Caspase
Caspase inhibitors are compounds that block the activity of caspases, a family of proteases that are central executors of apoptosis. Caspases cleave specific substrates within the cell to trigger the apoptotic process, leading to programmed cell death. Caspase inhibitors are used to study the mechanisms of apoptosis, as well as to prevent unwanted cell death in various research models. These inhibitors are also explored in therapeutic contexts to protect cells from apoptosis in diseases such as neurodegeneration. At CymitQuimica, we offer a wide range of high-quality caspase inhibitors to support your research in apoptosis, cell death, and related fields.
Products of "Caspase"
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Arnicolide D
CAS:Arnicolide D is a sesquiterpene lactone.Formula:C19H24O5Purity:96.66%Color and Shape:SolidMolecular weight:332.39Diclofenac Potassium
CAS:Diclofenac Potassium (CGP-45840B) is a nonsteroidal anti-inflammatory drug taken to reduce inflammation and as an analgesic reducing pain in certain conditions.Formula:C14H10Cl2KNO2Purity:99.51%Color and Shape:White To Yellowish Crystalline PowderMolecular weight:334.24Diclofenac diethylamine
CAS:Diclofenac Diethylamine, a non-selective COX inhibitor, is utilized as a nonsteroidal anti-inflammatory drug (NSAID).Formula:C18H22Cl2N2O2Purity:99.81% - 99.87%Color and Shape:SolidMolecular weight:369.29Z-IETD-FMK
CAS:Z-IETD-FMK (Z-IE(OMe)TD(OMe)-FMK) is a selective caspase 8 inhibitor, which has cell permeable.Formula:C30H43FN4O11Purity:95% - 99.81%Color and Shape:SolidMolecular weight:654.68Ref: TM-T7019
1mg125.00€2mg182.00€5mg263.00€10mg420.00€25mg682.00€50mgTo inquire1mL*10mM (DMSO)408.00€(2R,3S)-Emricasan
CAS:(2R,3S)-Emricasan ((2R,3S)-PF 03491390) is an isomer of Emricasan. This compound acts as an orally effective irreversible pan-caspase inhibitor. (2R,3S)-Emricasan inhibits the increase in caspase-3 activity induced by Zika virus (ZIKV) and protects human cortical neural progenitor cells.Formula:C26H27F4N3O7Color and Shape:SolidMolecular weight:569.5Boc-Asp(OMe)-fluoromethyl ketone
CAS:Boc-Asp(OMe)-FMK is a broad-spectrum caspase inhibitor that blocks Fas-mediated processes without affecting IL-8 chemotaxis.Formula:C11H18FNO5Purity:≥98%Color and Shape:SolidMolecular weight:263.26M190S
CAS:M109S is a novel small molecule that shields cells from mitochondria-dependent apoptosis, demonstrating effectiveness both in vitro and in vivo.Formula:C21H21N5O2Purity:98%Color and Shape:SolidMolecular weight:375.42Ivachtin
CAS:Ivachtin (Caspase-3 Inhibitor VII) is a nonpeptide, noncompetitive and reversibl caspase-3 inhibitor(IC50 = 23 nM) and is a modest inhibitor of the remainingFormula:C20H21N3O7SPurity:98.17%Color and Shape:SolidMolecular weight:447.46Anisperimus
CAS:Anisperimus (LF 15-0195) is an immunosuppressant that prevents CNS autoimmunity by promoting the development of regulatory CD4 T cells expressing Foxp3.Formula:C18H39N7O3Purity:98.10%Color and Shape:SolidMolecular weight:401.55ML-9
CAS:ML-9 suppresses MLCK, PKA, and PKC activity with Ki values of 4, 32, and 54 μM, respectively.Formula:C15H18Cl2N2O2SPurity:99.69%Color and Shape:Crystalline SolidMolecular weight:361.29Cystamine
CAS:Cystamine (2,2'-Disulfanediyldiethanamine) is an inhibitor of transglutaminase and inhibits caspase-3 with an IC50 value of 23.6 μM.Formula:C4H12N2S2Purity:99.41%Color and Shape:SolidMolecular weight:152.28Wedelolactone
CAS:Wedelolactone (IKK Inhibitor II) inhibits NF-κB-mediated gene transcription in cells by blocking the phosphorylation and degradation of IκBα.Formula:C16H10O7Purity:98.07% - 99.76%Color and Shape:SolidMolecular weight:314.25Ref: TM-T3384
1mg35.00€5mg74.00€10mg115.00€25mg185.00€50mg331.00€100mg437.00€500mg1,008.00€1mL*10mM (DMSO)52.00€Z-VEID-AFC
CAS:Z-VEID-AFC is a caspase-6 fluorescent substrate [1].Formula:C38H44F3N5O12Purity:98%Color and Shape:SolidMolecular weight:819.78TC11
CAS:TC11 (1H-Isoindole-1,3(2H)-dione, 5-amino-2-[2,6-bis(1-methylethyl)phenyl]-TC11) is a potent inhibitor of tumor cell proliferation and an inducer of apoptosisFormula:C20H22N2O2Purity:97.86%Color and Shape:SolidMolecular weight:322.4Oxidopamine hydrobromide
CAS:Oxidopamine hydrobromide (6-OHDA hydrobromide) is a neurotransmitter dopamine antagonist.Formula:C8H12BrNO3Purity:98.1% - 99.88%Color and Shape:Beige To Brown Fine Crystalline PowderMolecular weight:250.09Daphnetin
CAS:Daphnetin (7,8-Dihydroxycoumarin), a natural coumarin derivative, is a protein kinase inhibitor with inhibitory for EGFR (IC50: 7.67 μM), PKA (IC50: 9.33 μM),Formula:C9H6O4Purity:97.47% - 99.8%Color and Shape:SolidMolecular weight:178.14Aristolactam I
CAS:Aristolactam I (Aristololactum) has cytotoxic potency, mediated through the induction of apoptosis in a caspase 3-dependent pathway.Formula:C17H11NO4Purity:98.98% - 99.63%Color and Shape:SolidMolecular weight:293.27Ref: TM-T3S1227
1mg60.00€5mg140.00€10mg216.00€25mg369.00€50mg545.00€100mg775.00€1mL*10mM (DMSO)175.00€AKN-028
CAS:AKN-028 is an orally active and potent FLT3 tyrosine kinase inhibitor ( IC 50 = 6 nM). AKN-028 causes dose-dependent inhibition of FLT3 autophosphorylation.Formula:C17H14N6Purity:97.3%Color and Shape:SolidMolecular weight:302.33CIL62
CAS:CIL62 is a caspase-3/7-independent inducer of cell death. The mechanism of action of CIL62 is Necrostatin-1 dependent cell death [1].Formula:C23H26O5Purity:97.07%Color and Shape:SolidMolecular weight:382.45Ref: TM-T8468
1mg52.00€5mg116.00€10mg170.00€25mg335.00€50mg562.00€100mg758.00€200mg1,017.00€1mL*10mM (DMSO)128.00€
