Caspase
Caspase inhibitors are compounds that block the activity of caspases, a family of proteases that are central executors of apoptosis. Caspases cleave specific substrates within the cell to trigger the apoptotic process, leading to programmed cell death. Caspase inhibitors are used to study the mechanisms of apoptosis, as well as to prevent unwanted cell death in various research models. These inhibitors are also explored in therapeutic contexts to protect cells from apoptosis in diseases such as neurodegeneration. At CymitQuimica, we offer a wide range of high-quality caspase inhibitors to support your research in apoptosis, cell death, and related fields.
Products of "Caspase"
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Sarglaroids F
Sarglaroids F (compound 6), an anti-inflammatory agent extracted from the roots of Grass Coral, suppresses LPS/ATP-induced IL-1β secretion by modulating K+Formula:C38H44O12Purity:98%Color and Shape:SolidMolecular weight:692.75Z-VAD(OMe)-FMK
CAS:View and buy Z-VAD(OMe)-FMK from TargetMol.Z-VAD(OMe)-FMK is a cell-permeable and irreversible pan-caspase inhibitor.Cited in 10 publications.Formula:C22H30FN3O7Purity:95.92% - 99.44%Color and Shape:SolidMolecular weight:467.49Ref: TM-T6013
1mg57.00€2mg88.00€5mg144.00€10mg235.00€25mg349.00€50mg472.00€100mg658.00€200mg933.00€1mL*10mM (DMSO)145.00€KEA1-97
CAS:Kea1-97 is a selective disruptor of interaction between thioredoxin and caspase-3 (IC50 = 10 μ M).Formula:C15H9Cl2FN4Purity:98.7%Color and Shape:SolidMolecular weight:335.16Q-VD-OPH
CAS:Q-VD-OPH (Quinoline-Val-Asp-Difluorophenoxymethylketone) is a pan-caspase inhibitor with potent antiapoptotic properties.Formula:C26H25F2N3O6Purity:97.8% - 98.95%Color and Shape:SolidMolecular weight:513.5Licochalcone A
CAS:Licochalcone A is a flavonoid isolated from the famous Chinese medicinal herb Glycyrrhiza uralensis Fisch with obvious anti-cancer effects.Formula:C21H22O4Purity:98.11% - 98.96%Color and Shape:White Crystalline PowderMolecular weight:338.4Dihydrocapsaicin
CAS:Dihydrocapsaicin, similar to capsaicin, is an irritant found in Capsicum, used in "pure" capsaicin products at about 10%, activates VR1, and is an antioxidant.Formula:C18H29NO3Purity:99.61% - ≥95%Color and Shape:White CrystalMolecular weight:307.43Z-FA-FMK
CAS:Z-FA-FMK can irreversibly inhibit cysteine protease and also inhibit effector caspases.Formula:C21H23FN2O4Purity:99.43% - 99.68%Color and Shape:SolidMolecular weight:386.42Ac-DEVD-CHO acetate
Caspase-3 Inhibitor I (N-acetyl-asp-glu-val-asp-al) is a specific inhibitor of Caspase-3.Formula:C22H34N4O13Purity:98.54%Color and Shape:SolidMolecular weight:562.52PHYTOSPHINGOSINE
CAS:Phytosphingosine: anticancer phospholipid; triggers apoptosis in cancer cells via caspase 8 activation and Bax translocation.Formula:C18H39NO3Purity:99.53%Color and Shape:SolidMolecular weight:317.51Z-VAD-FMK
CAS:Z-VAD-FMK (Caspase Inhibitor VI) is a broad-spectrum inhibitor of caspases.Z-VAD-FMK binds to activated caspases and inhibits apoptosis.Z-VAD-FMK does notFormula:C21H28FN3O7Purity:98.24% - 99.79%Color and Shape:SolidMolecular weight:453.46Ref: TM-T7020
1mg118.00€5mg245.00€10mg416.00€25mg662.00€50mg939.00€100mg1,264.00€200mg1,691.00€1mL*10mM (DMSO)269.00€Z-DEVD-FMK
CAS:Z-DEVD-FMK (Caspase-3 Inhibitor) is a selective, irreversible Caspase-3 inhibitor, and also exhibits effective inhibition activity on caspase-6, caspase-7,Formula:C30H41FN4O12Purity:96.19% - 99.69%Color and Shape:SolidMolecular weight:668.66Almorexant
CAS:Almorexant (ACT 078573), a strong dual orexin receptor antagonist, has Ki of 1.3 nM for OX1 and 0.17 nM for OX2.Formula:C29H31F3N2O3Purity:97.75% - 98.02%Color and Shape:SolidMolecular weight:512.56Ac-DEVD-AMC
CAS:Ac-DEVD-AMC (AC-ASP-MET-GLN-ASP-7-AMINO-4-METHYLCOUMARIN) is the substrate of Caspase-3 .Formula:C30H37N5O13Purity:98.20%Color and Shape:White PowderMolecular weight:675.6415-Acetoxyscirpenol
CAS:15-acetoxyscirpenol: ASM that induces apoptosis, inhibits Jurkat T cell growth dose-dependently, and activates caspases other than caspase-3.Formula:C17H24O6Purity:98%Color and Shape:SolidMolecular weight:324.373ZYZ-488
CAS:ZYZ-488 is an Apoptosis protease activating factor-1 (Apaf-1) inhibitor, which suppresses the activation of procaspase-9 and procaspase-3.Formula:C20H29N3O11Purity:99.04%Color and Shape:SolidMolecular weight:487.46Ac-VAD-CHO
CAS:Ac-Val-Ala-Asp-CHO (Ac-VAD-CHO) serves as a pan-caspase inhibitor and preserves mitochondrial membrane potential (MMP) while preventing the release ofFormula:C14H23N3O6Purity:98%Color and Shape:SolidMolecular weight:329.35Emricasan
CAS:Emricasan (IDN-6556) is a pan-caspase inhibitor with irreversible properties.Formula:C26H27F4N3O7Purity:98.13% - 99%Color and Shape:SolidMolecular weight:569.5Ref: TM-T6826
1mg44.00€2mg58.00€5mg95.00€10mg144.00€25mg254.00€50mg419.00€100mg617.00€1mL*10mM (DMSO)107.00€Duocarmycin A
CAS:Duocarmycin A: an antitumor DNA alkylator targeting adenine; induces apoptosis in HLC-2 cells.Formula:C26H25N3O8Purity:98%Color and Shape:SolidMolecular weight:507.49Z-YVAD-FMK
CAS:AA-Z-YVAD-FMK is a Irreversible caspase-1 inhibitor,with anti-inflammatory and anti-tumor activities.Formula:C31H39FN4O9Purity:98.00%Color and Shape:SolidMolecular weight:630.66Ac-VEID-AFC
Ac-VEID-AFC is a fluorogenic substrate for caspase-6, utilized in caspase-6 activity assays [1].Formula:C32H39F3N4O12Purity:98%Color and Shape:SolidMolecular weight:728.67
