Chromatin/Epigenetics
Chromatin/epigenetics inhibitors are compounds that modulate the structure and function of chromatin or interfere with epigenetic modifications, such as DNA methylation and histone modification. These inhibitors are essential tools for studying gene expression regulation and the role of epigenetics in diseases like cancer, neurological disorders, and developmental abnormalities. By targeting epigenetic processes, these inhibitors can alter gene expression patterns and offer new therapeutic avenues. At CymitQuimica, we provide a wide selection of high-quality chromatin/epigenetics inhibitors to support your research in molecular biology, genetics, and epigenetics.
Subcategories of "Chromatin/Epigenetics"
Products of "Chromatin/Epigenetics"
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3-methyl-1,2-dihydroquinolin-2-one
CAS:3-methyl-1,2-dihydroquinolin-2-one is the first known micromolar inhibitors of the ATAD2 bromodomain.Formula:C10H9NOPurity:99.62%Color and Shape:SolidMolecular weight:159.18Ref: TM-T50035
1mg50.00€5mg103.00€10mg155.00€25mg255.00€50mg375.00€100mg535.00€200mg725.00€1mL*10mM (DMSO)93.00€Molibresib
CAS:Molibresib (GSK525762) is an inhibitor of BET proteins (IC50: about 35 nM).Formula:C22H22ClN5O2Purity:97.70% - 99.08%Color and Shape:SolidMolecular weight:423.9Ref: TM-T1906
1mg43.00€2mg57.00€5mg93.00€10mg125.00€25mg216.00€50mg359.00€100mg535.00€200mg752.00€500mg1,169.00€1mL*10mM (DMSO)93.00€RG108
CAS:RG108 (N-Phthalyl-L-tryptophan) is an DNA methyltransferase inhibitor(IC50=115 nM).Formula:C19H14N2O4Purity:98% - 99.78%Color and Shape:SolidMolecular weight:334.33Ref: TM-T2038
5mg47.00€10mg69.00€25mg117.00€50mg205.00€100mg286.00€200mg401.00€500mg652.00€1mL*10mM (DMSO)56.00€KDM2B-IN-2
CAS:KDM2B-IN-2 is a potent histone demethylase (kdm2b) inhibitor.Formula:C21H26N4O2S2Purity:97.57%Color and Shape:SolidMolecular weight:430.59Ref: TM-T39389
1mg66.00€5mg144.00€10mg216.00€25mg406.00€50mg607.00€100mg845.00€500mg1,738.00€1mL*10mM (DMSO)159.00€PARP1-IN-5 dihydrochloride
CAS:PARP1-IN-5 dihydrochloride: oral, potent PARP-1 inhibitor (IC50=14.7 nM), for cancer research.Formula:C25H26Cl2N2O5SPurity:96.03%Color and Shape:SolidMolecular weight:537.46AMG 900
CAS:AMG 900 is a potent and highly selective pan-Aurora kinases inhibitor for Aurora A/B/C with IC50 of 5 nM/4 nM /1 nM.Formula:C28H21N7OSPurity:98.35% - 98.9%Color and Shape:SolidMolecular weight:503.58Ref: TM-T6380
1mg52.00€5mg97.00€10mg166.00€25mg303.00€50mg467.00€100mg682.00€500mg1,415.00€1mL*10mM (DMSO)105.00€TNG-462
CAS:TNG-462 is a oral, potent and selective PRMT5 inhibitor for the treatment of MTAP-deficient and/or MTA-accumulating cancers (e.g., pancreatic & bladder).Formula:C28H36N6O2SPurity:98.7%Color and Shape:SolidMolecular weight:520.69WDR5-0103 hydrochloride[890190-22-4(free base)]
WDR5-0103 hydrochloride[890190-22-4(free base)] (WD-Repeat Protein 5-0103) is an effective and specific WD repeat-containing protein 5 (WDR5) antagonist (Kd:Formula:C21H26ClN3O4Purity:99.66%Color and Shape:SolidMolecular weight:419.9BET BD2-IN-1
BET BD2-IN-1 (compound 45) is a potent, selective inhibitor of BET BD2, exhibiting an IC50 value of 1.6 nM.Purity:98%Color and Shape:Odour SolidC646
CAS:C646, a histone acetyltransferase inhibitor, inhibits p300 (Ki: 400 nM, in a cell-free assay).Formula:C24H19N3O6Purity:98% - 99.21%Color and Shape:SolidMolecular weight:445.42JNJ-42041935
CAS:JNJ-42041935 (HIF-PHD Inhibitor II) is a potent (pKi = 7.3-7.9), 2-oxoglutarate competitive, reversible, and selective inhibitor of PHD enzymes.Formula:C12H6ClF3N4O3Purity:99.58% - ≥95%Color and Shape:SolidMolecular weight:346.65Ref: TM-T3180
1mg40.00€2mg52.00€5mg88.00€10mg119.00€25mg210.00€50mg354.00€100mg567.00€500mg1,198.00€1mL*10mM (DMSO)87.00€Zebularine
CAS:Zebularine (4-Deoxyuridine) is a DNA methylation inhibitor.Formula:C9H12N2O5Purity:100% - 99.84%Color and Shape:SolidMolecular weight:228.2PROTAC SMARCA2 degrader-20
CAS:PROTAC SMARCA2 degrader-20 (Compound I-40) is a potent degrader of PROTAC SMARCA2, showing potential for cancer research applications.Formula:C55H65N11O5SColor and Shape:SolidMolecular weight:992.24CPI-1205
CAS:CPI-1205 是一种高效的选择性 EZH2 抑制剂(IC50:0.002 μM,EC50:0.032 μM)。Formula:C27H33F3N4O3Purity:98.71% - 99.7%Color and Shape:SolidMolecular weight:518.57Effusanin E
CAS:Effusanin E inhibits bacterial growth, counters cancer by blocking p50/p65 and reducing COX-2, halting NPC cell proliferation and triggering cell death.Formula:C20H28O6Purity:98%Color and Shape:SolidMolecular weight:364.438UNC7096
UNC7096 is a potent, selective degrader of NSD2-PWWP1, exhibiting a dissociation constant (Kd) of 46 nM, and shows promise for treating NSD2-related diseases [1Formula:C61H87N7O18SPurity:98%Color and Shape:SolidMolecular weight:1238.44PROTAC BRD4 Degrader-29
PROTAC BRD4 Degrader-29 (compound 7a) is a potent BRD4 PROTAC degrader with a DC50 of 89.4 nM, playing a significant role in cancer research.Formula:C58H61ClN10O9S2Molecular weight:1141.75PARP-1-IN-13
PARP-1-IN-13 (Compound 19c) is a potent PARP-1 inhibitor with an IC50 of 26 nM, hindering DNA single-strand break repair and exacerbating DNA double-strandFormula:C20H17N5O2SPurity:98%Color and Shape:SolidMolecular weight:391.45J-147
CAS:J-147, a curcumin derivative, is an experimental drug with reported effects against both Alzheimer's disease and ageing in mouse models of accelerated aging.Formula:C18H17F3N2O2Purity:100% - 99.61%Color and Shape:SolidMolecular weight:350.33BRD4 Inhibitor-27
CAS:BRD4 Inhibitor-27 is a potent BRD4 inhibitor that inhibits BRD4 BD1 and BRD4 BD2 with IC50s of 9.6 and 11.3 μM, respectively.BRD4 Inhibitor-27 has anticancerFormula:C16H13F3N6Purity:99.22%Color and Shape:SolidMolecular weight:346.31
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