Ferroptosis
Ferroptosis is a form of regulated cell death characterized by the accumulation of lipid peroxides and iron-dependent oxidative stress. Unlike apoptosis, ferroptosis is not driven by caspases but rather by the failure of cellular antioxidant defenses, leading to cell death. Ferroptosis inhibitors and inducers are critical for studying this unique cell death pathway, which is implicated in various diseases, including cancer, neurodegeneration, and ischemia-reperfusion injury. At CymitQuimica, we offer a wide range of high-quality ferroptosis modulators to support your research in cell death mechanisms, oxidative stress, and disease pathology.
Products of "Ferroptosis"
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L-Glutathione reduced
CAS:L-Glutathione reduced (Glutathione) is a naturally occurring tripeptide found in cells as an endogenous antioxidant that scavenges oxygen free radicals.Formula:C10H17N3O6SPurity:97.37% - 99.97%Color and Shape:SolidMolecular weight:307.32Tagitinin C
CAS:Tagitinin C is a sesquiterpene compound isolated from Tithonia diversifolia, an inducer of ferroptosis with anti-cancer activity.Formula:C19H24O6Color and Shape:SolidMolecular weight:348.39TBHQ
CAS:TBHQ (tert-Butylhydroquinone) is an antioxidant that induces an antioxidant response through the redox-sensitive transcription factor Nrf2.Formula:C10H14O2Purity:99.17% - 99.53%Color and Shape:White Solid PowderMolecular weight:166.22Cycloheximide
CAS:Cycloheximide (Naramycin A) is an antimitotic compound and an inhibitor of DNA and protein synthesis.Formula:C15H23NO4Purity:95.08% - 99.95%Color and Shape:SolidMolecular weight:281.35L-Glutamic Acid
CAS:Formula:C5H9NO4Purity:>99.0%(T)Color and Shape:White powder to crystalMolecular weight:147.13Ferroptosis-IN-3
Ferroptosis-IN-3 (Compound 25), a ferroptosis inhibitor, demonstrates potent activity by inhibiting RSL3-induced ferroptosis in HT-1080 cells (EC50: 8.6 nM).Purity:98%Color and Shape:Odour SolidTrigonelline
CAS:Trigonelline (Trigenolline), an alkaloid with potential antidiabetic activity, is present in considerable amounts in coffee.Formula:C7H7NO2Purity:98% - 99.49%Color and Shape:Prisms Aqueous From Alcohol + Water SolidMolecular weight:137.14GDCNF-11
CAS:GDCNF-11, an HSP90-based HIM-PROTACGPX4 degrader, facilitates the ubiquitination and degradation of GPX4 through the HSP90 chaperone complex. This reduction in endogenous GPX4 induces ferroptosis in HT-1080 cells, with a DC50 value of 0.08 μM.Formula:C48H53Cl2N13O5SColor and Shape:SolidMolecular weight:994.99CDDO-Im
CAS:CDDO-Im (TP-235) is an activator of Nrf2 and PPAR (Kis: 232/344 nM for PPARα/PPARγ).Formula:C34H43N3O3Purity:100% - 98.3%Color and Shape:SolidMolecular weight:541.72Ref: TM-TQ0120
1mg37.00€5mg79.00€10mg111.00€25mg210.00€50mg338.00€100mg512.00€500mg1,093.00€1mL*10mM (DMSO)94.00€Rosiglitazone
CAS:Rosiglitazone (BRL49653) is a PPARγ agonist, TRPC5 activator, and TRPM3 inhibitor with oral activity.Formula:C18H19N3O3SPurity:98.61% - 99.87%Color and Shape:White To Off-White Crystalline PowderMolecular weight:357.43Gallic acid
CAS:Gallic acid (Benzoic acid) is found in almost all plants. Plants known for their high gallic acid content include gallnuts,grapes,tea,hops and oak bark.Formula:C7H6O5Purity:99.57%Color and Shape:White Solid Solid Particulate/PowderMolecular weight:170.12Ciclopirox
CAS:Ciclopirox is an antifungal that chelates Fe3+ and Al3+, inhibiting enzymes and has antibacterial and anti-inflammatory effects.Formula:C12H17NO2Purity:97.72% - 99.41%Color and Shape:SolidMolecular weight:207.27FA16
FA16 is a selective, metabolically stable ferroptosis inducer with an IC50 value of 1.26 μM.FA16 is a derivative of 2-(trifluoromethyl)benzimidazole.FA16Formula:C22H27F3N4O2SPurity:99.75%Color and Shape:SolidMolecular weight:468.54Bay 11-7085
CAS:Bay 11-7085 can irreversibly inhibit the IκBα phosphorylation induced by TNFα (IC50: 10 μM).Formula:C13H15NO2SPurity:99.76% - 99.83%Color and Shape:White SolidMolecular weight:249.33Ref: TM-T1934
2mg35.00€5mg50.00€10mg66.00€25mg85.00€50mg124.00€100mg197.00€200mg255.00€1mL*10mM (DMSO)62.00€Piperlongumine
CAS:Piperlongumine (Piplartine) is a natural alkaloid from Piper longum L.Formula:C17H19NO5Purity:97.03% - 99.89%Color and Shape:SolidMolecular weight:317.34Vamifeport
CAS:Vamifeport (VIT-2763), an inhibitor targeting iron transport proteins, improves anemia and erythropoiesis and can be studied β-thalassemiaFormula:C21H21FN6O2Purity:99.26%Color and Shape:SolidMolecular weight:408.43Ref: TM-T39520
1mg115.00€5mg274.00€10mg432.00€25mg730.00€50mg1,026.00€100mg1,378.00€1mL*10mM (DMSO)303.00€(-)-Epigallocatechin Gallate
CAS:(-)-Epigallocatechin Gallate (EGCG) is an antioxidant polyphenol flavonoid that inhibits telomerase and DNA methyltransferase.Formula:C22H18O11Purity:98.08% - 99.43%Color and Shape:Yellow PowderMolecular weight:458.37NADPH tetrasodium salt
CAS:NADPH tetrasodium salt is the reduced form of the electron acceptor nicotinamide adenine dinucleotide phosphate, which acts as an electron donor in a variety ofFormula:C21H26N7Na4O17P3Purity:100% - 99.65%Color and Shape:SolidMolecular weight:833.35CP-24879 hydrochloride
CAS:CP-24879 HCl, a Δ5D/Δ6D dual-inhibitor, reduces liver lipid buildup and inflammation.Formula:C11H18ClNOPurity:98.78%Color and Shape:SolidMolecular weight:215.72Ref: TM-T27061
1mg49.00€5mg92.00€10mg145.00€25mg274.00€50mg472.00€100mg687.00€500mg1,444.00€1mL*10mM (DMSO)96.00€GPX4-IN-7
GPX4-IN-7 (Compound 31), an indirubin derivative, serves as a ferroptosis inducer in colon cancer treatment.Formula:C25H23ClN4O4Purity:98%Color and Shape:SolidMolecular weight:478.93
