efficacy in both blood cancer and solid tumor models.Formula:C39H44ClFN4O5Color and Shape:SolidMolecular weight:703.24Ossirene
CAS:Ossirene (AS101), a potent in vitro and in vivo immunomodulator, is a novel inhibitor of IL-1beta converting enzyme.Formula:C2H4Cl3O2Te·H4NPurity:≥95%Color and Shape:SolidMolecular weight:312.05Dehydrocorydaline chloride
CAS:Dehydrocorydaline chloride (13-Methylpalmatine chloride) is an alkaloid with anti-inflammatory and anti-cancer activity. Can improve the activation of p38 MAPK.Formula:C22H24ClNO4Purity:99.53%Color and Shape:SolidMolecular weight:401.88Ref: TM-T10990
1mg58.00€5mg111.00€10mg160.00€25mg264.00€50mg396.00€100mg563.00€1mL*10mM (DMSO)124.00€
